| Literature DB >> 25498478 |
Jing Pan1, Feiran Li1, Tae-Gon Cha1, Haorong Chen1, Jong Hyun Choi2.
Abstract
DNA based synthetic molecular walkers are reminiscent of biological protein motors. They are powered by hybridization with fuel strands, environment induced conformational transitions, and covalent chemistry of oligonucleotides. Recent developments in experimental techniques enable direct observation of individual walkers with high temporal and spatial resolution. The functionalities of state-of-the-art DNA walker systems can thus be analyzed for various applications. Herein we review recent progress on DNA walker principles and characterization methods, and evaluate various aspects of their functions for future applications.Entities:
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Year: 2014 PMID: 25498478 DOI: 10.1016/j.copbio.2014.11.017
Source DB: PubMed Journal: Curr Opin Biotechnol ISSN: 0958-1669 Impact factor: 9.740