| Literature DB >> 7219534 |
S Anderson, A T Bankier, B G Barrell, M H de Bruijn, A R Coulson, J Drouin, I C Eperon, D P Nierlich, B A Roe, F Sanger, P H Schreier, A J Smith, R Staden, I G Young.
Abstract
The complete sequence of the 16,569-base pair human mitochondrial genome is presented. The genes for the 12S and 16S rRNAs, 22 tRNAs, cytochrome c oxidase subunits I, II and III, ATPase subunit 6, cytochrome b and eight other predicted protein coding genes have been located. The sequence shows extreme economy in that the genes have none or only a few noncoding bases between them, and in many cases the termination codons are not coded in the DNA but are created post-transcriptionally by polyadenylation of the mRNAs.Entities:
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Year: 1981 PMID: 7219534 DOI: 10.1038/290457a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962