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Literature DB >> 2552293

A 125-base-pair CEN6 DNA fragment is sufficient for complete meiotic and mitotic centromere functions in Saccharomyces cerevisiae.

G Cottarel¹, J H Shero, P Hieter, J H Hegemann.

Abstract

Saccharomyces cerevisiae centromeres contain a conserved region ranging from 111 to 119 base pairs (bp) in length, which is characterized by the three conserved DNA elements CDEI, CDEII, and CDEIII. We isolated a 125-bp CEN6 DNA fragment (named ML CEN6) containing only these conserved elements and assayed it completely separated from its chromosomal context on circular minichromosomes and on a large linear chromosome fragment. The results show that this 125-bp CEN6 DNA fragment is by itself sufficient for complete mitotic and meiotic centromere functions.

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Year: 1989 PMID： 2552293 PMCID： PMC362379 DOI： 10.1128/mcb.9.8.3342-3349.1989

Source DB: PubMed Journal: Mol Cell Biol ISSN： 0270-7306 Impact factor: 4.272

24 in total

1. Functional selection and analysis of yeast centromeric DNA.

Authors: P Hieter; D Pridmore; J H Hegemann; M Thomas; R W Davis; P Philippsen
Journal: Cell Date: 1985-10 Impact factor: 41.582

Review 2. The structure and function of yeast centromeres.

Authors: L Clarke; J Carbon
Journal: Annu Rev Genet Date: 1985 Impact factor: 16.830

3. Meiotic Diploid Progeny and Meiotic Nondisjunction in SACCHAROMYCES CEREVISIAE.

Authors: S Sora; G Lucchini; G E Magni
Journal: Genetics Date: 1982-05 Impact factor: 4.562

4. Genomic substitutions of centromeres in Saccharomyces cerevisiae.

Authors: L Clarke; J Carbon
Journal: Nature Date: 1983 Sep 1-7 Impact factor: 49.962

5. Mutational analysis of centromere DNA from chromosome VI of Saccharomyces cerevisiae.

Authors: J H Hegemann; J H Shero; G Cottarel; P Philippsen; P Hieter
Journal: Mol Cell Biol Date: 1988-06 Impact factor: 4.272

6. Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis.

Authors: D C Schwartz; C R Cantor
Journal: Cell Date: 1984-05 Impact factor: 41.582

7. Structure and sequence of the centromeric DNA of chromosome 4 in Saccharomyces cerevisiae.

Authors: C Mann; R W Davis
Journal: Mol Cell Biol Date: 1986-01 Impact factor: 4.272

8. Genetic manipulation of centromere function.

Authors: A Hill; K Bloom
Journal: Mol Cell Biol Date: 1987-07 Impact factor: 4.272

9. Mutational and in vitro protein-binding studies on centromere DNA from Saccharomyces cerevisiae.

Authors: R Ng; J Carbon
Journal: Mol Cell Biol Date: 1987-12 Impact factor: 4.272

10. Isolation of a yeast centromere and construction of functional small circular chromosomes.

Authors: L Clarke; J Carbon
Journal: Nature Date: 1980-10-09 Impact factor: 49.962

70 in total

Review 1. Complex regulation of sister kinetochore orientation in meiosis-I.

Authors: Amit Bardhan
Journal: J Biosci Date: 2010-09 Impact factor: 1.826

2. In vivo characterization of the Saccharomyces cerevisiae centromere DNA element I, a binding site for the helix-loop-helix protein CPF1.

Authors: R Niedenthal; R Stoll; J H Hegemann
Journal: Mol Cell Biol Date: 1991-07 Impact factor: 4.272

Review 3. Putting CENP-A in its place.

Authors: Madison E Stellfox; Aaron O Bailey; Daniel R Foltz
Journal: Cell Mol Life Sci Date: 2012-06-23 Impact factor: 9.261

10. Mutational analysis of centromeric DNA elements of Kluyveromyces lactis and their role in determining the species specificity of the highly homologous centromeres from K. lactis and Saccharomyces cerevisiae.

Authors: J J Heus; B J Zonneveld; H Y Steensma; J A Van den Berg
Journal: Mol Gen Genet Date: 1994-05-10