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Literature DB >> 2475854

DNA curvature in front of the human mitochondrial L-strand replication origin with specific protein binding.

Abstract

DNA bending has been suggested to play a role in the regulation of gene expression, initiation of DNA-replication, site specific recombination, and DNA packaging. In the human mitochondrial DNA we have found a DNA curvature structure within the 3'-region of ther URF2 sequence in front of the L-strand origin of replication. This structure interacts specifically with a protein factor isolated from mitochondria. Based on the localization of this DNA curvature structure and the known function of such structures the data suggest a model in which this DNA signal sequence and its specific protein binding is involved in the regulatory initiation event of L-strand replication.

Entities: Gene Species

Mesh：

Substances：

Year: 1989 PMID： 2475854 PMCID： PMC318262 DOI： 10.1093/nar/17.15.6077

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

47 in total

1. Inducible binding of a factor to the c-fos enhancer.

Authors: R Prywes; R G Roeder
Journal: Cell Date: 1986-12-05 Impact factor: 41.582

2. Sequence-induced DNA curvature at the bacteriophage lambda origin of replication.

Authors: K Zahn; F R Blattner
Journal: Nature Date: 1985 Oct 3-9 Impact factor: 49.962

3. Use of a protein-blotting procedure and a specific DNA probe to identify nuclear proteins that recognize the promoter region of the transferrin receptor gene.

Authors: W K Miskimins; M P Roberts; A McClelland; F H Ruddle
Journal: Proc Natl Acad Sci U S A Date: 1985-10 Impact factor: 11.205

4. DNA primase of human mitochondria is associated with structural RNA that is essential for enzymatic activity.

Authors: T W Wong; D A Clayton
Journal: Cell Date: 1986-06-20 Impact factor: 41.582

5. Detection, sequence patterns and function of unusual DNA structures.

Authors: J N Anderson
Journal: Nucleic Acids Res Date: 1986-11-11 Impact factor: 16.971

6. Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors: U K Laemmli
Journal: Nature Date: 1970-08-15 Impact factor: 49.962

Review 7. Curved DNA.

Authors: E N Trifonov
Journal: CRC Crit Rev Biochem Date: 1985

8. Sequence and organization of the human mitochondrial genome.

Authors: S Anderson; A T Bankier; B G Barrell; M H de Bruijn; A R Coulson; J Drouin; I C Eperon; D P Nierlich; B A Roe; F Sanger; P H Schreier; A J Smith; R Staden; I G Young
Journal: Nature Date: 1981-04-09 Impact factor: 49.962

9. Unique poly(dA).poly(dT) B'-conformation in cellular and synthetic DNAs.

Authors: S Diekmann; D A Zarling
Journal: Nucleic Acids Res Date: 1987-08-11 Impact factor: 16.971

10. Nucleosome reconstitution on plasmid-inserted poly(dA) . poly(dT).

Authors: A Prunell
Journal: EMBO J Date: 1982 Impact factor: 11.598

8 in total

1. The sequence-directed bent DNA detected in the replication origin of Chlamydomonas reinhardtii chloroplast DNA is important for the replication function.

Authors: C H Hsieh; M Wu; J M Yang
Journal: Mol Gen Genet Date: 1991-01

Review 2. Potential genetic functions of tandem repeated DNA sequence blocks in the human genome are based on a highly conserved "chromatin folding code".

Authors: P Vogt
Journal: Hum Genet Date: 1990-03 Impact factor: 4.132

3. Two distinct, sequence-specific DNA-binding proteins interact independently with the major replication pause region of sea urchin mtDNA.

Authors: S A Qureshi; H T Jacobs
Journal: Nucleic Acids Res Date: 1993-06-25 Impact factor: 16.971