Literature DB >> 25245730

The morbidity of negative appendicectomy.

M Lee1, T Paavana, F Mazari, T R Wilson.   

Abstract

INTRODUCTION: The increased use of diagnostic laparoscopy for management of right iliac fossa pain may have lowered the threshold for removing normal appendices, particularly as there is a perception that this practice carries little additional morbidity. The aim of this retrospective audit was to determine the negative appendicectomy rate after laparoscopic appendicectomy (LA) in our busy district hospital, and to compare the relative incidence and severity of complications after removal of an inflamed or non-inflamed appendix.
METHODS: Adult patients who underwent LA in 2011-2012 were identified from theatre registers. Histology results were reviewed to differentiate between inflamed and normal appendices. Postoperative complications and events following discharge were identified via electronic patient records. Complication severity was stratified using the Clavien-Dindo classification.
RESULTS: Over 2 years, 467 LAs were performed, of which 143 (30.6%) were for normal appendices. Significantly more negative appendicectomies were performed in women (43%) than in men (17%) (p<0.0001). Complications were seen in 62 patients (13.3%). There was no significant difference between the complication rates for those who had an inflamed (16.6%) or non-inflamed (11.9%) appendix (p=0.141). Similarly, there was no difference in the severity of complications between these groups. Reoperation or invasive intervention was required after four negative appendicectomies (2.8%).
CONCLUSIONS: LA carries a similar morbidity regardless of whether the appendix is inflamed. Negative appendicectomy should not be undertaken routinely during laparoscopy for right iliac fossa pain.

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Year:  2014        PMID: 25245730      PMCID: PMC4473437          DOI: 10.1308/003588414X13946184903801

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  16 in total

Review 1.  Laparoscopic versus open surgery for suspected appendicitis.

Authors:  Stefan Sauerland; Thomas Jaschinski; Edmund Am Neugebauer
Journal:  Cochrane Database Syst Rev       Date:  2010-10-06

2.  Implications of removing a normal appendix.

Authors:  C L Bijnen; W T Van Den Broek; A B Bijnen; P De Ruiter; D J Gouma
Journal:  Dig Surg       Date:  2003       Impact factor: 2.588

3.  Evaluation of the diagnostic accuracy of plasma markers for early diagnosis in patients suspected for acute appendicitis.

Authors:  Dirk H S M Schellekens; Karel W E Hulsewé; Bernadette A C van Acker; Annemarie A van Bijnen; Tom M H de Jaegere; Suprapto H Sastrowijoto; Wim A Buurman; Joep P M Derikx
Journal:  Acad Emerg Med       Date:  2013-07       Impact factor: 3.451

4.  Negative appendicectomy and perforation rates in patients undergoing laparoscopic surgery for suspected appendicitis.

Authors:  U Güller; L Rosella; J McCall; L E Brügger; D Candinas
Journal:  Br J Surg       Date:  2011-01-24       Impact factor: 6.939

5.  Evaluation of the appendix during diagnostic laparoscopy, the laparoscopic appendicitis score: a pilot study.

Authors:  Jenneke T H Hamminga; H Sijbrand Hofker; Paul M A Broens; Philip M Kluin; Erik Heineman; Jan Willem Haveman
Journal:  Surg Endosc       Date:  2012-10-17       Impact factor: 4.584

6.  A normal appendix found during diagnostic laparoscopy should not be removed.

Authors:  W T van den Broek; A B Bijnen; P de Ruiter; D J Gouma
Journal:  Br J Surg       Date:  2001-02       Impact factor: 6.939

Review 7.  Systematic review and meta-analysis of the diagnostic accuracy of procalcitonin, C-reactive protein and white blood cell count for suspected acute appendicitis.

Authors:  C-W Yu; L-I Juan; M-H Wu; C-J Shen; J-Y Wu; C-C Lee
Journal:  Br J Surg       Date:  2012-11-30       Impact factor: 6.939

8.  The clinical and economic correlates of misdiagnosed appendicitis: nationwide analysis.

Authors:  David R Flum; Thomas Koepsell
Journal:  Arch Surg       Date:  2002-07

9.  The impact of evolving management strategies on negative appendicectomy rate.

Authors:  E Myers; D O Kavanagh; H Ghous; D Evoy; E W McDermott
Journal:  Colorectal Dis       Date:  2010-08       Impact factor: 3.788

10.  Multicentre observational study of performance variation in provision and outcome of emergency appendicectomy.

Authors: 
Journal:  Br J Surg       Date:  2013-08       Impact factor: 6.939

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  14 in total

1.  Acute Appendicitis in the Adult Population: Modelled Decision Analysis Supports a Conservative Approach.

Authors:  Jarlath Christopher Bolger; Michael Eamon Kelly; Kevin Barry
Journal:  J Gastrointest Surg       Date:  2015-09-11       Impact factor: 3.452

2.  Delaying surgery to perform CT scans for suspected appendicitis decreases the rate of negative appendectomies without increasing the rate of perforation nor postoperative complications.

