Literature DB >> 2459713

Two monoclonal rat antibodies with specificity for the beta-chain variable region V beta 6 of the murine T-cell receptor.

J Payne1, B T Huber, N A Cannon, R Schneider, M W Schilham, H Acha-Orbea, H R MacDonald, H Hengartner.   

Abstract

Two rat monoclonal antibodies (mAbs), 44-22-1 and 46-6B5, which recognize an alloreactive cytotoxic clone, 3F9, have been further tested on a panel of T hybridomas and cytotoxic T-cell clones for binding and functional activities. The mAbs recognized only those cells sharing the expression of the T-cell receptor beta-chain variable region gene V beta 6 with 3F9. All V beta 6+ cells were activated by these mAbs under cross-linking conditions and their antigen-specific activation was blocked by soluble mAb. Furthermore, depletion of 46-6B5+ normal lymph node T cells eliminated all cells expressing the epitope recognized by 44-22-1 and V beta 6 mRNA.

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Year:  1988        PMID： 2459713      PMCID： PMC282259          DOI： 10.1073/pnas.85.20.7695

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  20 in total

1.  Murine T-cell clones specific for chicken erythrocyte alloantigens.

Authors:  M A Giedlin; B M Longenecker; T R Mosmann
Journal:  Cell Immunol       Date:  1986-02       Impact factor: 4.868

2.  A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product.

Authors:  J W Kappler; T Wade; J White; E Kushnir; M Blackman; J Bill; N Roehm; P Marrack
Journal:  Cell       Date:  1987-04-24       Impact factor: 41.582

3.  Receptor diversity of insulin-specific T cell lines from C57BL (H-2b) mice.

Authors:  D G Spinella; T H Hansen; W D Walsh; M A Behlke; J P Tillinghast; H S Chou; P J Whiteley; J A Kapp; C W Pierce; E M Shevach
Journal:  J Immunol       Date:  1987-06-01       Impact factor: 5.422

4.  Identification of a monoclonal antibody specific for a murine T3 polypeptide.

Authors:  O Leo; M Foo; D H Sachs; L E Samelson; J A Bluestone
Journal:  Proc Natl Acad Sci U S A       Date:  1987-03       Impact factor: 11.205

5.  T cell tolerance by clonal elimination in the thymus.

Authors:  J W Kappler; N Roehm; P Marrack
Journal:  Cell       Date:  1987-04-24       Impact factor: 41.582

6.  Specific antigen-Ia activation of transfected human T cells expressing murine Ti alpha beta-human T3 receptor complexes.

Authors:  T Saito; A Weiss; J Miller; M A Norcross; R N Germain
Journal:  Nature       Date:  1987 Jan 8-14       Impact factor: 49.962

7.  Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody.

Authors:  J P Allison; B W McIntyre; D Bloch
Journal:  J Immunol       Date:  1982-11       Impact factor: 5.422

8.  Expression of a murine polyclonal T cell receptor marker correlates with the use of specific members of the V beta 8 gene segment subfamily.

Authors:  M A Behlke; T J Henkel; S J Anderson; N C Lan; L Hood; V L Braciale; T J Braciale; D Y Loh
Journal:  J Exp Med       Date:  1987-01-01       Impact factor: 14.307

9.  Contribution of antigen-presenting cell major histocompatibility complex gene products to the specificity of antigen-induced T cell activation.

Authors:  E Heber-Katz; R H Schwartz; L A Matis; C Hannum; T Fairwell; E Appella; D Hansburg
Journal:  J Exp Med       Date:  1982-04-01       Impact factor: 14.307

10.  T cell receptor variable gene usage in a specific cytotoxic T cell response. Primary structure of the antigen-MHC receptor of four hapten-specific cytotoxic T cell clones.

Authors:  A Iwamoto; P S Ohashi; H Pircher; C L Walker; E E Michalopoulos; F Rupp; H Hengartner; T W Mak
Journal:  J Exp Med       Date:  1987-03-01       Impact factor: 14.307
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  38 in total

1.  Immunohistowax processing, a new fixation and embedding method for light microscopy, which preserves antigen immunoreactivity and morphological structures: visualisation of dendritic cells in peripheral organs.

Authors:  B Pajak; T De Smedt; V Moulin; C De Trez; R Maldonado-López; G Vansanten; E Briend; J Urbain; O Leo; M Moser
Journal:  J Clin Pathol       Date:  2000-07       Impact factor: 3.411

2.  Thymus: a direct target tissue in graft-versus-host reaction after allogeneic bone marrow transplantation that results in abrogation of induction of self-tolerance.

Authors:  N Fukushi; H Arase; B Wang; K Ogasawara; T Gotohda; R A Good; K Onoé
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

3.  Intrathymic induction of neonatal tolerance to Mls-1a determinant: clonal deletion and clonal anergy by haematolymphoid cells.

Authors:  S Ideyama; M Hosono; S Imamura; M Tomana; Y Katsura
Journal:  Immunology       Date:  1991-10       Impact factor: 7.397

4.  Differential induction of interferon gamma gene expression after activation of CD4+ T cells by conventional antigen and Mls superantigen.

Authors:  R Patarca; F Y Wei; M V Iregui; H Cantor
Journal:  Proc Natl Acad Sci U S A       Date:  1991-04-01       Impact factor: 11.205

5.  Retrovirus-induced target cell activation in the early phases of infection: the mouse mammary tumor virus model.

Authors:  C Ardavin; F Luthi; M Andersson; L Scarpellino; P Martin; H Diggelmann; H Acha-Orbea
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103

6.  The stage of negative selection in tolerance induction in neonatal mice.

Authors:  T Ando; Y Yoshikai; G Matsuzaki; H Takimoto; K Nomoto
Journal:  Immunology       Date:  1991-12       Impact factor: 7.397

7.  Immunoregulatory activity of the T-cell receptor alpha chain demonstrated by retroviral gene transfer.

Authors:  D R Green; R Bissonnette; H G Zheng; T Onda; F Echeverri; R J Mogil; J K Steele; M Voralia; A Fotedar
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-01       Impact factor: 11.205

8.  Extrathymic origin of intestinal intraepithelial lymphocytes bearing T-cell antigen receptor gamma delta.

Authors:  A Bandeira; S Itohara; M Bonneville; O Burlen-Defranoux; T Mota-Santos; A Coutinho; S Tonegawa
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-01       Impact factor: 11.205

9.  A single retroviral gag precursor signal peptide recognized by FBL-3 tumor-specific cytotoxic T lymphocytes.

Authors:  T Kondo; H Uenishi; T Shimizu; T Hirama; M Iwashiro; K Kuribayashi; H Tamamura; N Fujii; R Fujisawa; M Miyazawa
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

10.  Systemic antibodies can inhibit mouse mammary tumor virus-driven superantigen response in mucosa-associated lymphoid tissues.

Authors:  D Velin; G Fotopoulos; J P Kraehenbuhl; H Acha-Orbea
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103
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