Yu-Wei Lin1, Kuei-Hua Lin2, Hsiu-Wen Ho2, Hsiu-Man Lin2, Li-Ching Lin3, Steve P Lee4, Chen-Shou Chui5. 1. Department of Radiation Oncology, Chi Mei Medical Center, Tainan, Taiwan; Institute of Biomedical Sciences, National Sun Yat-sen University, Kaohsiung, Taiwan; School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: marklin1108@gmail.com. 2. Department of Radiation Oncology, Chi Mei Medical Center, Tainan, Taiwan. 3. Department of Radiation Oncology, Chi Mei Medical Center, Tainan, Taiwan; School of Medicine, Taipei Medical University, Taipei, Taiwan. 4. Department of Radiation Oncology, David Geffen School of Medicine of The University of California Los Angeles, Los Angeles, CA, USA. 5. Department of Medical Physics, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
Abstract
PURPOSE: The aim of this study was to evaluate the feasibility and dose distribution of two different stereotactic body radiation therapy (SBRT) techniques, isocentric RapidArc (RA) and non-isocentric CyberKnife (CK), for the treatment of localized prostate cancer. METHODS: Two groups of patients (Groups 1 and 2 with ten patients per group) treated with CK were re-planned with RA. The patients were grouped according to the rectum constraint used (Group1, maximum dose for rectum; Group 2, dose-volume histogram for rectum). The prescription dose was 37.5 Gy in five fractions. The two SBRT techniques were compared by target coverage, normal tissue sparing, and dose distribution parameters. Monitor units (MUs) and the delivery time were likewise compared to assess delivery efficiency. RESULTS: The RA plans consistently exhibited superior PTV coverage and better rectum sparing at low doses in the both groups. The conformity and heterogeneity indices of the RA plans were better than the CK plans. Additionally, the RA plans resulted in fewer low-dose regions, lower MUs, and faster delivery times than the CK plans. CONCLUSIONS: The good dosimetric distribution and shorter delivery time make RA an attractive SBRT technique for the treatment of localized prostate cancer.
PURPOSE: The aim of this study was to evaluate the feasibility and dose distribution of two different stereotactic body radiation therapy (SBRT) techniques, isocentric RapidArc (RA) and non-isocentric CyberKnife (CK), for the treatment of localized prostate cancer. METHODS: Two groups of patients (Groups 1 and 2 with ten patients per group) treated with CK were re-planned with RA. The patients were grouped according to the rectum constraint used (Group1, maximum dose for rectum; Group 2, dose-volume histogram for rectum). The prescription dose was 37.5 Gy in five fractions. The two SBRT techniques were compared by target coverage, normal tissue sparing, and dose distribution parameters. Monitor units (MUs) and the delivery time were likewise compared to assess delivery efficiency. RESULTS: The RA plans consistently exhibited superior PTV coverage and better rectum sparing at low doses in the both groups. The conformity and heterogeneity indices of the RA plans were better than the CK plans. Additionally, the RA plans resulted in fewer low-dose regions, lower MUs, and faster delivery times than the CK plans. CONCLUSIONS: The good dosimetric distribution and shorter delivery time make RA an attractive SBRT technique for the treatment of localized prostate cancer.
Authors: Krzysztof Ślosarek; Wojciech Osewski; Aleksandra Grządziel; Michał Radwan; Łukasz Dolla; Marta Szlag; Małgorzata Stąpór-Fudzińska Journal: Rep Pract Oncol Radiother Date: 2014-11-18
Authors: Eun Kyung Paik; Mi-Sook Kim; Chul Won Choi; Won Il Jang; Sung Hyun Lee; Sang Hyoun Choi; Kum Bae Kim; Dong Han Lee Journal: Radiat Oncol J Date: 2015-09-30
Authors: Emil Schüler; Anthony Lo; Cynthia F Chuang; Scott G Soltys; Erqi L Pollom; Lei Wang Journal: J Appl Clin Med Phys Date: 2020-03-25 Impact factor: 2.102