Literature DB >> 3027582

Specific antigen-Ia activation of transfected human T cells expressing murine Ti alpha beta-human T3 receptor complexes.

T Saito, A Weiss, J Miller, M A Norcross, R N Germain.   

Abstract

The genes encoding the alpha and beta chains of the T-cell receptor (Ti) of an antigen-specific, Ia-restricted murine T-cell hybridoma were introduced into T3-positive or T3-negative human T cells. The resultant transfectants express either mouse-human or mouse-mouse Ti alpha beta molecules functionally associated with the human T3 complex. Only the complete murine Ti alpha beta dimer mediates specific functional corecognition of the appropriate antigen-Ia pair.

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Year:  1987        PMID： 3027582     DOI： 10.1038/325125a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  63 in total

1.  The KDEL receptor mediates a retrieval mechanism that contributes to quality control at the endoplasmic reticulum.

Authors:  K Yamamoto; R Fujii; Y Toyofuku; T Saito; H Koseki; V W Hsu; T Aoe
Journal:  EMBO J       Date:  2001-06-15       Impact factor: 11.598

Review 2.  Structure and function of the T cell antigen receptor.

Authors:  A Weiss
Journal:  J Clin Invest       Date:  1990-10       Impact factor: 14.808

3.  Antigen/major histocompatibility complex-specific activation of murine T cells transfected with functionally rearranged T-cell receptor genes.

Authors:  C L Kuo; L Hood
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

4.  T cell receptor phenotypes in autoimmune thyroid disease.

Authors:  W P Teng; S B Cohen; D N Posnett; A P Weetman
Journal:  J Endocrinol Invest       Date:  1990-04       Impact factor: 4.256

5.  Highly conserved T-cell receptor junctional regions. Evidence for selection at the protein and the DNA level.

Authors:  S B Sorger; S M Hedrick
Journal:  Immunogenetics       Date:  1990       Impact factor: 2.846

6.  An increase in number of T-cell receptor gamma/delta-bearing T cells in athymic nude mice treated with complete Freund's adjuvants.

Authors:  Y Yoshikai; G Matsuzaki; T Inoue; K Nomoto
Journal:  Immunology       Date:  1990-05       Impact factor: 7.397

7.  Structural mutations in the constant region of the T-cell antigen receptor (TCR)beta chain and their effect on TCR alpha and beta chain interaction.

Authors:  Z G Li; W P Wu; N Manolios
Journal:  Immunology       Date:  1996-08       Impact factor: 7.397

8.  CD4-Ia interactions can occur in the absence of T-cell receptor/antigen-Ia recognition.

Authors:  F Andris; O Leo; M Van Mechelen; J Urbain; M Slaoui
Journal:  Immunology       Date:  1989-09       Impact factor: 7.397

9.  T-cell receptor delta-chain diversity in peripheral lymphocytes.

Authors:  M J Lacy; L K McNeil; M E Roth; D M Kranz
Journal:  Proc Natl Acad Sci U S A       Date:  1989-02       Impact factor: 11.205

10.  Expression of T-cell receptor alpha-chain genes in transgenic mice.

Authors:  L J Berg; B Fazekas de St Groth; F Ivars; C C Goodnow; S Gilfillan; H J Garchon; M M Davis
Journal:  Mol Cell Biol       Date:  1988-12       Impact factor: 4.272
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