Literature DB >> 2076551

Centromeric DNA of Kluyveromyces lactis.

J J Heus1, B J Zonneveld, H Y Steensma, J A Van den Berg.   

Abstract

A direct selection method was used to isolate centromeres from a genomic library of the yeast Kluyveromyces lactis. The method is based on the lethality at high copy number of the ochre-suppressing tRNA gene SUP11. Five different chromosomal fragments were found that confer mitotic stability to plasmids containing a replication origin of K. lactis (KARS). In addition, KARS plasmids containing these fragments have a copy number of approximately one, and each of the five fragments hybridizes to a different chromosome of K. lactis. From these results we conclude that five of the six centromeres of K. lactis have been isolated. These centromeres do not function in S. cerevisiae.

Entities:  

Mesh:

Substances:

Year:  1990        PMID: 2076551     DOI: 10.1007/BF00327022

Source DB:  PubMed          Journal:  Curr Genet        ISSN: 0172-8083            Impact factor:   3.886


  33 in total

1.  Composite motifs and repeat symmetry in S. pombe centromeres: direct analysis by integration of NotI restriction sites.

Authors:  Y Chikashige; N Kinoshita; Y Nakaseko; T Matsumoto; S Murakami; O Niwa; M Yanagida
Journal:  Cell       Date:  1989-06-02       Impact factor: 41.582

2.  Long-range organization of tandem arrays of alpha satellite DNA at the centromeres of human chromosomes: high-frequency array-length polymorphism and meiotic stability.

Authors:  R Wevrick; H F Willard
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

3.  Yeast centromeres: structure and function.

Authors:  J Carbon
Journal:  Cell       Date:  1984-06       Impact factor: 41.582

4.  Analysis of gene control signals by DNA fusion and cloning in Escherichia coli.

Authors:  M J Casadaban; S N Cohen
Journal:  J Mol Biol       Date:  1980-04       Impact factor: 5.469

5.  A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli.

Authors:  C S Hoffman; F Winston
Journal:  Gene       Date:  1987       Impact factor: 3.688

6.  Characterization of 2-mum DNA of Saccharomyces cerevisiae by restriction fragment analysis and integration in an Escherichia coli plasmid.

Authors:  C P Hollenberg; A Degelmann; B Kustermann-Kuhn; H D Royer
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205

7.  Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

Authors:  M Johnston; R W Davis
Journal:  Mol Cell Biol       Date:  1984-08       Impact factor: 4.272

8.  Analysis of centromeric DNA in the fission yeast Schizosaccharomyces pombe.

Authors:  L Clarke; H Amstutz; B Fishel; J Carbon
Journal:  Proc Natl Acad Sci U S A       Date:  1986-11       Impact factor: 11.205

9.  Isolation of a yeast centromere and construction of functional small circular chromosomes.

Authors:  L Clarke; J Carbon
Journal:  Nature       Date:  1980-10-09       Impact factor: 49.962

10.  Stabilization of dicentric chromosomes in Saccharomyces cerevisiae by telomere addition to broken ends or by centromere deletion.

Authors:  D Jäger; P Philippsen
Journal:  EMBO J       Date:  1989-01       Impact factor: 11.598

View more
  23 in total

1.  Multifunctional centromere binding factor 1 is essential for chromosome segregation in the human pathogenic yeast Candida glabrata.

Authors:  T Stoyan; G Gloeckner; S Diekmann; J Carbon
Journal:  Mol Cell Biol       Date:  2001-08       Impact factor: 4.272

2.  Structure of the Centromere Binding Factor 3 Complex from Kluyveromyces lactis.

Authors:  Phong D Lee; Hui Wei; Dongyan Tan; Stephen C Harrison
Journal:  J Mol Biol       Date:  2019-08-17       Impact factor: 5.469

3.  A mutation in the STN1 gene triggers an alternative lengthening of telomere-like runaway recombinational telomere elongation and rapid deletion in yeast.

Authors:  Shilpa Iyer; Ashley D Chadha; Michael J McEachern
Journal:  Mol Cell Biol       Date:  2005-09       Impact factor: 4.272

4.  The nucleosome repeat length of Kluyveromyces lactis is 16 bp longer than that of Saccharomyces cerevisiae.

Authors:  J J Heus; B J Zonneveld; K S Bloom; H Y de Steensma; J A van den Berg
Journal:  Nucleic Acids Res       Date:  1993-05-11       Impact factor: 16.971

5.  KNQ1, a Kluyveromyces lactis gene encoding a drug efflux permease.

Authors:  Maria Takacova; Denisa Imrichova; Jana Cernicka; Yvetta Gbelska; Julius Subik
Journal:  Curr Genet       Date:  2003-11-01       Impact factor: 3.886

6.  Chromatin structures of Kluyveromyces lactis centromeres in K. lactis and Saccharomyces cerevisiae.

Authors:  J J Heus; K S Bloom; B J Zonneveld; H Y Steensma; J A Van den Berg
Journal:  Chromosoma       Date:  1993-11       Impact factor: 4.316

7.  Mutational analysis of centromeric DNA elements of Kluyveromyces lactis and their role in determining the species specificity of the highly homologous centromeres from K. lactis and Saccharomyces cerevisiae.

Authors:  J J Heus; B J Zonneveld; H Y Steensma; J A Van den Berg
Journal:  Mol Gen Genet       Date:  1994-05-10

8.  The hexokinase gene is required for transcriptional regulation of the glucose transporter gene RAG1 in Kluyveromyces lactis.

Authors:  C Prior; P Mamessier; H Fukuhara; X J Chen; M Wesolowski-Louvel
Journal:  Mol Cell Biol       Date:  1993-07       Impact factor: 4.272

9.  Coregulation of the Kluyveromyces lactis lactose permease and beta-galactosidase genes is achieved by interaction of multiple LAC9 binding sites in a 2.6 kbp divergent promoter.

Authors:  A Gödecke; W Zachariae; A Arvanitidis; K D Breunig
Journal:  Nucleic Acids Res       Date:  1991-10-11       Impact factor: 16.971

10.  The consensus sequence of Kluyveromyces lactis centromeres shows homology to functional centromeric DNA from Saccharomyces cerevisiae.

Authors:  J J Heus; B J Zonneveld; H Y de Steensma; J A van den Berg
Journal:  Mol Gen Genet       Date:  1993-01
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.