Literature DB >> 16504714

Assessment of early biliary complications after orthotopic liver transplantation and their relationship to the technique of biliary reconstruction.

A Alsharabi1, K Zieniewicz, W Patkowski, P Nyckowski, T Wroblewski, I Grzelak, B Michałowicz, R Paluszkiewicz, P Hevelke, P Remiszewski, B Cieślak, O Kornasiewicz, K Korba, A Skwarek, M Kotulski, U Ołdakowska, J Sanko-Resmer, L Paczek, M Krawczyk.   

Abstract

INTRODUCTION: Biliary complications are known as the weak point of liver transplantation. Their occurrence can be related to the practice of drainage of the biliary anastomosis, the routine use of which was abandoned in June 2004. The aim of the study was to assess the incidence and type of biliary complications following orthotopic liver transplantation in relation to the technique of biliary anastomosis.
MATERIAL AND METHODS: We compared the results of two groups of adult liver transplant recipients: group I, recent 50 transplantations with biliary drainage (25 women: 25 men of age range: 17 to 63 years), and group II, first 50 transplantations without drainage (19 women and 31 men of age range, 20 to 65 years). We examined the problem of biliary complications and their influence on the further management of the patients. In both groups the main indications for transplantation were various types of cirrhosis as well as cholestatic diseases. In the majority of cases (n = 86) an end-to-end common bile duct anastomosis was performed and in 14 cases, hepaticojejunal anastomosis.
RESULTS: In group I, biliary complications requiring surgical or endoscopic intervention occurred in 10 (20%) recipients. In one case, biliary complications resulted in the need for retransplantation. In group II, biliary complications occurred in only four (8%) patients, none of which caused organ loss.
CONCLUSION: Cessation of biliary anastomosis drainage has reduced the occurrence of early biliary complications following orthotopic liver transplantation.

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Year:  2006        PMID: 16504714     DOI: 10.1016/j.transproceed.2005.12.014

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  3 in total

1.  Post-transplant hepatic complications: Imaging findings.

Authors:  F M Drudi; E Pagliara; V Cantisani; F Arduini; U D'Ambrosio; G Alfano
Journal:  J Ultrasound       Date:  2007-04-16

Review 2.  A meta-analysis of complications following deceased donor liver transplant.

Authors:  Lisa M McElroy; Amna Daud; Ashley E Davis; Brittany Lapin; Talia Baker; Michael M Abecassis; Josh Levitsky; Jane L Holl; Daniela P Ladner
Journal:  Am J Surg       Date:  2014-07-18       Impact factor: 2.565

3.  Liver transplantation in Indian Armed Forces-initial experience.

Authors:  Anupam Saha; Cs Naidu; Gs Ramesh; Joy Chatterjee; Pankaj Puri; Bhaskar Nandi; Pradhi Nambiar; Renu Madan
Journal:  Med J Armed Forces India       Date:  2012-04-21
  3 in total

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