Literature DB >> 24687050

Integrative knowledge management to enhance pharmaceutical R&D.

Maria Marti-Solano1, Ewan Birney2, Antoine Bril3, Oscar Della Pasqua4, Hiroaki Kitano5, Barend Mons6, Ioannis Xenarios7, Ferran Sanz1.   

Abstract

Information technologies already have a key role in pharmaceutical research and development (R&D), but achieving substantial advances in their use and effectiveness will depend on overcoming current challenges in sharing, integrating and jointly analysing the range of data generated at different stages of the R&D process.

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Year:  2014        PMID： 24687050     DOI： 10.1038/nrd4290

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


  5 in total

1.  Knowledge engineering for health: a new discipline required to bridge the "ICT gap" between research and healthcare.

Authors:  Tim Beck; Sirisha Gollapudi; Søren Brunak; Norbert Graf; Heinz U Lemke; Debasis Dash; Iain Buchan; Carlos Díaz; Ferran Sanz; Anthony J Brookes
Journal:  Hum Mutat       Date:  2012-04-04       Impact factor: 4.878

Review 2.  Open PHACTS: semantic interoperability for drug discovery.

Authors:  Antony J Williams; Lee Harland; Paul Groth; Stephen Pettifer; Christine Chichester; Egon L Willighagen; Chris T Evelo; Niklas Blomberg; Gerhard Ecker; Carole Goble; Barend Mons
Journal:  Drug Discov Today       Date:  2012-06-07       Impact factor: 7.851

3.  Improving data and knowledge management to better integrate health care and research.

Authors:  M Cases; L I Furlong; J Albanell; R B Altman; R Bellazzi; S Boyer; A Brand; A J Brookes; S Brunak; T W Clark; J Gea; P Ghazal; N Graf; R Guigó; T E Klein; N López-Bigas; V Maojo; B Mons; M Musen; J L Oliveira; A Rowe; P Ruch; A Shabo; E H Shortliffe; A Valencia; J van der Lei; M A Mayer; F Sanz
Journal:  J Intern Med       Date:  2013-07-15       Impact factor: 8.989

4.  Social engineering for virtual 'big science' in systems biology.

Authors:  Hiroaki Kitano; Samik Ghosh; Yukiko Matsuoka
Journal:  Nat Chem Biol       Date:  2011-06       Impact factor: 15.040

5.  Toward interoperable bioscience data.

Authors:  Susanna-Assunta Sansone; Philippe Rocca-Serra; Dawn Field; Eamonn Maguire; Chris Taylor; Oliver Hofmann; Hong Fang; Steffen Neumann; Weida Tong; Linda Amaral-Zettler; Kimberly Begley; Tim Booth; Lydie Bougueleret; Gully Burns; Brad Chapman; Tim Clark; Lee-Ann Coleman; Jay Copeland; Sudeshna Das; Antoine de Daruvar; Paula de Matos; Ian Dix; Scott Edmunds; Chris T Evelo; Mark J Forster; Pascale Gaudet; Jack Gilbert; Carole Goble; Julian L Griffin; Daniel Jacob; Jos Kleinjans; Lee Harland; Kenneth Haug; Henning Hermjakob; Shannan J Ho Sui; Alain Laederach; Shaoguang Liang; Stephen Marshall; Annette McGrath; Emily Merrill; Dorothy Reilly; Magali Roux; Caroline E Shamu; Catherine A Shang; Christoph Steinbeck; Anne Trefethen; Bryn Williams-Jones; Katherine Wolstencroft; Ioannis Xenarios; Winston Hide
Journal:  Nat Genet       Date:  2012-01-27       Impact factor: 38.330
  5 in total
  2 in total

1.  Key factors for successful data integration in biomarker research.

Authors:  Antigoni Elefsinioti; Tanja Bellaire; Albert Wang; Karsten Quast; Henrik Seidel; Michael Braxenthaler; Gernot Goeller; Anastasia Christianson; David Henderson; Joachim Reischl
Journal:  Nat Rev Drug Discov       Date:  2016-05-13       Impact factor: 84.694

2.  The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives.

Authors:  François Pognan; Thomas Steger-Hartmann; Carlos Díaz; Niklas Blomberg; Frank Bringezu; Katharine Briggs; Giulia Callegaro; Salvador Capella-Gutierrez; Emilio Centeno; Javier Corvi; Philip Drew; William C Drewe; José M Fernández; Laura I Furlong; Emre Guney; Jan A Kors; Miguel Angel Mayer; Manuel Pastor; Janet Piñero; Juan Manuel Ramírez-Anguita; Francesco Ronzano; Philip Rowell; Josep Saüch-Pitarch; Alfonso Valencia; Bob van de Water; Johan van der Lei; Erik van Mulligen; Ferran Sanz
Journal:  Pharmaceuticals (Basel)       Date:  2021-03-08
  2 in total

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