Literature DB >> 24525205

Current progress of aptamer-based molecular imaging.

Andrew Z Wang1, Omid C Farokhzad.   

Abstract

Aptamers, single-stranded oligonucleotides, are an important class of molecular targeting ligand. Since their discovery, aptamers have been rapidly translated into clinical practice. They have been approved as therapeutics and molecular diagnostics. Aptamers also possess several properties that make them uniquely suited to molecular imaging. This review aims to provide an overview of aptamers' advantages as targeting ligands and their application in molecular imaging.

Entities:  

Keywords:  aptamer; aptamers; molecular diagnostics; molecular imaging probes

Mesh：

Substances：

Year:  2014        PMID： 24525205      PMCID： PMC4110511          DOI： 10.2967/jnumed.113.126144

Source DB:  PubMed          Journal:  J Nucl Med        ISSN： 0161-5505            Impact factor:   10.057


  20 in total

Review 1.  Molecular imaging with nucleic acid aptamers.

Authors:  H Hong; S Goel; Y Zhang; W Cai
Journal:  Curr Med Chem       Date:  2011       Impact factor: 4.530

Review 2.  Nucleic acid aptamers: clinical applications and promising new horizons.

Authors:  X Ni; M Castanares; A Mukherjee; S E Lupold
Journal:  Curr Med Chem       Date:  2011       Impact factor: 4.530

3.  Aptamer-conjugated nanobubbles for targeted ultrasound molecular imaging.

Authors:  Chung-Hsin Wang; Yu-Fen Huang; Chih-Kuang Yeh
Journal:  Langmuir       Date:  2011-05-09       Impact factor: 3.882

4.  Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration.

Authors:  Hui Shi; Xiaoxiao He; Kemin Wang; Xu Wu; Xiaosheng Ye; Qiuping Guo; Weihong Tan; Zhihe Qing; Xiaohai Yang; Bing Zhou
Journal:  Proc Natl Acad Sci U S A       Date:  2011-02-22       Impact factor: 11.205

5.  A drug-loaded aptamer-gold nanoparticle bioconjugate for combined CT imaging and therapy of prostate cancer.

Authors:  Dongkyu Kim; Yong Yeon Jeong; Sangyong Jon
Journal:  ACS Nano       Date:  2010-07-27       Impact factor: 15.881

6.  A nucleolin-targeted multimodal nanoparticle imaging probe for tracking cancer cells using an aptamer.

Authors:  Do Won Hwang; Hae Young Ko; Jung Hwan Lee; Hyungu Kang; Sung Ho Ryu; In Chan Song; Dong Soo Lee; Soonhag Kim
Journal:  J Nucl Med       Date:  2009-12-15       Impact factor: 10.057

Review 7.  Molecular imaging of metastatic potential.

Authors:  Paul T Winnard; Arvind P Pathak; Surajit Dhara; Steven Y Cho; Venu Raman; Martin G Pomper
Journal:  J Nucl Med       Date:  2008-06       Impact factor: 10.057

8.  Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy.

Authors:  Andrew Z Wang; Vaishali Bagalkot; Christophoros C Vasilliou; Frank Gu; Frank Alexis; Liangfang Zhang; Mariam Shaikh; Kai Yuet; Michael J Cima; Robert Langer; Philip W Kantoff; Neil H Bander; Sangyong Jon; Omid C Farokhzad
Journal:  ChemMedChem       Date:  2008-09       Impact factor: 3.466

9.  From SOMAmer-based biomarker discovery to diagnostic and clinical applications: a SOMAmer-based, streamlined multiplex proteomic assay.

Authors:  Stephan Kraemer; Jonathan D Vaught; Christopher Bock; Larry Gold; Evaldas Katilius; Tracy R Keeney; Nancy Kim; Nicholas A Saccomano; Sheri K Wilcox; Dom Zichi; Glenn M Sanders
Journal:  PLoS One       Date:  2011-10-17       Impact factor: 3.240

10.  Anti-MUC1 aptamers: radiolabelling with (99m)Tc and biodistribution in MCF-7 tumour-bearing mice.

Authors:  Chiara Da Pieve; Alan C Perkins; Sotiris Missailidis
Journal:  Nucl Med Biol       Date:  2009-08       Impact factor: 2.408
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  25 in total

1.  Quick chip assay using locked nucleic acid modified epithelial cell adhesion molecule and nucleolin aptamers for the capture of circulating tumor cells.

Authors:  Nihal G Maremanda; Kislay Roy; Rupinder K Kanwar; Vidyarani Shyamsundar; Vijayalakshmi Ramshankar; Arvind Krishnamurthy; Subramanian Krishnakumar; Jagat R Kanwar
Journal:  Biomicrofluidics       Date:  2015-09-29       Impact factor: 2.800

2.  PET imaging of EGFR expression using an 18F-labeled RNA aptamer.

Authors:  Siyuan Cheng; Orit Jacobson; Guizhi Zhu; Zhen Chen; Steve H Liang; Rui Tian; Zhen Yang; Gang Niu; Xiaohua Zhu; Xiaoyuan Chen
Journal:  Eur J Nucl Med Mol Imaging       Date:  2018-08-01       Impact factor: 9.236

Review 3.  Trends in the Design and Development of Specific Aptamers Against Peptides and Proteins.

Authors:  Maryam Tabarzad; Marzieh Jafari
Journal:  Protein J       Date:  2016-04       Impact factor: 2.371

4.  Influence of 5-N-carboxamide modifications on the thermodynamic stability of oligonucleotides.

Authors:  Steven K Wolk; Richard K Shoemaker; Wes S Mayfield; Andrew L Mestdagh; Nebojsa Janjic
Journal:  Nucleic Acids Res       Date:  2015-10-04       Impact factor: 16.971

Review 5.  Aptamers: novel diagnostic and therapeutic tools for diabetes mellitus and metabolic diseases.

Authors:  Jingping Hu; Mao Ye; Zhiguang Zhou
Journal:  J Mol Med (Berl)       Date:  2016-11-15       Impact factor: 4.599

Review 6.  Peptide aptamers: development and applications.

Authors:  Sergey Reverdatto; David S Burz; Alexander Shekhtman
Journal:  Curr Top Med Chem       Date:  2015       Impact factor: 3.295

Review 7.  Aptamer-based targeted therapy.

Authors:  Guizhi Zhu; Xiaoyuan Chen
Journal:  Adv Drug Deliv Rev       Date:  2018-08-17       Impact factor: 15.470

Review 8.  Principles in the design of ligand-targeted cancer therapeutics and imaging agents.

Authors:  Madduri Srinivasarao; Chris V Galliford; Philip S Low
Journal:  Nat Rev Drug Discov       Date:  2015-02-20       Impact factor: 84.694

Review 9.  New radiotracers for imaging of vascular targets in angiogenesis-related diseases.

Authors:  Hao Hong; Feng Chen; Yin Zhang; Weibo Cai
Journal:  Adv Drug Deliv Rev       Date:  2014-07-30       Impact factor: 15.470

10.  Application of aptamers in diagnostics, drug-delivery and imaging.

Authors:  Chetan Chandola; Sheetal Kalme; Marco G Casteleijn; Arto Urtti; Muniasamy Neerathilingam
Journal:  J Biosci       Date:  2016-09       Impact factor: 2.795
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