Literature DB >> 2559420

The antiviral action of lignans.

W D MacRae, J B Hudson, G H Towers.   

Abstract

A total of 18 purified lignans was evaluated for antiviral activity against murine cytomegalovirus (CMV) and Sindbis virus, by means of different treatment regimens. Podophyllotoxin and alpha-peltatin were the most potent compounds, and they apparently inhibited murine CMV at an essential early step in the replication cycle after the adsorption of virus to the cells. On the other hand, justicidin B and the diphyllin derivatives were much more effective against Sindbis virus, and 12 of the lignans had no demonstrable effect at all, despite their known activities in other bioassays.

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Year:  1989        PMID： 2559420     DOI： 10.1055/s-2006-962087

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  11 in total

1.  Design, synthesis, and cytotoxicity of perbutyrylated glycosides of 4β-triazolopodophyllotoxin derivatives.

Authors:  Cheng-Ting Zi; Zhen-Hua Liu; Gen-Tao Li; Yan Li; Jun Zhou; Zhong-Tao Ding; Jiang-Miao Hu; Zi-Hua Jiang
Journal:  Molecules       Date:  2015-02-16       Impact factor: 4.411

2.  The western red cedar (Thuja plicata) 8-8' DIRIGENT family displays diverse expression patterns and conserved monolignol coupling specificity.

Authors:  Myoung K Kim; Jae-Heung Jeon; Masayuki Fujita; Laurence B Davin; Norman G Lewis
Journal:  Plant Mol Biol       Date:  2002-05       Impact factor: 4.076

3.  Elenoside increases intestinal motility.

Authors:  E Navarro; S-J Alonso; R Navarro; J Trujillo; E Jorge
Journal:  World J Gastroenterol       Date:  2006-11-28       Impact factor: 5.742

4.  Synthesis and evaluation of ether-linked demethylepipodophyllotoxin dimers.

Authors:  Norma Dunlap; Tracy L J Salyard; Anuradha Liyana Pathiranage; Jeannie Stubblefield; Steven L Pitts; Rachel E Ashley; Neil Osheroff
Journal:  Bioorg Med Chem Lett       Date:  2014-11-01       Impact factor: 2.823

5.  Anti-infective and cytotoxic properties of Bupleurum marginatum.

Authors:  Mohamed L Ashour; Mahmoud Z El-Readi; Razan Hamoud; Safaa Y Eid; Sherweit H El Ahmady; Endalkachew Nibret; Florian Herrmann; Mahmoud Youns; Ahmed Tahrani; Dorothea Kaufmann; Michael Wink
Journal:  Chin Med       Date:  2014-01-17       Impact factor: 5.455

6.  Anti-human immunodeficiency virus (HIV) activities of halogenated gomisin J derivatives, new nonnucleoside inhibitors of HIV type 1 reverse transcriptase.

Authors:  T Fujihashi; H Hara; T Sakata; K Mori; H Higuchi; A Tanaka; H Kaji; A Kaji
Journal:  Antimicrob Agents Chemother       Date:  1995-09       Impact factor: 5.191

Review 7.  Podophyllotoxin: History, Recent Advances and Future Prospects.

Authors:  Zinnia Shah; Umar Farooq Gohar; Iffat Jamshed; Aamir Mushtaq; Hamid Mukhtar; Muhammad Zia-Ui-Haq; Sebastian Ionut Toma; Rosana Manea; Marius Moga; Bianca Popovici
Journal:  Biomolecules       Date:  2021-04-19

8.  Glucoside Derivatives Of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity.

Authors:  Cheng-Ting Zi; Liu Yang; Qing-Hua Kong; Hong-Mei Li; Xing-Zhi Yang; Zhong-Tao Ding; Zi-Hua Jiang; Jiang-Miao Hu; Jun Zhou
Journal:  Drug Des Devel Ther       Date:  2019-10-23       Impact factor: 4.162

9.  Linum narbonense: A new valuable tool for biotechnological production of a potent anticancer lignan Justicidine B.

Authors:  Iliana Ionkova; Pavlina Sasheva; Todor Ionkov; Georgi Momekov
Journal:  Pharmacogn Mag       Date:  2013-01       Impact factor: 1.085

10.  On the Physicochemical Characteristics and Applications of an "Undesirable" Pyrenean Thorny Cushion Dwarf: Echinospartum horridum (Vahl) Roth.

Authors:  Pablo Martín-Ramos; Jesús Martín-Gil; Daniel Gómez-García; José Antonio Cuchí-Oterino
Journal:  Plants (Basel)       Date:  2020-09-11
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