| Literature DB >> 12203186 |
John A Heath1, Timothy E Kiehn, Arthur E Brown, Michael P LaQuaglia, Laurel J Steinherz, Gonzalo Bearman, May Wong, Peter G Steinherz.
Abstract
We describe a 12-year-old boy with acute myeloid leukemia who developed pleuropericarditis while he was neutropenic and was receiving intravenously administered antibiotic and antifungal therapy for pneumonia. A KOH preparation of the purulent material from an extensive diagnostic and therapeutic pleuropericardial drainage procedure revealed multiple irregularly septate hyphae, and cultures yielded the organism Pythium insidiosum. After completing a 12-month course of intravenously administered liposomal amphotericin B (AmBisome; Fujisawa Healthcare) and itraconazole, the patient remained alive, in clinical remission, and symptom free.Entities:
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Year: 2002 PMID: 12203186 DOI: 10.1086/342303
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079