Literature DB >> 24940129

Clinical decision support alert appropriateness: a review and proposal for improvement.

Allison B McCoy1, Eric J Thomas2, Marie Krousel-Wood3, Dean F Sittig4.   

Abstract

BACKGROUND: Many healthcare providers are adopting clinical decision support (CDS) systems to improve patient safety and meet meaningful use requirements. Computerized alerts that prompt clinicians about drug-allergy, drug-drug, and drug-disease warnings or provide dosing guidance are most commonly implemented. Alert overrides, which occur when clinicians do not follow the guidance presented by the alert, can hinder improved patient outcomes.
METHODS: We present a review of CDS alerts and describe a proposal to develop novel methods for evaluating and improving CDS alerts that builds upon traditional informatics approaches. Our proposal incorporates previously described models for predicting alert overrides that utilize retrospective chart review to determine which alerts are clinically relevant and which overrides are justifiable.
RESULTS: Despite increasing implementations of CDS alerts, detailed evaluations rarely occur because of the extensive labor involved in manual chart reviews to determine alert and response appropriateness. Further, most studies have solely evaluated alert overrides that are appropriate or justifiable. Our proposal expands the use of web-based monitoring tools with an interactive dashboard for evaluating CDS alert and response appropriateness that incorporates the predictive models. The dashboard provides 2 views, an alert detail view and a patient detail view, to provide a full history of alerts and help put the patient's events in context.
CONCLUSION: The proposed research introduces several innovations to address the challenges and gaps in alert evaluations. This research can transform alert evaluation processes across healthcare settings, leading to improved CDS, reduced alert fatigue, and increased patient safety.

Entities:  

Keywords:  Decision support systems–clinical; electronic health records; medical order entry systems; medication errors; prevention and control; reminder systems

Year:  2014        PMID: 24940129      PMCID: PMC4052586     

Source DB:  PubMed          Journal:  Ochsner J        ISSN: 1524-5012


  57 in total

1.  Evaluating the effectiveness of clinical alerts: a signal detection approach.

Authors:  Mei-Sing Ong; Enrico Coiera
Journal:  AMIA Annu Symp Proc       Date:  2011-10-22

2.  Improving acceptance of computerized prescribing alerts in ambulatory care.

Authors:  Nidhi R Shah; Andrew C Seger; Diane L Seger; Julie M Fiskio; Gilad J Kuperman; Barry Blumenfeld; Elaine G Recklet; David W Bates; Tejal K Gandhi
Journal:  J Am Med Inform Assoc       Date:  2005-10-12       Impact factor: 4.497

3.  Turning off frequently overridden drug alerts: limited opportunities for doing it safely.

Authors:  Heleen van der Sijs; Jos Aarts; Teun van Gelder; Marc Berg; Arnold Vulto
Journal:  J Am Med Inform Assoc       Date:  2008-04-24       Impact factor: 4.497

4.  Increasing the detection and response to adherence problems with cardiovascular medication in primary care through computerized drug management systems: a randomized controlled trial.

Authors:  Robyn Tamblyn; Kristen Reidel; Allen Huang; Laurel Taylor; Nancy Winslade; Gillian Bartlett; Roland Grad; André Jacques; Martin Dawes; Pierre Larochelle; Alain Pinsonneault
Journal:  Med Decis Making       Date:  2009-08-12       Impact factor: 2.583

5.  Reasons provided by prescribers when overriding drug-drug interaction alerts.

Authors:  Amy J Grizzle; Maysaa H Mahmood; Yu Ko; John E Murphy; Edward P Armstrong; Grant H Skrepnek; William N Jones; Gregory P Schepers; W Paul Nichol; Antoun Houranieh; Donna C Dare; Christopher T Hoey; Daniel C Malone
Journal:  Am J Manag Care       Date:  2007-10       Impact factor: 2.229

6.  Development and evaluation of a comprehensive clinical decision support taxonomy: comparison of front-end tools in commercial and internally developed electronic health record systems.

Authors:  Adam Wright; Dean F Sittig; Joan S Ash; Joshua Feblowitz; Seth Meltzer; Carmit McMullen; Ken Guappone; Jim Carpenter; Joshua Richardson; Linas Simonaitis; R Scott Evans; W Paul Nichol; Blackford Middleton
Journal:  J Am Med Inform Assoc       Date:  2011-03-17       Impact factor: 4.497

7.  Validation of an association rule mining-based method to infer associations between medications and problems.

Authors:  A Wright; A McCoy; S Henkin; M Flaherty; D Sittig
Journal:  Appl Clin Inform       Date:  2013-03-06       Impact factor: 2.342

8.  Real-time pharmacy surveillance and clinical decision support to reduce adverse drug events in acute kidney injury: a randomized, controlled trial.

