Literature DB >> 7219534

Sequence and organization of the human mitochondrial genome.

S Anderson, A T Bankier, B G Barrell, M H de Bruijn, A R Coulson, J Drouin, I C Eperon, D P Nierlich, B A Roe, F Sanger, P H Schreier, A J Smith, R Staden, I G Young.   

Abstract

The complete sequence of the 16,569-base pair human mitochondrial genome is presented. The genes for the 12S and 16S rRNAs, 22 tRNAs, cytochrome c oxidase subunits I, II and III, ATPase subunit 6, cytochrome b and eight other predicted protein coding genes have been located. The sequence shows extreme economy in that the genes have none or only a few noncoding bases between them, and in many cases the termination codons are not coded in the DNA but are created post-transcriptionally by polyadenylation of the mRNAs.

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Year:  1981        PMID: 7219534     DOI: 10.1038/290457a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  2000 in total

1.  Peopling of Sahul: mtDNA variation in aboriginal Australian and Papua New Guinean populations.

Authors:  A J Redd; M Stoneking
Journal:  Am J Hum Genet       Date:  1999-09       Impact factor: 11.025

2.  The expression of several mitochondrial and nuclear genes encoding the subunits of electron transport chain enzyme complexes, cytochrome c oxidase, and NADH dehydrogenase, in different brain regions in Alzheimer's disease.

Authors:  M Y Aksenov; H M Tucker; P Nair; M V Aksenova; D A Butterfield; S Estus; W R Markesbery
Journal:  Neurochem Res       Date:  1999-06       Impact factor: 3.996

3.  Mechanisms of human mitochondrial DNA maintenance: the determining role of primary sequence and length over function.

Authors:  C T Moraes; L Kenyon; H Hao
Journal:  Mol Biol Cell       Date:  1999-10       Impact factor: 4.138

4.  Complete DNA sequence of the mitochondrial genome of the ascidian Halocynthia roretzi (Chordata, Urochordata).

Authors:  S i Yokobori; T Ueda; G Feldmaier-Fuchs; S Pääbo; R Ueshima; A Kondow; K Nishikawa; K Watanabe
Journal:  Genetics       Date:  1999-12       Impact factor: 4.562

5.  Heterogenous point mutations in the mitochondrial tRNA Ser(UCN) precursor coexisting with the A1555G mutation in deaf students from Mongolia.

Authors:  A Pandya; X J Xia; R Erdenetungalag; M Amendola; B Landa; J Radnaabazar; B Dangaasuren; G Van Tuyle; W E Nance
Journal:  Am J Hum Genet       Date:  1999-12       Impact factor: 11.025

6.  Pattern of nucleotide substitution and rate heterogeneity in the hypervariable regions I and II of human mtDNA.

Authors:  S Meyer; G Weiss; A von Haeseler
Journal:  Genetics       Date:  1999-07       Impact factor: 4.562

7.  A novel method for estimating substitution rate variation among sites in a large dataset of homologous DNA sequences.

Authors:  G Pesole; C Saccone
Journal:  Genetics       Date:  2001-02       Impact factor: 4.562

8.  Point mutations of the mtDNA control region in normal and neurodegenerative human brains.

Authors:  P F Chinnery; G A Taylor; N Howell; D T Brown; T J Parsons; D M Turnbull
Journal:  Am J Hum Genet       Date:  2000-12-21       Impact factor: 11.025

9.  The RNase P associated with HeLa cell mitochondria contains an essential RNA component identical in sequence to that of the nuclear RNase P.

Authors:  R S Puranam; G Attardi
Journal:  Mol Cell Biol       Date:  2001-01       Impact factor: 4.272

Review 10.  The final cut. The importance of tRNA 3'-processing.

Authors:  M Mörl; A Marchfelder
Journal:  EMBO Rep       Date:  2001-01       Impact factor: 8.807

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