Literature DB >> 24811147

Artificial pancreas (AP) clinical trial participants' acceptance of future AP technology.

Wendy C Bevier1, Serena M Fuller, Ryan P Fuller, Richard R Rubin, Eyal Dassau, Francis J Doyle, Lois Jovanovič, Howard C Zisser.   

Abstract

BACKGROUND: Artificial pancreas (AP) systems are currently an active field of diabetes research. This pilot study examined the attitudes of AP clinical trial participants toward future acceptance of the technology, having gained firsthand experience. SUBJECTS AND METHODS: After possible influencers of AP technology adoption were considered, a 34-question questionnaire was developed. The survey assessed current treatment satisfaction, dimensions of clinical trial participant motivation, and variables of the technology acceptance model (TAM). Forty-seven subjects were contacted to complete the survey. The reliability of the survey scales was tested using Cronbach's α. The relationship of the factors to the likelihood of AP technology adoption was explored using regression analysis.
RESULTS: Thirty-six subjects (76.6%) completed the survey. Of the respondents, 86.1% were either highly likely or likely to adopt the technology once available. Reliability analysis of the survey dimensions revealed good internal consistency, with scores of >0.7 for current treatment satisfaction, convenience (motivation), personal health benefit (motivation), perceived ease of use (TAM), and perceived usefulness (TAM). Linear modeling showed that future acceptance of the AP was significantly associated with TAM and the motivation variables of convenience plus the individual item benefit to others (R(2)=0.26, P=0.05). When insulin pump and continuous glucose monitor use were added, the model significance improved (R(2)=0.37, P=0.02).
CONCLUSIONS: This pilot study demonstrated that individuals with direct AP technology experience expressed high likelihood of future acceptance. Results support the factors of personal benefit, convenience, perceived usefulness, and perceived ease of use as reliable scales that suggest system adoption in this highly motivated patient population.

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Year:  2014        PMID: 24811147      PMCID: PMC4135316          DOI: 10.1089/dia.2013.0365

Source DB:  PubMed          Journal:  Diabetes Technol Ther        ISSN: 1520-9156            Impact factor:   6.118


  25 in total

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2.  Closed-loop artificial pancreas using subcutaneous glucose sensing and insulin delivery and a model predictive control algorithm: preliminary studies in Padova and Montpellier.

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Journal:  J Diabetes Sci Technol       Date:  2009-09-01

3.  Use of continuous glucose monitoring to estimate insulin requirements in patients with type 1 diabetes mellitus during a short course of prednisone.

Authors:  Wendy C Bevier; Howard C Zisser; Lois Jovanovic; Daniel A Finan; Cesar C Palerm; Dale E Seborg; Francis J Doyle
Journal:  J Diabetes Sci Technol       Date:  2008-07

4.  Quest for the artificial pancreas: combining technology with treatment.

Authors:  Rebecca A Harvey; Youqing Wang; Benyamin Grosman; Matthew W Percival; Wendy Bevier; Daniel A Finan; Howard Zisser; Dale E Seborg; Lois Jovanovic; Francis J Doyle; Eyal Dassau
Journal:  IEEE Eng Med Biol Mag       Date:  2010 Mar-Apr

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Journal:  Diabetes Technol Ther       Date:  2007-12       Impact factor: 6.118

7.  Robust parameter estimation in a model for glucose kinetics in type 1 diabetes subjects.

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Journal:  Conf Proc IEEE Eng Med Biol Soc       Date:  2006

8.  Clinical evaluation of an automated artificial pancreas using zone-model predictive control and health monitoring system.

Authors:  Rebecca A Harvey; Eyal Dassau; Wendy C Bevier; Dale E Seborg; Lois Jovanovič; Francis J Doyle; Howard C Zisser
Journal:  Diabetes Technol Ther       Date:  2014-01-28       Impact factor: 6.118

9.  Patient perspectives on personalized glucose advisory systems for type 1 diabetes management.

Authors:  Jaclyn A Shepard; Linda Gonder-Frederick; Karen Vajda; Boris Kovatchev
Journal:  Diabetes Technol Ther       Date:  2012-08-02       Impact factor: 6.118

10.  Clinical evaluation of a personalized artificial pancreas.

Authors:  Eyal Dassau; Howard Zisser; Rebecca A Harvey; Matthew W Percival; Benyamin Grosman; Wendy Bevier; Eran Atlas; Shahar Miller; Revital Nimri; Lois Jovanovic; Francis J Doyle
Journal:  Diabetes Care       Date:  2012-11-27       Impact factor: 19.112

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Review 1.  Physical activity and type 1 diabetes: time for a rewire?

Authors:  Sheri R Colberg; Remmert Laan; Eyal Dassau; David Kerr
Journal:  J Diabetes Sci Technol       Date:  2015-01-06

2.  Trust in hybrid closed loop among people with diabetes: Perspectives of experienced system users.

Authors:  Molly L Tanenbaum; Esti Iturralde; Sarah J Hanes; Sakinah C Suttiratana; Jodie M Ambrosino; Trang T Ly; David M Maahs; Diana Naranjo; Natalie Walders-Abramson; Stuart A Weinzimer; Bruce A Buckingham; Korey K Hood
Journal:  J Health Psychol       Date:  2017-07-12

Review 3.  Psychosocial assessment of artificial pancreas (AP): commentary and review of existing measures and their applicability in AP research.

Authors:  Katharine D Barnard; Korey K Hood; Jill Weissberg-Benchell; Chris Aldred; Nick Oliver; Lori Laffel
Journal:  Diabetes Technol Ther       Date:  2014-12-30       Impact factor: 6.118

4.  Psychosocial Impact of the Bionic Pancreas During Summer Camp.

Authors:  Jill Weissberg-Benchell; Danielle Hessler; William H Polonsky; Lawrence Fisher
Journal:  J Diabetes Sci Technol       Date:  2016-06-28

5.  Perceptions and expectations of adults with type 1 diabetes for the use of artificial pancreas systems with and without glucagon addition: Results of an online survey.

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Journal:  Nutr Metab Cardiovasc Dis       Date:  2020-10-17       Impact factor: 4.222

6.  Psychological outcomes of evening and night closed-loop insulin delivery under free living conditions in people with Type 1 diabetes: a 2-month randomized crossover trial.

Authors:  J Kropff; J DeJong; S Del Favero; J Place; M Messori; B Coestier; A Farret; F Boscari; S Galasso; A Avogaro; D Bruttomesso; C Cobelli; E Renard; L Magni; J H DeVries
Journal:  Diabet Med       Date:  2016-10-28       Impact factor: 4.359

7.  Acceptance of the Artificial Pancreas: Comparing the Effect of Technology Readiness, Product Characteristics, and Social Influence Between Invited and Self-Selected Respondents.

Authors:  Tamara Oukes; Helga Blauw; Arianne C van Bon; J Hans DeVries; Ariane M von Raesfeld
Journal:  J Diabetes Sci Technol       Date:  2019-01-15

8.  Response to comment on Doyle et al. Closed-loop artificial pancreas systems: engineering the algorithms. Diabetes Care 2014;37:1191-1197.

Authors:  Francis J Doyle; Lauren M Huyett; Joon Bok Lee; Howard C Zisser; David Kerr; Eyal Dassau
Journal:  Diabetes Care       Date:  2014-10       Impact factor: 19.112

  8 in total

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