| Literature DB >> 2516928 |
Abstract
We measured the cytoplasmic free Ca concentration in the outer segment of intact, dark-adapted rods of the toad retina. The Ca indicator dye, Quin2, was loaded at concentrations of 0.273 +/- 0.06 mM into the rod cytoplasm by incubation of isolated retinas in the hydrophobic ester, Quin2AM. Quin2 did not alter the cytoplasmic Ca concentration in the dark, but it buffered light-dependent concentration transients and, hence, modified the rod photoresponse. In the presence of 1 mM external Ca, the cytoplasmic Ca concentration in the dark was 273 +/- 129 nM.Entities:
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Year: 1989 PMID： 2516928 DOI： 10.1016/0042-6989(89)90108-9
Source DB: PubMed Journal: Vision Res ISSN： 0042-6989 Impact factor: 1.886