Literature DB >> 21532551

Trial watch: Phase II failures: 2008-2010.

John Arrowsmith.   

Abstract

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Year:  2011        PMID： 21532551     DOI： 10.1038/nrd3439

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  177 in total

1.  Reinventing clinical trials.

Authors:  Malorye Allison
Journal:  Nat Biotechnol       Date:  2012-01-09       Impact factor: 54.908

2.  Expanding precompetitive space.

Authors: 
Journal:  Nat Rev Drug Discov       Date:  2011-12       Impact factor: 84.694

3.  A decade of change.

Authors:  John Arrowsmith
Journal:  Nat Rev Drug Discov       Date:  2012-01-03       Impact factor: 84.694

Review 4.  Stable isotope-resolved metabolomics and applications for drug development.

Authors:  Teresa W-M Fan; Pawel K Lorkiewicz; Katherine Sellers; Hunter N B Moseley; Richard M Higashi; Andrew N Lane
Journal:  Pharmacol Ther       Date:  2011-12-23       Impact factor: 12.310

5.  Integrating pharmacology and clinical pharmacology in pharmaceutical companies.

Authors:  Jackie A Hunter
Journal:  Br J Clin Pharmacol       Date:  2012-06       Impact factor: 4.335

6.  Developing and delivering clinical pharmacology in pharmaceutical companies.

Authors:  Duncan Richards
Journal:  Br J Clin Pharmacol       Date:  2012-06       Impact factor: 4.335

7.  Drug candidates derailed in case of mistaken identity.

Authors:  Heidi Ledford
Journal:  Nature       Date:  2012-03-28       Impact factor: 49.962

Review 8.  The influence of the 'organizational factor' on compound quality in drug discovery.

Authors:  Paul D Leeson; Stephen A St-Gallay
Journal:  Nat Rev Drug Discov       Date:  2011-09-30       Impact factor: 84.694

9.  Reflections on the Adaptive Designs Accelerating Promising Trials Into Treatments (ADAPT-IT) Process-Findings from a Qualitative Study.

Authors:  Timothy C Guetterman; Michael D Fetters; Laurie J Legocki; Samkeliso Mawocha; William G Barsan; Roger J Lewis; Donald A Berry; William J Meurer
Journal:  Clin Res Regul Aff       Date:  2015-09-18

Review 10.  Molecular deconstruction, detection, and computational prediction of microenvironment-modulated cellular responses to cancer therapeutics.

Authors:  Mark A Labarge; Bahram Parvin; James B Lorens
Journal:  Adv Drug Deliv Rev       Date:  2014-02-26       Impact factor: 15.470
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