| Literature DB >> 25001300 |
Francielli P K Jesus1, Laerte Ferreiro1, Érico S Loreto2, Maiara B Pilotto2, Aline Ludwig2, Karine Bizzi2, Juliana S M Tondolo2, Régis A Zanette2, Sydney H Alves3, Janio M Santurio4.
Abstract
We describe here the in vitro activities of azithromycin, clarithromycin, minocycline, or tigecycline alone and in combination with amphotericin B, itraconazole, terbinafine, voriconazole, anidulafungin, caspofungin, or micafungin against 30 isolates of the oomycete Pythium insidiosum. The assays were based on the CLSI M38-A2 technique and the checkerboard microdilution method. The main synergisms observed were through the combination of minocycline with amphotericin B (73.33%), itraconazole (70%), and micafungin (70%) and of clarithromycin with micafungin (73.33%).Entities:
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Year: 2014 PMID: 25001300 PMCID: PMC4135807 DOI: 10.1128/AAC.02349-14
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191