Literature DB >> 2501665

Expression of raf oncogenes activates the PEA1 transcription factor motif.

C Wasylyk1, B Wasylyk, G Heidecker, M Huleihel, U R Rapp.   

Abstract

PEA1 (AP1) motif transcription enhancer activity was stimulated by v-raf and more efficiently by activated c-raf-1 or A-raf than by their normal counterparts, in agreement with a role for PEA1 in transformation by raf. Mutations in the ATP-binding site of v-raf prevented activation, suggesting that phosphorylation is somehow required.

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Year:  1989        PMID： 2501665      PMCID： PMC363023          DOI： 10.1128/mcb.9.5.2247-2250.1989

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  21 in total

1.  The c-Ha-ras oncogene and a tumor promoter activate the polyoma virus enhancer.

Authors:  C Wasylyk; J L Imler; J Perez-Mutul; B Wasylyk
Journal:  Cell       Date:  1987-02-13       Impact factor: 41.582

2.  Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor.

Authors:  P Angel; M Imagawa; R Chiu; B Stein; R J Imbra; H J Rahmsdorf; C Jonat; P Herrlich; M Karin
Journal:  Cell       Date:  1987-06-19       Impact factor: 41.582

3.  Avian sarcoma virus 17 carries the jun oncogene.

Authors:  Y Maki; T J Bos; C Davis; M Starbuck; P K Vogt
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

4.  Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements.

Authors:  W Lee; P Mitchell; R Tjian
Journal:  Cell       Date:  1987-06-19       Impact factor: 41.582

5.  The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus.

Authors:  T W Beck; M Huleihel; M Gunnell; T I Bonner; U R Rapp
Journal:  Nucleic Acids Res       Date:  1987-01-26       Impact factor: 16.971

6.  Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity.

Authors:  D K Morrison; D R Kaplan; U Rapp; T M Roberts
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

7.  Characterization of murine A-raf, a new oncogene related to the v-raf oncogene.

Authors:  M Huleihel; M Goldsborough; J Cleveland; M Gunnell; T Bonner; U R Rapp
Journal:  Mol Cell Biol       Date:  1986-07       Impact factor: 4.272

8.  Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus.

Authors:  U R Rapp; M D Goldsborough; G E Mark; T I Bonner; J Groffen; F H Reynolds; J R Stephenson
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

9.  The immunoglobulin heavy-chain B-lymphocyte enhancer efficiently stimulates transcription in non-lymphoid cells.

Authors:  C Wasylyk; B Wasylyk
Journal:  EMBO J       Date:  1986-03       Impact factor: 11.598

10.  Requirement for c-ras proteins during viral oncogene transformation.

Authors:  M R Smith; S J DeGudicibus; D W Stacey
Journal:  Nature       Date:  1986 Apr 10-16       Impact factor: 49.962
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  42 in total

Review 1.  Natural biology of polyomavirus middle T antigen.

Authors:  K A Gottlieb; L P Villarreal
Journal:  Microbiol Mol Biol Rev       Date:  2001-06       Impact factor: 11.056

2.  Depletion of c-myc with specific antisense sequences reverses the transformed phenotype in ras oncogene-transformed NIH 3T3 cells.

Authors:  M D Sklar; E Thompson; M J Welsh; M Liebert; J Harney; H B Grossman; M Smith; E V Prochownik
Journal:  Mol Cell Biol       Date:  1991-07       Impact factor: 4.272

3.  Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73.

Authors:  T Smeal; B Binetruy; D Mercola; A Grover-Bardwick; G Heidecker; U R Rapp; M Karin
Journal:  Mol Cell Biol       Date:  1992-08       Impact factor: 4.272

4.  Molecular organization of the human Raf-1 promoter region.

Authors:  T W Beck; U Brennscheidt; G Sithanandam; J Cleveland; U R Rapp
Journal:  Mol Cell Biol       Date:  1990-07       Impact factor: 4.272

5.  Common mechanism of retrovirus activation and transduction of c-mil and c-Rmil in chicken neuroretina cells infected with Rous-associated virus type 1.

Authors:  M P Felder; A Eychène; J V Barnier; I Calogeraki; G Calothy; M Marx
Journal:  J Virol       Date:  1991-07       Impact factor: 5.103

6.  Compilation of vertebrate-encoded transcription factors.

Authors:  S Faisst; S Meyer
Journal:  Nucleic Acids Res       Date:  1992-01-11       Impact factor: 16.971

7.  The intragenic enhancer of human immunodeficiency virus type 1 contains functional AP-1 binding sites.

Authors:  C Van Lint; A Burny; E Verdin
Journal:  J Virol       Date:  1991-12       Impact factor: 5.103

8.  Mutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation.

Authors:  M L Gishizky; D Cortez; A M Pendergast
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-21       Impact factor: 11.205

9.  Ras activation of genes: Mob-1 as a model.

Authors:  P Liang; L Averboukh; W Zhu; A B Pardee
Journal:  Proc Natl Acad Sci U S A       Date:  1994-12-20       Impact factor: 11.205

10.  Raf-1 kinase targets GA-binding protein in transcriptional regulation of the human immunodeficiency virus type 1 promoter.

Authors:  E Flory; A Hoffmeyer; U Smola; U R Rapp; J T Bruder
Journal:  J Virol       Date:  1996-04       Impact factor: 5.103
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