Literature DB >> 25047008

Timing properties of phosphor-coated polished LSO crystals.

Jeffrey P Schmall1, Emilie Roncali, Eric Berg, Varsha Viswanath, Junwei Du, Simon R Cherry.   

Abstract

This study investigates a time-of-flight (TOF)-depth-of-interaction (DOI) detector design for positron emission tomography (PET), based on phosphor-coated lutetium oxyorthosilicate (LSO) scintillator crystals coupled to fast single channel photomultiplier tubes. Interaction of the scintillation light with the phosphor coating changes the pulse shape in a depth-dependent manner. 3 × 3 × 10 mm(3) LSO scintillation crystals with polished surfaces were characterized, with and without phosphor coating, to assess DOI capability and timing properties. Two different phosphor coating geometries were studied: coating of the top surface of the crystal, and the top plus half of the crystal sides. There was negligible depth dependency in the decay time when coating only the top surface, however there was a ∼10 ns difference in end-to-end decay time when coating the top plus half of the crystal sides, sufficient to support the use of three DOI bins (3.3 mm DOI bin width). The rise time of the half-coated phosphor crystal was slightly faster at all depths, compared to uncoated crystals, however the signal amplitude was lower. Phosphor coating resulted in depth-dependent photopeak positions with an energy resolution of 13.7%, at a depth of 1 mm, and 15.3%, at a depth of 9 mm, for the half-coated crystal. Uncoated LSO crystals showed no change in photopeak position as a function of depth, with an energy resolution of 10.4%. The head-on coincidence timing resolution (CTR) of two uncoated LSO crystals was 287 ps using constant fraction discrimination for time pick-off. With phosphor coating, the CTR of the top-coated crystal was 314 ps, compared to 384 ps for the half-coated crystal. We demonstrate that the trade-off between timing resolution and DOI resolution can be controlled by the phosphor coating geometry. Here we present preliminary results demonstrating that good DOI resolution can be achieved with only a modest 26% degradation in CTR.

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Year:  2014        PMID: 25047008     DOI: 10.1088/0031-9155/59/15/N139

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  7 in total

Review 1.  Innovations in Instrumentation for Positron Emission Tomography.

Authors:  Eric Berg; Simon R Cherry
Journal:  Semin Nucl Med       Date:  2018-03-12       Impact factor: 4.446

2.  Reaching 200-ps timing resolution in a time-of-flight and depth-of-interaction positron emission tomography detector using phosphor-coated crystals and high-density silicon photomultipliers.

Authors:  Sun Il Kwon; Alessandro Ferri; Alberto Gola; Eric Berg; Claudio Piemonte; Simon R Cherry; Emilie Roncali
Journal:  J Med Imaging (Bellingham)       Date:  2016-11-23

3.  Dual-ended readout of bismuth germanate to improve timing resolution in time-of-flight PET.

Authors:  Sun Il Kwon; Emilie Roncali; Alberto Gola; Giovanni Paternoster; Claudio Piemonte; Simon R Cherry
Journal:  Phys Med Biol       Date:  2019-05-10       Impact factor: 3.609

4.  Characterization of stacked-crystal PET detector designs for measurement of both TOF and DOI.

Authors:  Jeffrey P Schmall; Suleman Surti; Joel S Karp
Journal:  Phys Med Biol       Date:  2015-04-10       Impact factor: 3.609

5.  Parallax error in long-axial field-of-view PET scanners-a simulation study.

Authors:  Jeffrey P Schmall; Joel S Karp; Matt Werner; Suleman Surti
Journal:  Phys Med Biol       Date:  2016-07-01       Impact factor: 3.609

6.  Improving Depth, Energy and Timing Estimation in PET Detectors with Deconvolution and Maximum Likelihood Pulse Shape Discrimination.

Authors:  Eric Berg; Emilie Roncali; Will Hutchcroft; Jinyi Qi; Simon R Cherry
Journal:  IEEE Trans Med Imaging       Date:  2016-06-07       Impact factor: 10.048

7.  A combined time-of-flight and depth-of-interaction detector for total-body positron emission tomography.

Authors:  Eric Berg; Emilie Roncali; Maciej Kapusta; Junwei Du; Simon R Cherry
Journal:  Med Phys       Date:  2016-02       Impact factor: 4.071

  7 in total

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