Literature DB >> 25623135

Dynamic locking screw improves fixation strength in osteoporotic bone: an in vitro study on an artificial bone model.

Tim Pohlemann1, Boyko Gueorguiev, Yash Agarwal, Dieter Wahl, Christoph Sprecher, Karsten Schwieger, Mark Lenz.   

Abstract

PURPOSE: The novel dynamic locking screw (DLS) was developed to improve bone healing with locked-plate osteosynthesis by equalising construct stiffness at both cortices. Due to a theoretical damping effect, this modulated stiffness could be beneficial for fracture fixation in osteoporotic bone. Therefore, the mechanical behaviour of the DLS at the screw-bone interface was investigated in an artificial osteoporotic bone model and compared with conventional locking screws (LHS).
METHODS: Osteoporotic surrogate bones were plated with either a DLS or a LHS construct consisting of two screws and cyclically axially loaded (8,500 cycles, amplitude 420 N, increase 2 mN/cycle). Construct stiffness, relative movement, axial screw migration, proximal (P) and distal (D) screw pullout force and loosening at the bone interface were determined and statistically evaluated.
RESULTS: DLS constructs exhibited a higher screw pullout force of P 85 N [standard deviation (SD) 21] and D 93 N (SD 12) compared with LHS (P 62 N, SD 28, p = 0.1; D 57 N, SD 25, p < 0.01) and a significantly lower axial migration over cycles compared with LHS (p = 0.01). DLS constructs showed significantly lower axial construct stiffness (403 N/mm, SD 21, p < 0.01) and a significantly higher relative movement (1.1 mm, SD 0.05, p < 0.01) compared with LHS (529 N/mm, SD 27; 0.8 mm, SD 0.04).
CONCLUSION: Based on the model data, the DLS principle might also improve in vivo plate fixation in osteoporotic bone, providing enhanced residual holding strength and reducing screw cutout. The influence of pin-sleeve abutment still needs to be investigated.

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Year:  2015        PMID: 25623135     DOI: 10.1007/s00264-014-2658-6

Source DB:  PubMed          Journal:  Int Orthop        ISSN: 0341-2695            Impact factor:   3.075


  31 in total

Review 1.  Evolution of the internal fixation of long bone fractures. The scientific basis of biological internal fixation: choosing a new balance between stability and biology.

Authors:  Stephan M Perren
Journal:  J Bone Joint Surg Br       Date:  2002-11

2.  Effect of cortical thickness and cancellous bone density on the holding strength of internal fixator screws.

Authors:  J Seebeck; J Goldhahn; H Städele; P Messmer; M M Morlock; E Schneider
Journal:  J Orthop Res       Date:  2004-11       Impact factor: 3.494

3.  2010 mid-America Orthopaedic Association Physician in Training Award: healing complications are common after locked plating for distal femur fractures.

Authors:  Christopher E Henderson; Trevor J Lujan; Lori L Kuhl; Michael Bottlang; Daniel C Fitzpatrick; John L Marsh
Journal:  Clin Orthop Relat Res       Date:  2011-03-22       Impact factor: 4.176

4.  Stiffness modulation of locking plate constructs using near cortical slotted holes: a preliminary study.

Authors:  Michael J Gardner; Sean E Nork; Phillipe Huber; James C Krieg
Journal:  J Orthop Trauma       Date:  2009-04       Impact factor: 2.512

5.  Biomechanics of far cortical locking.

Authors:  Michael Bottlang
Journal:  J Orthop Trauma       Date:  2011-06       Impact factor: 2.512

6.  Delayed bone healing following high tibial osteotomy related to increased implant stiffness in locked plating.

Authors:  Götz Röderer; Florian Gebhard; Lutz Duerselen; Anita Ignatius; Lutz Claes
Journal:  Injury       Date:  2014-04-16       Impact factor: 2.586

7.  Less rigid stable fracture fixation in osteoporotic bone using locked plates with near cortical slots.

Authors:  Michael J Gardner; Sean E Nork; Phillipe Huber; James C Krieg
Journal:  Injury       Date:  2010-03-16       Impact factor: 2.586

8.  A new method of fixation in osteoporotic bone. A preliminary report.

Authors:  Tim Drew; Paul Allcock
Journal:  Injury       Date:  2002-10       Impact factor: 2.586

9.  Biomechanical testing of the LCP--how can stability in locked internal fixators be controlled?

Authors:  Karl Stoffel; Ulrich Dieter; Gwidon Stachowiak; André Gächter; Markus S Kuster
Journal:  Injury       Date:  2003-11       Impact factor: 2.586

10.  Controlled dynamic stability as the next step in "biologic plate osteosynthesis" - a pilot prospective observational cohort study in 34 patients with distal tibia fractures.

Authors:  Thomas Freude; Steffen Schröter; Christoph Emanuel Gonser; Ulrich Stöckle; Yves P Acklin; Dankwart Höntzsch; Stefan Döbele
Journal:  Patient Saf Surg       Date:  2014-01-21
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  2 in total

1.  Dynamic locked plating for fixation of distal femur fractures using near- cortical over-drilling: Preliminary results of a prospective observational study.

Authors:  Sherif Galal
Journal:  J Clin Orthop Trauma       Date:  2017-07-15

2.  History of internal fixation with plates (part 2): new developments after World War II; compressing plates and locked plates.

Authors:  Philippe Hernigou; Jacques Pariat
Journal:  Int Orthop       Date:  2016-12-30       Impact factor: 3.075

  2 in total

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