Literature DB >> 25085670

The devil is in the details: confidentiality challenges in the age of genetics.

Barbara J Daly1, Ashley Rosko, Shulin Zhang, Hillard M Lazarus.   

Abstract

This clinical case report illustrates the potential dilemmas that can arise from knowledge gained through genetic analysis. These conflicts require careful ethical analysis of presumed duties to protect patient privacy and maintain confidentiality, the duty to warn a second party of a health risk, and the duty of veracity. While the questions raised by genetic testing of one individual for disease that reveals potentially important information about relatives, such as risk for Huntington chorea or breast cancer, have been discussed, the continuing expansion in our capacity for sophisticated genetic analysis continues to present new and challenging situations. The resolution of this case and others like it requires close collaboration among the treatment team, geneticists, and clinical ethicists.

Entities:  

Mesh:

Year:  2015        PMID: 25085670     DOI: 10.1007/s10730-014-9245-5

Source DB:  PubMed          Journal:  HEC Forum        ISSN: 0956-2737


  18 in total

1.  Consent and confidentiality in clinical genetic practice: guidance on genetic testing and sharing genetic information.

Authors:  Anneke Lucassen; Alison Hall
Journal:  Clin Med (Lond)       Date:  2012-02       Impact factor: 2.659

2.  Meeting the growing demands of genetic research.

Authors:  Amy L McGuire; Richard A Gibbs
Journal:  J Law Med Ethics       Date:  2006       Impact factor: 1.718

3.  Genetic privacy, abandonment, and DNA dragnets: Is Fourth Amendment jurisprudence adequate?

Authors:  Holly K Fernandez
Journal:  Hastings Cent Rep       Date:  2005 Jan-Feb       Impact factor: 2.683

4.  The new genetics and informed consent: differentiating choice to preserve autonomy.

Authors:  Eline M Bunnik; Antina de Jong; Niels Nijsingh; Guido M W R de Wert
Journal:  Bioethics       Date:  2013-05-30       Impact factor: 1.898

5.  Normative theorizing about genetics.

Authors:  Colin Farrelly
Journal:  Camb Q Healthc Ethics       Date:  2013-08-06       Impact factor: 1.284

6.  Biobanking, consent, and certificates of confidentiality: does the ANPRM muddy the water?

Authors:  Brett A Williams; Leslie E Wolf
Journal:  J Law Med Ethics       Date:  2013       Impact factor: 1.718

Review 7.  The family covenant and genetic testing.

Authors:  D J Doukas; J W Berg
Journal:  Am J Bioeth       Date:  2001       Impact factor: 11.229

Review 8.  Fifty years of melphalan use in hematopoietic stem cell transplantation.

Authors:  Ulas D Bayraktar; Qaiser Bashir; Muzaffar Qazilbash; Richard E Champlin; Stefan O Ciurea
Journal:  Biol Blood Marrow Transplant       Date:  2012-08-24       Impact factor: 5.742

9.  Acute toxicities of unrelated bone marrow versus peripheral blood stem cell donation: results of a prospective trial from the National Marrow Donor Program.

Authors:  Michael A Pulsipher; Pintip Chitphakdithai; Brent R Logan; Bronwen E Shaw; John R Wingard; Hillard M Lazarus; Edmund K Waller; Matthew Seftel; David F Stroncek; Angela M Lopez; Dipnarine Maharaj; Peiman Hematti; Paul V O'Donnell; Alison W Loren; Susan F Leitman; Paolo Anderlini; Steven C Goldstein; John E Levine; Willis H Navarro; John P Miller; Dennis L Confer
Journal:  Blood       Date:  2012-10-29       Impact factor: 22.113

10.  Lenalidomide after stem-cell transplantation for multiple myeloma.

Authors:  Philip L McCarthy; Kouros Owzar; Craig C Hofmeister; David D Hurd; Hani Hassoun; Paul G Richardson; Sergio Giralt; Edward A Stadtmauer; Daniel J Weisdorf; Ravi Vij; Jan S Moreb; Natalie Scott Callander; Koen Van Besien; Teresa Gentile; Luis Isola; Richard T Maziarz; Don A Gabriel; Asad Bashey; Heather Landau; Thomas Martin; Muzaffar H Qazilbash; Denise Levitan; Brian McClune; Robert Schlossman; Vera Hars; John Postiglione; Chen Jiang; Elizabeth Bennett; Susan Barry; Linda Bressler; Michael Kelly; Michele Seiler; Cara Rosenbaum; Parameswaran Hari; Marcelo C Pasquini; Mary M Horowitz; Thomas C Shea; Steven M Devine; Kenneth C Anderson; Charles Linker
Journal:  N Engl J Med       Date:  2012-05-10       Impact factor: 91.245

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.