Kie Tae Kwon1, Adam B Kerr1, Holden H Wu2, Bob S Hu1,3, Jean H Brittain4, Dwight G Nishimura1. 1. Department of Electrical Engineering, Magnetic Resonance Systems Research Laboratory, Stanford University, Stanford, California, USA. 2. Department of Radiological Sciences, University of California at Los Angeles, Los Angeles, California, USA. 3. Palo Alto Medical Foundation, Palo Alto, California, USA. 4. Department of Radiology, University of Wisconsin-Madison, Wisconsin, USA.
Abstract
PURPOSE: To develop a new sequence for non-contrast-enhanced peripheral angiography using a sliding interleaved cylinder (SLINCYL) acquisition. METHODS: A venous saturation pulse was incorporated into a three-dimensional magnetization-prepared balanced steady-state free precession sequence for non-contrast-enhanced peripheral angiography to improve artery-vein contrast. The SLINCYL acquisition, which consists of a series of overlapped thin slabs for volumetric coverage similar to the original sliding interleaved ky (SLINKY) acquisition, was used to evenly distribute the venous-suppression effects over the field of view. In addition, the thin-slab-scan nature of SLINCYL and the centric-ordered sampling geometry of its readout trajectory were exploited to implement efficient fluid-suppression and parallel imaging schemes. The sequence was tested in healthy subjects and a patient. RESULTS: Compared to a multiple overlapped thin slab acquisition, both SLINKY and SLINCYL suppressed the venetian blind artifacts and provided similar artery-vein contrast. However, SLINCYL achieved this with shorter scan times and less noticeable artifacts from k-space amplitude modulation than SLINKY. The fluid-suppression and parallel imaging schemes were also validated. A patient study using the SLINCYL-based sequence well identified stenoses at the superficial femoral arteries, which were also confirmed with digital subtraction angiography. CONCLUSION: Non-contrast-enhanced angiography using SLINCYL can provide angiograms with improved artery-vein contrast in the lower extremities.
PURPOSE: To develop a new sequence for non-contrast-enhanced peripheral angiography using a sliding interleaved cylinder (SLINCYL) acquisition. METHODS: A venous saturation pulse was incorporated into a three-dimensional magnetization-prepared balanced steady-state free precession sequence for non-contrast-enhanced peripheral angiography to improve artery-vein contrast. The SLINCYL acquisition, which consists of a series of overlapped thin slabs for volumetric coverage similar to the original sliding interleaved ky (SLINKY) acquisition, was used to evenly distribute the venous-suppression effects over the field of view. In addition, the thin-slab-scan nature of SLINCYL and the centric-ordered sampling geometry of its readout trajectory were exploited to implement efficient fluid-suppression and parallel imaging schemes. The sequence was tested in healthy subjects and a patient. RESULTS: Compared to a multiple overlapped thin slab acquisition, both SLINKY and SLINCYL suppressed the venetian blind artifacts and provided similar artery-vein contrast. However, SLINCYL achieved this with shorter scan times and less noticeable artifacts from k-space amplitude modulation than SLINKY. The fluid-suppression and parallel imaging schemes were also validated. A patient study using the SLINCYL-based sequence well identified stenoses at the superficial femoral arteries, which were also confirmed with digital subtraction angiography. CONCLUSION: Non-contrast-enhanced angiography using SLINCYL can provide angiograms with improved artery-vein contrast in the lower extremities.
Authors: Garry E Gold; Eric Han; Jeff Stainsby; Graham Wright; Jean Brittain; Christopher Beaulieu Journal: AJR Am J Roentgenol Date: 2004-08 Impact factor: 3.959
Authors: Florian Wolf; Christina Plank; Dietrich Beitzke; Martin Popovic; Christoph M Domenig; Michael Weber; Christian Loewe Journal: AJR Am J Roentgenol Date: 2011-11 Impact factor: 3.959
Authors: Kie Tae Kwon; Holden H Wu; Taehoon Shin; Tolga Cukur; Michael Lustig; Dwight G Nishimura Journal: Magn Reson Med Date: 2013-07-01 Impact factor: 4.668