Authors:  M-O Sauvain; K Slankamenac; M K Muller; S Wildi; U Metzger; W Schmid; J Wydler; P-A Clavien; D Hahnloser
Journal:  Langenbecks Arch Surg       Date:  2016-05-04       Impact factor: 3.445

3.  The Unacceptable Morbidity of Negative Laparoscopic Appendicectomy.

Authors:  Matthew G R Allaway; Guy D Eslick; Michael R Cox
Journal:  World J Surg       Date:  2019-02       Impact factor: 3.352

Review 4.  WSES Jerusalem guidelines for diagnosis and treatment of acute appendicitis.

Authors:  Salomone Di Saverio; Arianna Birindelli; Micheal D Kelly; Fausto Catena; Dieter G Weber; Massimo Sartelli; Michael Sugrue; Mark De Moya; Carlos Augusto Gomes; Aneel Bhangu; Ferdinando Agresta; Ernest E Moore; Kjetil Soreide; Ewen Griffiths; Steve De Castro; Jeffry Kashuk; Yoram Kluger; Ari Leppaniemi; Luca Ansaloni; Manne Andersson; Federico Coccolini; Raul Coimbra; Kurinchi S Gurusamy; Fabio Cesare Campanile; Walter Biffl; Osvaldo Chiara; Fred Moore; Andrew B Peitzman; Gustavo P Fraga; David Costa; Ronald V Maier; Sandro Rizoli; Zsolt J Balogh; Cino Bendinelli; Roberto Cirocchi; Valeria Tonini; Alice Piccinini; Gregorio Tugnoli; Elio Jovine; Roberto Persiani; Antonio Biondi; Thomas Scalea; Philip Stahel; Rao Ivatury; George Velmahos; Roland Andersson
Journal:  World J Emerg Surg       Date:  2016-07-18       Impact factor: 5.469

5.  LAPAROSCOPIC APPENDECTOMY DOES NOT INCREASE THE RATE OF NEGATIVE APPENDECTOMY along with a lower rate of perforated appendicitis - RESULTS IN 1899 PATIENTS at Zagreb UHC.

Authors:  Goran Augustin; Zrinka Čižmešija; Jurica Žedelj; Igor Petrović; Vanja Ivković; Anko Antabak; Davor Mijatović; Mate Škegro
Journal:  Acta Clin Croat       Date:  2018-09       Impact factor: 0.932

6.  Accuracy of Mean Platelet Volume (MPV) and Red Cell Distribution Width (RDW) for the Diagnosis of Acute Appendicitis: Evaluation of Possible New Biomarkers.

Authors:  Alireza Rastgoo Haghi; Parvin Pourmohammad; Mohammad Ali Seyf Rabiee
Journal:  Adv J Emerg Med       Date:  2019-08-20

7.  Randomized control trial comparing an Alvarado Score-based management algorithm and current best practice in the evaluation of suspected appendicitis.

Authors:  Winson Jianhong Tan; Sanchalika Acharyya; Min Hoe Chew; Fung Joon Foo; Weng Hoong Chan; Wai Keong Wong; London Lucien Ooi; Jeremy Chung Fai Ng; Hock Soo Ong
Journal:  World J Emerg Surg       Date:  2020-05-01       Impact factor: 5.469

Review 8.  The SIFIPAC/WSES/SICG/SIMEU guidelines for diagnosis and treatment of acute appendicitis in the elderly (2019 edition).

Authors:  Paola Fugazzola; Marco Ceresoli; Vanni Agnoletti; Ferdinando Agresta; Bruno Amato; Paolo Carcoforo; Fausto Catena; Osvaldo Chiara; Massimo Chiarugi; Lorenzo Cobianchi; Federico Coccolini; Alessandro De Troia; Salomone Di Saverio; Andrea Fabbri; Carlo Feo; Francesco Gabrielli; Angela Gurrado; Angelo Guttadauro; Leonardo Leone; Daniele Marrelli; Luca Petruzzelli; Nazario Portolani; Francesco Paolo Prete; Alessandro Puzziello; Massimo Sartelli; Giorgio Soliani; Mario Testini; Salvatore Tolone; Matteo Tomasoni; Gregorio Tugnoli; Pierluigi Viale; Monica Zese; Offir Ben Ishay; Yoram Kluger; Andrew Kirkpatrick; Luca Ansaloni
Journal:  World J Emerg Surg       Date:  2020-03-10       Impact factor: 5.469

Review 9.  Evaluation of appendicitis risk prediction models in adults with suspected appendicitis.

Authors:  A Bhangu
Journal:  Br J Surg       Date:  2019-12-03       Impact factor: 6.939

10.  Computerized tomography scan in acute appendicitis with eventual negative appendectomy.

Authors:  Ming Li Chia; Kwan Justin; Hui Terrence Chi Hong; G Shelat Vishal
Journal:  J Clin Transl Res       Date:  2021-05-27
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