| Literature DB >> 2950524 |
O Leo, M Foo, D H Sachs, L E Samelson, J A Bluestone.
Abstract
A monoclonal antibody (145-2C11) specific for the murine T3 complex was derived by immunizing Armenian hamsters with a murine cytolytic T-cell clone. The antibody is specific for a 25-kDa protein component (T3-epsilon) of the antigen-specific T-cell receptor. It reacts with all mature T cells and can both activate and inhibit T-cell function. These results identify T3-epsilon as a cell surface protein involved in the transduction of activation signals.Entities:
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Year: 1987 PMID: 2950524 PMCID: PMC304432 DOI: 10.1073/pnas.84.5.1374
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205