Anupam Saha1, Cs Naidu2, Gs Ramesh3, Joy Chatterjee4, Pankaj Puri5, Bhaskar Nandi5, Pradhi Nambiar6, Renu Madan7. 1. Commandant, Military Hospital, Agra, Agra Cantt. - 282001. 2. Senior Advisor (Surgery & GI Surgery), Army Hospital (R&R), Delhi Cantt., New Delhi - 10. 3. Consultant (CTVS Anaesthesia), Army Hospital (R&R), Delhi Cantt., New Delhi - 10. 4. Senior Advisor (Paediatric Anaesthesia), INHS Asvini, Colaba, Mumbai. 5. Senior Advisor, (Gastroenterology), Army Hospital (R&R), Delhi Cantt., New Delhi - 10. 6. Transplant Coordinator, Army Hospital (R&R), Delhi Cantt., New Delhi - 10. 7. Classified Specialist (Pathology), Army Hospital (R&R), Delhi Cantt., New Delhi - 10.
Abstract
BACKGROUND: This study retrospectively analyses the initial experience of liver transplantation (LT) in the Indian Armed Forces. METHODS: Fifty-three patients underwent LT at Army Hospital (R&R) Delhi Cantt. between March 2007 and March 2011. Of these 35 patients underwent deceased donor liver transplantation (DDLT) and living donor liver transplantation (LDLT) was carried out in 18 patients. The surgical techniques, complications and mortality were analysed. RESULTS: A high consent rate of 35.9% for organ donation was achieved by the Armed Forces Organ Retrieval and Transplantation Authority (AORTA). Biliary complications occurred in five patients (9.4%). However, most of them could be managed by endoscopic interventions. Hepatic artery thrombosis (HAT) occurred in five patients (9.4%). Of these, two DDLT grafts were revascularised following HAT, by creating extra-anatomic arterial conduits with excellent outcome. The overall mortality was 18.8% (n = 10). There was no significant difference in the overall complications or mortality in patients undergoing DDLT or LDLT. CONCLUSION: The overall survival and morbidity in this study is comparable to those from other centres. Urgent revascularisation of grafts following HAT should be attempted as it can salvage grafts with satisfactory outcome. There is a reduction in the incidence of biliary complications with refinements in surgical techniques.
BACKGROUND: This study retrospectively analyses the initial experience of liver transplantation (LT) in the Indian Armed Forces. METHODS: Fifty-three patients underwent LT at Army Hospital (R&R) Delhi Cantt. between March 2007 and March 2011. Of these 35 patients underwent deceased donor liver transplantation (DDLT) and living donor liver transplantation (LDLT) was carried out in 18 patients. The surgical techniques, complications and mortality were analysed. RESULTS: A high consent rate of 35.9% for organ donation was achieved by the Armed Forces Organ Retrieval and Transplantation Authority (AORTA). Biliary complications occurred in five patients (9.4%). However, most of them could be managed by endoscopic interventions. Hepatic artery thrombosis (HAT) occurred in five patients (9.4%). Of these, two DDLT grafts were revascularised following HAT, by creating extra-anatomic arterial conduits with excellent outcome. The overall mortality was 18.8% (n = 10). There was no significant difference in the overall complications or mortality in patients undergoing DDLT or LDLT. CONCLUSION: The overall survival and morbidity in this study is comparable to those from other centres. Urgent revascularisation of grafts following HAT should be attempted as it can salvage grafts with satisfactory outcome. There is a reduction in the incidence of biliary complications with refinements in surgical techniques.
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