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Literature DB >> 1603266

Lipid peroxidation and antioxidant enzymatic systems in rat retina as a function of age.

C Castorina¹, A Campisi, C Di Giacomo, V Sorrenti, A Russo, A Vanella.

Abstract

In the present study, we have assayed the enzymatic activity of Cu,Zn-SOD, Mn-SOD, GSH-Px, GSH-Red, Cat, and G6PD in rat retina as a function of age. Conjugated diene levels and MDA formation were also determined. The conjugated diene levels in rat retina were found to increase significantly with age, accompanied by a marked decrease in GSH-Px and Cat activities. No age-related change in MDA levels and in GSH-Red and G6PD activity was found, whereas a significant increase in SOD activity was observed between 1 and 4 months. Decreased GSH-Px and Cat activity is related to increased lipid peroxidation with age.

Entities: Chemical Gene Species

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Year: 1992 PMID： 1603266 DOI： 10.1007/bf00968789

Source DB: PubMed Journal: Neurochem Res ISSN： 0364-3190 Impact factor: 3.996

39 in total

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11 in total

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Journal: Am J Clin Nutr Date: 2011-07-27 Impact factor: 7.045

Review 2. Consequences of oxidative stress in age-related macular degeneration.

Authors: Stuart G Jarrett; Michael E Boulton
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3. Microsomal glutathione S-transferase 1 in the retinal pigment epithelium: protection against oxidative stress and a potential role in aging.

Authors: Akiko Maeda; John W Crabb; Krzysztof Palczewski
Journal: Biochemistry Date: 2005-01-18 Impact factor: 3.162

Review 4. Age-related retinal degeneration in animal models of aging: possible involvement of taurine deficiency and oxidative stress.

Authors: Julius Militante; John B Lombardini
Journal: Neurochem Res Date: 2004-01 Impact factor: 3.996

5. Inflammatory priming predisposes mice to age-related retinal degeneration.

Authors: Debarshi Mustafi; Tadao Maeda; Hideo Kohno; Joseph H Nadeau; Krzysztof Palczewski
Journal: J Clin Invest Date: 2012-07-17 Impact factor: 14.808

Review 6. Taurine and oxidative stress in retinal health and disease.

Authors: Vanessa Castelli; Antonella Paladini; Michele d'Angelo; Marcello Allegretti; Flavio Mantelli; Laura Brandolini; Pasquale Cocchiaro; Annamaria Cimini; Giustino Varrassi
Journal: CNS Neurosci Ther Date: 2021-02-23 Impact factor: 5.243

7. Lipid peroxidation and total antioxidant capacity in vitreous, aqueous humor, and blood samples from patients with diabetic retinopathy.

Authors: Raffaele Mancino; Donato Di Pierro; Chiara Varesi; Angelica Cerulli; Alessandra Feraco; Claudio Cedrone; Maria Dolores Pinazo-Duran; Massimiliano Coletta; Carlo Nucci
Journal: Mol Vis Date: 2011-05-07 Impact factor: 2.367