Literature DB >> 25061900

Developing microphysiological systems for use as regulatory tools--challenges and opportunities.

Melvin E Andersen1, Kellyn Betts, Yvonne Dragan, Suzanne Fitzpatrick, Jesse L Goodman, Thomas Hartung, Jonathan Himmelfarb, Donald E Ingber, Abigail Jacobs, Robert Kavlock, Kyle Kolaja, James L Stevens, Dan Tagle, D Lansing Taylor, Douglas Throckmorton.   

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Year:  2014        PMID： 25061900      PMCID： PMC4778746          DOI： 10.14573/altex.1405151

Source DB:  PubMed          Journal:  ALTEX        ISSN： 1868-596X            Impact factor:   6.043


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  6 in total

Review 1.  Can the pharmaceutical industry reduce attrition rates?

Authors:  Ismail Kola; John Landis
Journal:  Nat Rev Drug Discov       Date:  2004-08       Impact factor: 84.694

2.  Reconstituting organ-level lung functions on a chip.

Authors:  Dongeun Huh; Benjamin D Matthews; Akiko Mammoto; Martín Montoya-Zavala; Hong Yuan Hsin; Donald E Ingber
Journal:  Science       Date:  2010-06-25       Impact factor: 47.728

3.  Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation.

Authors:  Hyun Jung Kim; Donald E Ingber
Journal:  Integr Biol (Camb)       Date:  2013-09       Impact factor: 2.192

4.  Trial watch: Phase II failures: 2008-2010.

Authors:  John Arrowsmith
Journal:  Nat Rev Drug Discov       Date:  2011-05       Impact factor: 84.694

5.  Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow.

Authors:  Hyun Jung Kim; Dongeun Huh; Geraldine Hamilton; Donald E Ingber
Journal:  Lab Chip       Date:  2012-03-20       Impact factor: 6.799

6.  A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice.

Authors:  Dongeun Huh; Daniel C Leslie; Benjamin D Matthews; Jacob P Fraser; Samuel Jurek; Geraldine A Hamilton; Kevin S Thorneloe; Michael Allen McAlexander; Donald E Ingber
Journal:  Sci Transl Med       Date:  2012-11-07       Impact factor: 17.956
  6 in total
  10 in total

1.  21st Century Cell Culture for 21st Century Toxicology.

Authors:  David Pamies; Thomas Hartung
Journal:  Chem Res Toxicol       Date:  2016-12-05       Impact factor: 3.739

2.  Systems Toxicology: The Future of Risk Assessment.

Authors:  John Michael Sauer; Thomas Hartung; Marcel Leist; Thomas B Knudsen; Julia Hoeng; A Wallace Hayes
Journal:  Int J Toxicol       Date:  2015-03-23       Impact factor: 2.032

3.  Microphysiological Systems Evaluation: Experience of TEX-VAL Tissue Chip Testing Consortium.

Authors:  Ivan Rusyn; Courtney Sakolish; Yuki Kato; Clifford Stephan; Leoncio Vergara; Philip Hewitt; Vasanthi Bhaskaran; Myrtle Davis; Rhiannon N Hardwick; Stephen S Ferguson; Jason P Stanko; Piyush Bajaj; Karissa Adkins; Nisha S Sipes; E Sidney Hunter; Maria T Baltazar; Paul L Carmichael; Kritika Sadh; Richard A Becker
Journal:  Toxicol Sci       Date:  2022-07-28       Impact factor: 4.109

Review 4.  Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function.

Authors:  S Y Chang; E J Weber; Kp Van Ness; D L Eaton; E J Kelly
Journal:  Clin Pharmacol Ther       Date:  2016-08-27       Impact factor: 6.875

Review 5.  Perspectives on In Vitro to In Vivo Extrapolations.

Authors:  Thomas Hartung
Journal:  Appl In Vitro Toxicol       Date:  2018-12-08

Review 6.  Comparison of methods used for evaluation of mutagenicity/genotoxicity of model chemicals - parabens.

Authors:  J Chrz; B Hošíková; L Svobodová; D Očadlíková; H Kolářová; M Dvořáková; K Kejlová; L Malina; G Jírová; A Vlková; M Mannerström
Journal:  Physiol Res       Date:  2020-12-31       Impact factor: 1.881

7.  Toxicity testing in the 21st century beyond environmental chemicals.

Authors:  Costanza Rovida; Shoji Asakura; Mardas Daneshian; Hana Hofman-Huether; Marcel Leist; Leo Meunier; David Reif; Anna Rossi; Markus Schmutz; Jean-Pierre Valentin; Joanne Zurlo; Thomas Hartung
Journal:  ALTEX       Date:  2015       Impact factor: 6.043

8.  A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity.

Authors:  David Pamies; Paula Barreras; Katharina Block; Georgia Makri; Anupama Kumar; Daphne Wiersma; Lenna Smirnova; Ce Zang; Joseph Bressler; Kimberly M Christian; Georgina Harris; Guo-Li Ming; Cindy J Berlinicke; Kelly Kyro; Hongjun Song; Carlos A Pardo; Thomas Hartung; Helena T Hogberg
Journal:  ALTEX       Date:  2016-11-24       Impact factor: 6.043

9.  3S - Systematic, systemic, and systems biology and toxicology.

Authors:  Lena Smirnova; Nicole Kleinstreuer; Raffaella Corvi; Andre Levchenko; Suzanne C Fitzpatrick; Thomas Hartung
Journal:  ALTEX       Date:  2018       Impact factor: 6.043

10.  Chlorpyrifos Disrupts Acetylcholine Metabolism Across Model Blood-Brain Barrier.

Authors:  Dusty R Miller; Ethan S McClain; James N Dodds; Andrzej Balinski; Jody C May; John A McLean; David E Cliffel
Journal:  Front Bioeng Biotechnol       Date:  2021-08-27
  10 in total

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