Authors:  Allison B McCoy; Zachary L Cox; Erin B Neal; Lemuel R Waitman; Neeraja B Peterson; Gautam Bhave; Edward D Siew; Ioana Danciu; Julia B Lewis; Josh F Peterson
Journal:  Appl Clin Inform       Date:  2012-06-13       Impact factor: 2.342

9.  Frequency of inappropriate medical exceptions to quality measures.

Authors:  Stephen D Persell; Nancy C Dolan; Elisha M Friesema; Jason A Thompson; Darren Kaiser; David W Baker
Journal:  Ann Intern Med       Date:  2010-02-16       Impact factor: 25.391

10.  Role of computerized physician order entry systems in facilitating medication errors.

Authors:  Ross Koppel; Joshua P Metlay; Abigail Cohen; Brian Abaluck; A Russell Localio; Stephen E Kimmel; Brian L Strom
Journal:  JAMA       Date:  2005-03-09       Impact factor: 56.272

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  52 in total

Review 1.  Computerized Clinical Decision Support: Contributions from 2014.

Authors:  J Bouaud; V Koutkias
Journal:  Yearb Med Inform       Date:  2015-08-13

2.  Alert dwell time: introduction of a measure to evaluate interruptive clinical decision support alerts.

Authors:  Robert B McDaniel; Jonathan D Burlison; Donald K Baker; Murad Hasan; Jennifer Robertson; Christine Hartford; Scott C Howard; Andras Sablauer; James M Hoffman
Journal:  J Am Med Inform Assoc       Date:  2015-10-24       Impact factor: 4.497

3.  Cross-vendor evaluation of key user-defined clinical decision support capabilities: a scenario-based assessment of certified electronic health records with guidelines for future development.

Authors:  Allison B McCoy; Adam Wright; Dean F Sittig
Journal:  J Am Med Inform Assoc       Date:  2015-06-23       Impact factor: 4.497

4.  Potential drug-related problems detected by electronic expert support system: physicians' views on clinical relevance.

Authors:  Tora Hammar; Bodil Lidström; Göran Petersson; Yngve Gustafson; Birgit Eiermann
Journal:  Int J Clin Pharm       Date:  2015-06-06

Review 5.  Recent publications by ochsner authors.

Authors: 
Journal:  Ochsner J       Date:  2014

6.  Reducing drug prescription errors and adverse drug events by application of a probabilistic, machine-learning based clinical decision support system in an inpatient setting.

Authors:  G Segal; A Segev; A Brom; Y Lifshitz; Y Wasserstrum; E Zimlichman
Journal:  J Am Med Inform Assoc       Date:  2019-12-01       Impact factor: 4.497

7.  A Pragmatic Guide to Establishing Clinical Decision Support Governance and Addressing Decision Support Fatigue: a Case Study.

Authors:  Kensaku Kawamanto; Michael C Flynn; Polina Kukhareva; David ElHalta; Rachel Hess; Travis Gregory; Chris Walls; Angela M Wigren; Damian Borbolla; Bruce E Bray; Mary H Parsons; Brett L Clayson; Melissa S Briley; Carole H Stipelman; Dean Taylor; Carrie S King; Guilherme Del Fiol; Thomas J Reese; Charlene R Weir; Teresa Taft; Micheal B Strong
Journal:  AMIA Annu Symp Proc       Date:  2018-12-05

8.  Efficacy and unintended consequences of hard-stop alerts in electronic health record systems: a systematic review.

Authors:  Emily M Powers; Richard N Shiffman; Edward R Melnick; Andrew Hickner; Mona Sharifi
Journal:  J Am Med Inform Assoc       Date:  2018-11-01       Impact factor: 4.497

9.  Primary care provider adherence to an alert for intensification of diabetes blood pressure medications before and after the addition of a "chart closure" hard stop.

Authors:  Magaly Ramirez; Richard Maranon; Jeffery Fu; Janet S Chon; Kimberly Chen; Carol M Mangione; Gerardo Moreno; Douglas S Bell
Journal:  J Am Med Inform Assoc       Date:  2018-09-01       Impact factor: 4.497

10.  Evaluation of User-Interface Alert Displays for Clinical Decision Support Systems for Sepsis.

Authors:  Devida Long; Muge Capan; Susan Mascioli; Danielle Weldon; Ryan Arnold; Kristen Miller
Journal:  Crit Care Nurse       Date:  2018-08       Impact factor: 1.708

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