Literature DB >> 24831673

Organ shortage: the greatest challenge facing transplant medicine.

David Shafran1, Eric Kodish, Andreas Tzakis.   

Abstract

The success of organ transplantation as a treatment for end-stage organ disease has yielded a series of ethical quandaries originating from the issue of organ shortage. Scarcity of organs for transplantation necessitates formulation of just and fair allocation policies as well as ethically viable solutions to bridging the vast gap between organ supply and demand. The concept of "triage" provides a useful paradigm in which to contextualize the organ shortage issue. This entails subjugating the welfare of the individual patient for the benefit of the wider community as an ethically justified response to the challenge of scarcity.

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Year:  2014        PMID: 24831673     DOI: 10.1007/s00268-014-2639-3

Source DB:  PubMed          Journal:  World J Surg        ISSN: 0364-2313            Impact factor:   3.352


  28 in total

1.  Transplant recipient selection: peacetime vs. wartime triage.

Authors:  R Rhodes; C Miller; M Schwartz
Journal:  Camb Q Healthc Ethics       Date:  1992       Impact factor: 1.284

2.  The gift of life: ethical issues in organ transplantation.

Authors:  J F Childress
Journal:  Bull Am Coll Surg       Date:  1996-03

3.  Is presumed consent the answer to organ shortages? Yes.

Authors:  Veronica English
Journal:  BMJ       Date:  2007-05-26

4.  Principles for allocation of scarce medical interventions.

Authors:  Govind Persad; Alan Wertheimer; Ezekiel J Emanuel
Journal:  Lancet       Date:  2009-01-31       Impact factor: 79.321

5.  Ethics of a paired-kidney-exchange program.

Authors:  L F Ross; D T Rubin; M Siegler; M A Josephson; J R Thistlethwaite; E S Woodle
Journal:  N Engl J Med       Date:  1997-06-12       Impact factor: 91.245

Review 6.  Lung and heart allocation in the United States.

Authors:  M Colvin-Adams; M Valapour; M Hertz; B Heubner; K Paulson; V Dhungel; M A Skeans; L Edwards; V Ghimire; C Waller; W S Cherikh; B L Kasiske; J J Snyder; A K Israni
Journal:  Am J Transplant       Date:  2012-09-13       Impact factor: 8.086

Review 7.  Chronic kidney disease: the global challenge.

Authors:  A Meguid El Nahas; Aminu K Bello
Journal:  Lancet       Date:  2005 Jan 22-28       Impact factor: 79.321

8.  Living paid organ transplantation results in unacceptably high recipient morbidity and mortality.

Authors:  N G Inston; D Gill; A Al-Hakim; A R Ready
Journal:  Transplant Proc       Date:  2005-03       Impact factor: 1.066

9.  Organ trafficking: global solutions for a global problem.

Authors:  Tazeen H Jafar
Journal:  Am J Kidney Dis       Date:  2009-10-31       Impact factor: 8.860

10.  Organ shortage crisis: problems and possible solutions.

Authors:  G M Abouna
Journal:  Transplant Proc       Date:  2008 Jan-Feb       Impact factor: 1.066

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  13 in total

1.  Generation by somatic cell nuclear transfer of GGTA1 knockout pigs expressing soluble human TNFRI-Fc and human HO-1.

Authors:  Geon A Kim; Eun Mi Lee; Bumrae Cho; Zahid Alam; Su Jin Kim; Sanghoon Lee; Hyun Ju Oh; Jong Ik Hwang; Curie Ahn; Byeong Chun Lee
Journal:  Transgenic Res       Date:  2018-12-14       Impact factor: 2.788

2.  How to obtain and maintain favorable results after heart transplantation: keys to success?

Authors:  Johan J A Van Cleemput; Tom O M Verbelen; Lucas N L Van Aelst; Filip R L Rega
Journal:  Ann Cardiothorac Surg       Date:  2018-01

3.  Differences in time-dependent mechanical properties between extruded and molded hydrogels.

Authors:  N Ersumo; C E Witherel; K L Spiller
Journal:  Biofabrication       Date:  2016-08-22       Impact factor: 9.954

4.  Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9.

Authors:  Dong Niu; Hong-Jiang Wei; Lin Lin; Haydy George; Tao Wang; I-Hsiu Lee; Hong-Ye Zhao; Yong Wang; Yinan Kan; Ellen Shrock; Emal Lesha; Gang Wang; Yonglun Luo; Yubo Qing; Deling Jiao; Heng Zhao; Xiaoyang Zhou; Shouqi Wang; Hong Wei; Marc Güell; George M Church; Luhan Yang
Journal:  Science       Date:  2017-08-10       Impact factor: 47.728

5.  Use of genetic risks in pediatric organ transplantation listing decisions: A national survey.

Authors:  Madeline Graf; Danton Char; Andrea Hanson-Kahn; David Magnus
Journal:  Pediatr Transplant       Date:  2019-04-23

6.  Benefit in liver transplantation: a survey among medical staff, patients, medical students and non-medical university staff and students.

Authors:  Christine Englschalk; Daniela Eser; Ralf J Jox; Alexander Gerbes; Lorenz Frey; Derek A Dubay; Martin Angele; Manfred Stangl; Bruno Meiser; Jens Werner; Markus Guba
Journal:  BMC Med Ethics       Date:  2018-02-12       Impact factor: 2.652

Review 7.  Impact of Melatonin in Solid Organ Transplantation-Is It Time for Clinical Trials? A Comprehensive Review.

Authors:  Philipp Stiegler; Augustinas Bausys; Bettina Leber; Kestutis Strupas; Peter Schemmer
Journal:  Int J Mol Sci       Date:  2018-11-08       Impact factor: 5.923

Review 8.  Livestock 2.0 - genome editing for fitter, healthier, and more productive farmed animals.

Authors:  Christine Tait-Burkard; Andrea Doeschl-Wilson; Mike J McGrew; Alan L Archibald; Helen M Sang; Ross D Houston; C Bruce Whitelaw; Mick Watson
Journal:  Genome Biol       Date:  2018-11-26       Impact factor: 13.583

9.  Awareness of Religious Leaders' Fatwa and Willingness to Donate Organ.

Authors:  M Afzal Aghaee; M Dehghani; M Sadeghi; E Khaleghi
Journal:  Int J Organ Transplant Med       Date:  2015-11-01

10.  Ex Vivo Cell Therapy by Ectopic Hepatocyte Transplantation Treats the Porcine Tyrosinemia Model of Acute Liver Failure.

Authors:  Clara T Nicolas; Robert A Kaiser; Raymond D Hickey; Kari L Allen; Zeji Du; Caitlin J VanLith; Rebekah M Guthman; Bruce Amiot; Lukkana Suksanpaisan; Bing Han; Maria Giovanna Francipane; Amin Cheikhi; Huailei Jiang; Aditya Bansal; Mukesh K Pandey; Ishan Garg; Val Lowe; Aditya Bhagwate; Daniel O'Brien; Jean-Pierre A Kocher; Timothy R DeGrado; Scott L Nyberg; Eric Lagasse; Joseph B Lillegard
Journal:  Mol Ther Methods Clin Dev       Date:  2020-07-10       Impact factor: 6.698

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