Literature DB >> 2540343

Superoxide dismutase and cytochrome oxidase activities in light and heavy synaptic mitochondria from rat cerebral cortex during aging.

A Vanella1, R F Villa, A Gorini, A Campisi, A M Giuffrida-Stella.   

Abstract

The specific activities of superoxide dismutase (SOD) and cytochrome oxidase (COX) in light and heavy synaptic mitochondria from rat cerebral cortex at different ages (4, 8, 12, 16, 20, and 24 months) have been measured. The specific activity of COX was significantly higher in light synaptic mitochondria than in heavy ones at all ages examined. However, no significant difference during aging was shown. A marked decrease of SOD in light and heavy synaptic mitochondria during aging was observed.

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Year:  1989        PMID： 2540343     DOI： 10.1002/jnr.490220316

Source DB:  PubMed          Journal:  J Neurosci Res        ISSN： 0360-4012            Impact factor:   4.164


  7 in total

1.  Structural and functional aspects of the respiratory chain of synaptic and nonsynaptic mitochondria derived from selected brain regions.

Authors:  M Battino; E Bertoli; G Formiggini; S Sassi; A Gorini; R F Villa; G Lenaz
Journal:  J Bioenerg Biomembr       Date:  1991-04       Impact factor: 2.945

2.  Anti-oxidant defences and peroxidation in liver and brain of aged rats.

Authors:  G Barja de Quiroga; R Pérez-Campo; M López Torres
Journal:  Biochem J       Date:  1990-11-15       Impact factor: 3.857

3.  Cerebral cortex synaptic heavy mitochondria may represent the oldest synaptic mitochondrial population: biochemical heterogeneity and effects of L-acetylcarnitine.

Authors:  M Battino; J L Quiles; J R Huertas; J F Mataix; R F Villa; A Gorini
Journal:  J Bioenerg Biomembr       Date:  2000-04       Impact factor: 2.945

4.  Lipid peroxidation and antioxidant enzymatic systems in rat retina as a function of age.

Authors:  C Castorina; A Campisi; C Di Giacomo; V Sorrenti; A Russo; A Vanella
Journal:  Neurochem Res       Date:  1992-06       Impact factor: 3.996

5.  Analyses of energy metabolism and mitochondrial genome in post-mortem brain from patients with Alzheimer's disease.

Authors:  H Reichmann; S Flörke; G Hebenstreit; H Schrubar; P Riederer
Journal:  J Neurol       Date:  1993-06       Impact factor: 4.849

6.  Age-related increases in superoxide dismutase activity and thiobarbituric acid-reactive substances: effect of bio-catalyzer in aged rat brain.

Authors:  L A Santiago; J A Osato; J Liu; A Mori
Journal:  Neurochem Res       Date:  1993-06       Impact factor: 3.996

7.  Concentrations of several proteins characteristic of nervous tissue in cerebral cortex of patients with Alzheimer's disease.

Authors:  K Kato; N Kurobe; F Suzuki; R Morishita; T Asano; T Sato; T Inagaki
Journal:  J Mol Neurosci       Date:  1991       Impact factor: 3.444
  7 in total

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