Literature DB >> 25270264

Patient-specific ultrasound liver phantom: materials and fabrication method.

Alessia Pacioni1, Marina Carbone, Cinzia Freschi, Rosanna Viglialoro, Vincenzo Ferrari, Mauro Ferrari.   

Abstract

PURPOSE: An anatomically realistic ultrasound liver phantom with tissue-specific distinct signal properties is needed for training of novices in diagnostic and interventional procedures. The main objective of this work was development and testing of a new durable liver ultrasound training phantom for use with a hybrid simulator.
METHODS: A liver ultrasound phantom was fabricated in four main phases: materials selection, segmentation of CT images and realization of 3D models, vessel and lesion realization, and final assembly with silicone casting. Silicone was used as basic material due to its durability and stability over time. Several additives were analyzed and mixed with the polymer to reproduce the echogenicity of three simulated soft tissue types: parenchyma, lesions, and veins.
RESULTS: Cysts and vessel trees appear anechoic in the B mode ultrasound images when realized with pure silicone. The liver parenchyma, hypoechoic, and hyperechoic lesions were realized with different concentrations of graphite and Vaseline oil to increase their relative echogenicity. These materials were successful for creation of an ultrasound liver phantom containing simulated blood vessels and lesions.
CONCLUSION: The phantom reproduces the human liver morphology and provides vessels and lesions ultrasound images with recognizable differences in echogenicity. The speed of sound in the simulated materials is inaccurate, but the problem can be overcome via software adjustment in a hybrid simulator.

Entities:  

Mesh:

Year:  2014        PMID: 25270264     DOI: 10.1007/s11548-014-1120-y

Source DB:  PubMed          Journal:  Int J Comput Assist Radiol Surg        ISSN: 1861-6410            Impact factor:   2.924


  22 in total

Review 1.  A review of tissue substitutes for ultrasound imaging.

Authors:  Martin O Culjat; David Goldenberg; Priyamvada Tewari; Rahul S Singh
Journal:  Ultrasound Med Biol       Date:  2010-06       Impact factor: 2.998

Review 2.  The role of medical simulation: an overview.

Authors:  Kevin Kunkler
Journal:  Int J Med Robot       Date:  2006-09       Impact factor: 2.547

3.  In vivo mechanical characterization of human liver.

Authors:  A Nava; E Mazza; M Furrer; P Villiger; W H Reinhart
Journal:  Med Image Anal       Date:  2007-10-23       Impact factor: 8.545

4.  High frequency poroelastic waves in hydrogels.

Authors:  Piero Chiarelli; Antonio Lanatà; Marina Carbone; Claudio Domenici
Journal:  J Acoust Soc Am       Date:  2010-03       Impact factor: 1.840

5.  Evaluation of the particulate concentration in a gelatin-based phantom for sonographically guided lesion biopsy.

Authors:  Jan F Gerstenmaier; Colin J McCarthy; David P Brophy; Colin P Cantwell
Journal:  J Ultrasound Med       Date:  2013-08       Impact factor: 2.153

Review 6.  Simulators for training in ultrasound guided procedures.

Authors:  Syed Farjad Sultan; George Shorten; Gabrielle Iohom
Journal:  Med Ultrason       Date:  2013-06       Impact factor: 1.611

7.  Effect of graphite concentration on shear-wave speed in gelatin-based tissue-mimicking phantoms.

Authors:  Pamela G Anderson; Ned C Rouze; Mark L Palmeri
Journal:  Ultrason Imaging       Date:  2011-04       Impact factor: 1.578

8.  A realistic deformable prostate phantom for multimodal imaging and needle-insertion procedures.

Authors:  Nikolai Hungr; Jean-Alexandre Long; Vincent Beix; Jocelyne Troccaz
Journal:  Med Phys       Date:  2012-04       Impact factor: 4.071

