Literature DB >> 22392843

Knowledge engineering for health: a new discipline required to bridge the "ICT gap" between research and healthcare.

Tim Beck1, Sirisha Gollapudi, Søren Brunak, Norbert Graf, Heinz U Lemke, Debasis Dash, Iain Buchan, Carlos Díaz, Ferran Sanz, Anthony J Brookes.   

Abstract

Despite vast amount of money and research being channeled toward biomedical research, relatively little impact has been made on routine clinical practice. At the heart of this failure is the information and communication technology "chasm" that exists between research and healthcare. A new focus on "knowledge engineering for health" is needed to facilitate knowledge transmission across the research-healthcare gap. This discipline is required to engineer the bidirectional flow of data: processing research data and knowledge to identify clinically relevant advances and delivering these into healthcare use; conversely, making outcomes from the practice of medicine suitably available for use by the research community. This system will be able to self-optimize in that outcomes for patients treated by decisions that were based on the latest research knowledge will be fed back to the research world. A series of meetings, culminating in the "I-Health 2011" workshop, have brought together interdisciplinary experts to map the challenges and requirements for such a system. Here, we describe the main conclusions from these meetings. An "I4Health" interdisciplinary network of experts now exists to promote the key aims and objectives, namely "integrating and interpreting information for individualized healthcare," by developing the "knowledge engineering for health" domain.
© 2012 Wiley Periodicals, Inc.

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Year:  2012        PMID: 22392843     DOI: 10.1002/humu.22066

Source DB:  PubMed          Journal:  Hum Mutat        ISSN: 1059-7794            Impact factor:   4.878


  9 in total

1.  Improving data and knowledge management to better integrate health care and research.

Authors:  M Cases; L I Furlong; J Albanell; R B Altman; R Bellazzi; S Boyer; A Brand; A J Brookes; S Brunak; T W Clark; J Gea; P Ghazal; N Graf; R Guigó; T E Klein; N López-Bigas; V Maojo; B Mons; M Musen; J L Oliveira; A Rowe; P Ruch; A Shabo; E H Shortliffe; A Valencia; J van der Lei; M A Mayer; F Sanz
Journal:  J Intern Med       Date:  2013-07-15       Impact factor: 8.989

2.  A Review of Realizing the Universal Health Coverage (UHC) Goals by 2030: Part 2- What is the Role of eHealth and Technology?

Authors:  Rada Hussein
Journal:  J Med Syst       Date:  2015-06-05       Impact factor: 4.460

3.  Getting ready for the Human Phenome Project: the 2012 forum of the Human Variome Project.

Authors:  William S Oetting; Peter N Robinson; Marc S Greenblatt; Richard G Cotton; Tim Beck; John C Carey; Sandra C Doelken; Marta Girdea; Tudor Groza; Carol M Hamilton; Ada Hamosh; Berit Kerner; Jacqueline A L MacArthur; Donna R Maglott; Barend Mons; Heidi L Rehm; Paul N Schofield; Beverly A Searle; Damian Smedley; Cynthia L Smith; Inge Thomsen Bernstein; Andreas Zankl; Eric Y Zhao
Journal:  Hum Mutat       Date:  2013-04       Impact factor: 4.878

4.  Integrative knowledge management to enhance pharmaceutical R&D.

Authors:  Maria Marti-Solano; Ewan Birney; Antoine Bril; Oscar Della Pasqua; Hiroaki Kitano; Barend Mons; Ioannis Xenarios; Ferran Sanz
Journal:  Nat Rev Drug Discov       Date:  2014-04       Impact factor: 84.694

5.  Study of the uses of Information and Communication Technologies by Pain Treatment Unit Physicians.

Authors:  Jorge Muriel Fernandez; María José Sánchez Ledesma; Manuel López Millan; María Begoña García Cenador
Journal:  J Med Syst       Date:  2017-03-27       Impact factor: 4.460

6.  Promoting Precision Cancer Medicine through a Community-Driven Knowledgebase.

Authors:  Nophar Geifman; Izhak Haviv; Razelle Kurzrock; Eitan Rubin
Journal:  J Pers Med       Date:  2014-12-15

7.  Orchestrating differential data access for translational research: a pilot implementation.

Authors:  Marco Brandizi; Olga Melnichuk; Raffael Bild; Florian Kohlmayer; Benedicto Rodriguez-Castro; Helmut Spengler; Klaus A Kuhn; Wolfgang Kuchinke; Christian Ohmann; Timo Mustonen; Mikael Linden; Tommi Nyrönen; Ilkka Lappalainen; Alvis Brazma; Ugis Sarkans
Journal:  BMC Med Inform Decis Mak       Date:  2017-03-23       Impact factor: 2.796

Review 8.  Are innovation and new technologies in precision medicine paving a new era in patients centric care?

Authors:  Attila A Seyhan; Claudio Carini
Journal:  J Transl Med       Date:  2019-04-05       Impact factor: 5.531

Review 9.  Technology-Based Innovations to Foster Personalized Healthy Lifestyles and Well-Being: A Targeted Review.

Authors:  Emmanouil G Spanakis; Silvina Santana; Manolis Tsiknakis; Kostas Marias; Vangelis Sakkalis; António Teixeira; Joris H Janssen; Henri de Jong; Chariklia Tziraki
Journal:  J Med Internet Res       Date:  2016-06-24       Impact factor: 5.428

  9 in total

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