Literature DB >> 27173942

Key factors for successful data integration in biomarker research.

Antigoni Elefsinioti1, Tanja Bellaire1, Albert Wang2, Karsten Quast3, Henrik Seidel1, Michael Braxenthaler4, Gernot Goeller1, Anastasia Christianson2, David Henderson1, Joachim Reischl5,1.   

Abstract

Integrating a wide range of biomedical data such as that rapidly emerging from the use of next-generation sequencing is expected to have a key role in identifying and qualifying new biomarkers to support precision medicine. Here, we highlight some of the challenges for biomedical data integration and approaches to address them.

Mesh：

Substances：

Year:  2016        PMID： 27173942     DOI： 10.1038/nrd.2016.74

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


  1 in total

1.  Integrative knowledge management to enhance pharmaceutical R&D.

Authors:  Maria Marti-Solano; Ewan Birney; Antoine Bril; Oscar Della Pasqua; Hiroaki Kitano; Barend Mons; Ioannis Xenarios; Ferran Sanz
Journal:  Nat Rev Drug Discov       Date:  2014-04       Impact factor: 84.694
  1 in total
  7 in total

Review 1.  Whither systems medicine?

Authors:  Rolf Apweiler; Tim Beissbarth; Michael R Berthold; Nils Blüthgen; Yvonne Burmeister; Olaf Dammann; Andreas Deutsch; Friedrich Feuerhake; Andre Franke; Jan Hasenauer; Steve Hoffmann; Thomas Höfer; Peter Lm Jansen; Lars Kaderali; Ursula Klingmüller; Ina Koch; Oliver Kohlbacher; Lars Kuepfer; Frank Lammert; Dieter Maier; Nico Pfeifer; Nicole Radde; Markus Rehm; Ingo Roeder; Julio Saez-Rodriguez; Ulrich Sax; Bernd Schmeck; Andreas Schuppert; Bernd Seilheimer; Fabian J Theis; Julio Vera; Olaf Wolkenhauer
Journal:  Exp Mol Med       Date:  2018-03-02       Impact factor: 8.718

2.  Learning with multiple pairwise kernels for drug bioactivity prediction.

Authors:  Anna Cichonska; Tapio Pahikkala; Sandor Szedmak; Heli Julkunen; Antti Airola; Markus Heinonen; Tero Aittokallio; Juho Rousu
Journal:  Bioinformatics       Date:  2018-07-01       Impact factor: 6.937

3.  Deblender: a semi-/unsupervised multi-operational computational method for complete deconvolution of expression data from heterogeneous samples.

Authors:  Konstantina Dimitrakopoulou; Elisabeth Wik; Lars A Akslen; Inge Jonassen
Journal:  BMC Bioinformatics       Date:  2018-11-07       Impact factor: 3.169

Review 4.  Translational precision medicine: an industry perspective.

Authors:  Dominik Hartl; Valeria de Luca; Anna Kostikova; Jason Laramie; Scott Kennedy; Enrico Ferrero; Richard Siegel; Martin Fink; Sohail Ahmed; John Millholland; Alexander Schuhmacher; Markus Hinder; Luca Piali; Adrian Roth
Journal:  J Transl Med       Date:  2021-06-05       Impact factor: 5.531

5.  Empowering pharmacoinformatics by linked life science data.

Authors:  Daria Goldmann; Barbara Zdrazil; Daniela Digles; Gerhard F Ecker
Journal:  J Comput Aided Mol Des       Date:  2016-11-09       Impact factor: 4.179

Review 6.  Applications of RNA Indexes for Precision Oncology in Breast Cancer.

Authors:  Liming Ma; Zirui Liang; Hui Zhou; Lianghu Qu
Journal:  Genomics Proteomics Bioinformatics       Date:  2018-05-09       Impact factor: 7.691

7.  Presenting and sharing clinical data using the eTRIKS Standards Master Tree for tranSMART.

Authors:  Adriano Barbosa-Silva; Dorina Bratfalean; Wei Gu; Venkata Satagopam; Paul Houston; Lauren B Becnel; Serge Eifes; Fabien Richard; Andreas Tielmann; Sascha Herzinger; Kavita Rege; Rudi Balling; Paul Peeters; Reinhard Schneider
Journal:  Bioinformatics       Date:  2019-05-01       Impact factor: 6.937
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.