Literature DB >> 25470566

NMR hyperpolarization techniques for biomedicine.

Panayiotis Nikolaou1, Boyd M Goodson, Eduard Y Chekmenev.   

Abstract

Recent developments in NMR hyperpolarization have enabled a wide array of new in vivo molecular imaging modalities, ranging from functional imaging of the lungs to metabolic imaging of cancer. This Concept article explores selected advances in methods for the preparation and use of hyperpolarized contrast agents, many of which are already at or near the phase of their clinical validation in patients.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  dynamic nuclear polarization; hyperpolarization; medicinal chemistry; molecular imaging; spin exchange optical pumping

Mesh：

Substances：

Year:  2014        PMID： 25470566      PMCID： PMC4418426          DOI： 10.1002/chem.201405253

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  102 in total

1.  Functionalized xenon as a biosensor.

Authors:  M M Spence; S M Rubin; I E Dimitrov; E J Ruiz; D E Wemmer; A Pines; S Q Yao; F Tian; P G Schultz
Journal:  Proc Natl Acad Sci U S A       Date:  2001-09-04       Impact factor: 11.205

Review 2.  Nuclear magnetic resonance of laser-polarized noble gases in molecules, materials, and organisms.

Authors:  Boyd M Goodson
Journal:  J Magn Reson       Date:  2002-04       Impact factor: 2.229

3.  A 3D-printed high power nuclear spin polarizer.

Authors:  Panayiotis Nikolaou; Aaron M Coffey; Laura L Walkup; Brogan M Gust; Cristen D LaPierre; Edward Koehnemann; Michael J Barlow; Matthew S Rosen; Boyd M Goodson; Eduard Y Chekmenev
Journal:  J Am Chem Soc       Date:  2014-01-21       Impact factor: 15.419

Review 4.  The theory and practice of hyperpolarization in magnetic resonance using parahydrogen.

Authors:  Richard A Green; Ralph W Adams; Simon B Duckett; Ryan E Mewis; David C Williamson; Gary G R Green
Journal:  Prog Nucl Magn Reson Spectrosc       Date:  2012-03-15       Impact factor: 9.795

5.  Para-hydrogenated glucose derivatives as potential 13C-hyperpolarized probes for magnetic resonance imaging.

Authors:  Francesca Reineri; Daniela Santelia; Alessandra Viale; Erika Cerutti; Luisa Poggi; Tomas Tichy; Samuel S D Premkumar; Roberto Gobetto; Silvio Aime
Journal:  J Am Chem Soc       Date:  2010-05-26       Impact factor: 15.419

6.  XeNA: an automated 'open-source' (129)Xe hyperpolarizer for clinical use.

Authors:  Panayiotis Nikolaou; Aaron M Coffey; Laura L Walkup; Brogan M Gust; Nicholas Whiting; Hayley Newton; Iga Muradyan; Mikayel Dabaghyan; Kaili Ranta; Gregory D Moroz; Matthew S Rosen; Samuel Patz; Michael J Barlow; Eduard Y Chekmenev; Boyd M Goodson
Journal:  Magn Reson Imaging       Date:  2014-02-10       Impact factor: 2.546

7.  Development of an antibody-based, modular biosensor for 129Xe NMR molecular imaging of cells at nanomolar concentrations.

Authors:  Honor M Rose; Christopher Witte; Federica Rossella; Stefan Klippel; Christian Freund; Leif Schröder
Journal:  Proc Natl Acad Sci U S A       Date:  2014-07-28       Impact factor: 11.205

8.  Hyperpolarized choline as an MR imaging molecular probe: feasibility of in vivo imaging in a rat model.

Authors:  Lanette J Friesen-Waldner; Trevor P Wade; Kundan Thind; Albert P Chen; J Moshe Gomori; Jacob Sosna; Charles A McKenzie; Rachel Katz-Brull
Journal:  J Magn Reson Imaging       Date:  2014-05-27       Impact factor: 4.813

Review 9.  Para-hydrogen perspectives in hyperpolarized NMR.

Authors:  Stefan Glöggler; Johannes Colell; Stephan Appelt
Journal:  J Magn Reson       Date:  2013-07-24       Impact factor: 2.229

10.  Distribution of hyperpolarized xenon in the brain following sensory stimulation: preliminary MRI findings.

Authors:  Mary L Mazzanti; Ronn P Walvick; Xin Zhou; Yanping Sun; Niral Shah; Joey Mansour; Jessica Gereige; Mitchell S Albert
Journal:  PLoS One       Date:  2011-07-15       Impact factor: 3.240
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  111 in total

1.  Hyperpolarizing Concentrated Metronidazole 15 NO2 Group over Six Chemical Bonds with More than 15 % Polarization and a 20 Minute Lifetime.

