Less rigid stable fracture fixation in osteoporotic bone using locked plates with near cortical slots.

INTRODUCTION: Locked plating leads to improved fixation in osteoporotic bone. In addition, experimental data suggest that overall construct stiffness is increased. Ideal stiffness may be significantly less than that achieved with these locked constructs, and overly stiff constructs may lead to impaired fracture healing and stress concentration at the ends of the plate. In osteoporotic bone, this stiffness mismatch can be even more pronounced. We hypothesized that substituting slots for holes in the near cortex under a locked plate would lead to predictably lower stiffness without diminishing implant stability.
METHODS: Osteoporotic bone substitute segments were used. Locking screws and plates were applied to each specimen using either standard holes or near cortical slots. The slots were designed to allow axial displacement of the screw in the near cortex only, while continuing to provide some torsional stability. Mechanical testing was performed using a progressive dynamic displacement load protocol to determine failure and stiffness. Next, cyclic axial loading was performed with a physiologic load for 10,000 cycles to determine change in stiffness with cycling. Outcomes were compared between groups using Mann-Whitney U tests.
RESULTS: In the dynamic displacement tests, the slotted specimens reached both maximum load and failure load at a significantly greater displacement than the non-slot group (p=0.008), indicating later failure. The magnitude of the maximum load achieved was no different between groups. In the cyclic loading tests, the axial stiffness in the slotted group was significantly lower (1199 N/mm) than the non-slotted group (3538 N/mm; p<0.05 at all cycles). Stiffness did not change significantly in either group over the course of cycling. DISCUSSION: The ability to predictably adjust the axial stiffness of locked plating constructs is critical, particularly in osteoporotic bone. The use of near cortical slots decreases axial stiffness of locking plates, while maintaining fixation stability. This may allow the surgeon to more closely tailor the construct stiffness to the clinical situation to minimize stiffness mismatches and complications. Copyright 2010 Elsevier Ltd. All rights reserved.