9.  Hybrid simulation using mixed reality for interventional ultrasound imaging training.

Authors:  C Freschi; S Parrini; N Dinelli; M Ferrari; V Ferrari
Journal:  Int J Comput Assist Radiol Surg       Date:  2014-09-12       Impact factor: 2.924

10.  Value of multidetector computed tomography image segmentation for preoperative planning in general surgery.

Authors:  Vincenzo Ferrari; Marina Carbone; Carla Cappelli; Luigi Boni; Franca Melfi; Mauro Ferrari; Franco Mosca; Andrea Pietrabissa
Journal:  Surg Endosc       Date:  2011-09-23       Impact factor: 4.584

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  9 in total

1.  Image-guided minimally invasive endopancreatic surgery using a computer-assisted navigation system.

Authors:  Philip C Müller; Caroline Haslebacher; Daniel C Steinemann; Beat P Müller-Stich; Thilo Hackert; Matthias Peterhans; Benjamin Eigl
Journal:  Surg Endosc       Date:  2020-04-06       Impact factor: 4.584

2.  Patient-specific brain arteries molded as a flexible phantom model using 3D printed water-soluble resin.

Authors:  Daniel P G Nilsson; Madelene Holmgren; Petter Holmlund; Anders Wåhlin; Anders Eklund; Tobias Dahlberg; Krister Wiklund; Magnus Andersson
Journal:  Sci Rep       Date:  2022-06-17       Impact factor: 4.996

3.  Anthropomorphic liver phantom with flow for multimodal image-guided liver therapy research and training.

Authors:  Anna Rethy; Jørn Ove Sæternes; Jostein Halgunset; Ronald Mårvik; Erlend F Hofstad; Juan A Sánchez-Margallo; Thomas Langø
Journal:  Int J Comput Assist Radiol Surg       Date:  2017-09-19       Impact factor: 2.924

4.  Dynamic Hepatocellular Carcinoma Model Within a Liver Phantom for Multimodality Imaging.

Authors:  Muntaser S Ahmad; Nursakinah Suardi; Ahmad Shukri; Nik Noor Ashikin Nik Ab Razak; Ammar A Oglat; Osama Makhamrah; Hjouj Mohammad
Journal:  Eur J Radiol Open       Date:  2020-09-03

5.  A Multimodal Pancreas Phantom for Computer-Assisted Surgery Training.

Authors:  Benjamin Eigl; Caroline Haslebacher; Philip C Muller; Andreas Andreou; Beat Gloor; Matthias Peterhans
Journal:  IEEE Open J Eng Med Biol       Date:  2020-06-03

6.  Synthesis and characterisation of a cancerous liver for presurgical planning and training applications.

Authors:  Richard Arm; Arash Shahidi; Christopher Clarke; Edward Alabraba
Journal:  BMJ Open Gastroenterol       Date:  2022-07

7.  Patient-Specific Polyvinyl Alcohol Phantom Fabrication with Ultrasound and X-Ray Contrast for Brain Tumor Surgery Planning.

Authors:  Eleanor C Mackle; Jonathan Shapey; Efthymios Maneas; Shakeel R Saeed; Robert Bradford; Sebastien Ourselin; Tom Vercauteren; Adrien E Desjardins
Journal:  J Vis Exp       Date:  2020-07-14       Impact factor: 1.355

Review 8.  Recent advances on the development of phantoms using 3D printing for imaging with CT, MRI, PET, SPECT, and ultrasound.

Authors:  Valeria Filippou; Charalampos Tsoumpas
Journal:  Med Phys       Date:  2018-06-22       Impact factor: 4.071

9.  Soft Liver Phantom with a Hollow Biliary System.

Authors:  Xiangzhou Tan; Dandan Li; Moonkwang Jeong; Tingting Yu; Zhichao Ma; Saif Afat; Karl-Enrst Grund; Tian Qiu
Journal:  Ann Biomed Eng       Date:  2021-02-16       Impact factor: 3.934

  9 in total

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