Authors:  Roman V Shchepin; Jonathan R Birchall; Nikita V Chukanov; Kirill V Kovtunov; Igor V Koptyug; Thomas Theis; Warren S Warren; Juri G Gelovani; Boyd M Goodson; Sepideh Shokouhi; Matthew S Rosen; Yi-Fen Yen; Wellington Pham; Eduard Y Chekmenev
Journal:  Chemistry       Date:  2019-05-30       Impact factor: 5.236

Review 2.  NMR-based Stable Isotope Resolved Metabolomics in systems biochemistry.

Authors:  Andrew N Lane; Teresa W-M Fan
Journal:  Arch Biochem Biophys       Date:  2017-03-02       Impact factor: 4.013

3.  Spin-Lattice Relaxation of Hyperpolarized Metronidazole in Signal Amplification by Reversible Exchange in Micro-Tesla Fields.

Authors:  Roman V Shchepin; Lamya Jaigirdar; Eduard Y Chekmenev
Journal:  J Phys Chem C Nanomater Interfaces       Date:  2018-02-27       Impact factor: 4.126

4.  Spin Relays Enable Efficient Long-Range Heteronuclear Signal Amplification By Reversible Exchange.

Authors:  Roman V Shchepin; Lamya Jaigirdar; Thomas Theis; Warren S Warren; Boyd M Goodson; Eduard Y Chekmenev
Journal:  J Phys Chem C Nanomater Interfaces       Date:  2017-12-01       Impact factor: 4.126

5.  Toward Production of Pure 13C Hyperpolarized Metabolites Using Heterogeneous Parahydrogen-Induced Polarization of Ethyl[1-13C]acetate.

Authors:  K V Kovtunov; D A Barskiy; O G Salnikov; R V Shchepin; A M Coffey; L M Kovtunova; V I Bukhtiyarov; I V Koptyug; E Y Chekmenev
Journal:  RSC Adv       Date:  2016-07-15       Impact factor: 3.361

6.  Heterogeneous Parahydrogen Pairwise Addition to Cyclopropane.

Authors:  Oleg G Salnikov; Kirill V Kovtunov; Panayiotis Nikolaou; Larisa M Kovtunova; Valerii I Bukhtiyarov; Igor V Koptyug; Eduard Y Chekmenev
Journal:  Chemphyschem       Date:  2018-08-07       Impact factor: 3.102

7.  Imaging of Biomolecular NMR Signals Amplified by Reversible Exchange with Parahydrogen Inside an MRI Scanner.

Authors:  Kirill V Kovtunov; Bryce E Kidd; Oleg G Salnikov; Liana B Bales; Max E Gemeinhardt; Jonathan Gesiorski; Roman V Shchepin; Eduard Y Chekmenev; Boyd M Goodson; Igor V Koptyug
Journal:  J Phys Chem C Nanomater Interfaces       Date:  2017-11-01       Impact factor: 4.126

8.  Automated pneumatic shuttle for magnetic field cycling and parahydrogen hyperpolarized multidimensional NMR.

Authors:  Patrick TomHon; Evan Akeroyd; Sören Lehmkuhl; Eduard Y Chekmenev; Thomas Theis
Journal:  J Magn Reson       Date:  2020-02-04       Impact factor: 2.229

9.  Quasi-Resonance Signal Amplification by Reversible Exchange.

Authors:  Thomas Theis; Nuwandi M Ariyasingha; Roman V Shchepin; Jacob R Lindale; Warren S Warren; Eduard Y Chekmenev
Journal:  J Phys Chem Lett       Date:  2018-10-10       Impact factor: 6.475

Review 10.  MR Imaging Biomarkers in Oncology Clinical Trials.

Authors:  Richard G Abramson; Lori R Arlinghaus; Adrienne N Dula; C Chad Quarles; Ashley M Stokes; Jared A Weis; Jennifer G Whisenant; Eduard Y Chekmenev; Igor Zhukov; Jason M Williams; Thomas E Yankeelov
Journal:  Magn Reson Imaging Clin N Am       Date:  2016-02       Impact factor: 2.266
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