Peng Wang1, Orhan Unal. 1. Medical Physics, University of Wisconsin - Madison, Wisconsin, USA.
Abstract
PURPOSE: To develop and evaluate a real-time proton resonant frequency (PRF) based MR thermometry method with a novel motion compensation technique, using linear phase model and active tracking coils. MATERIALS AND METHODS: A 6F catheter with multiple tracking coils and radiofrequency (RF) ablation tip was built for ex vivo experiments using excised bovine liver on a 1.5 Tesla scanner. A real-time MR acquisition scheme with interleaved active catheter tracking and multislice imaging was implemented. To evaluate the proposed method, in-plane periodic linear motion and through-plane irregular motion were induced by the rocker capability of the scanner and hand, respectively. Real-time temperature maps of the tissue undergoing a 2-min RF ablation cycle were obtained and used to compare the performance of the proposed method with that of the multi-baseline method. RESULTS: The temporal window achieved per acquisition of one slice and catheter tracking is ∼380 ms. The standard deviations of tracking errors are less than 1 mm for both irregular and periodic motions in x-y plane. The measurements at the heated and unheated regions demonstrate that the proposed thermometry method perform equally well for both in-plane and through-plane motion while maintaining a similar accuracy (σ = 1.10 versus 1.04°C) compared with the conventional multi-baseline method. CONCLUSION: The new MR thermometry method using catheter-based tracking coils and linear phase model for motion compensation and phase correction is promising and may offer reliable MR thermometry for real-time MRI-guided thermal therapies.
PURPOSE: To develop and evaluate a real-time proton resonant frequency (PRF) based MR thermometry method with a novel motion compensation technique, using linear phase model and active tracking coils. MATERIALS AND METHODS: A 6F catheter with multiple tracking coils and radiofrequency (RF) ablation tip was built for ex vivo experiments using excised bovine liver on a 1.5 Tesla scanner. A real-time MR acquisition scheme with interleaved active catheter tracking and multislice imaging was implemented. To evaluate the proposed method, in-plane periodic linear motion and through-plane irregular motion were induced by the rocker capability of the scanner and hand, respectively. Real-time temperature maps of the tissue undergoing a 2-min RF ablation cycle were obtained and used to compare the performance of the proposed method with that of the multi-baseline method. RESULTS: The temporal window achieved per acquisition of one slice and catheter tracking is ∼380 ms. The standard deviations of tracking errors are less than 1 mm for both irregular and periodic motions in x-y plane. The measurements at the heated and unheated regions demonstrate that the proposed thermometry method perform equally well for both in-plane and through-plane motion while maintaining a similar accuracy (σ = 1.10 versus 1.04°C) compared with the conventional multi-baseline method. CONCLUSION: The new MR thermometry method using catheter-based tracking coils and linear phase model for motion compensation and phase correction is promising and may offer reliable MR thermometry for real-time MRI-guided thermal therapies.
Authors: William A Grissom; Viola Rieke; Andrew B Holbrook; Yoav Medan; Michael Lustig; Juan Santos; Michael V McConnell; Kim Butts Pauly Journal: Med Phys Date: 2010-09 Impact factor: 4.071
Authors: Sophie C Rier; Suzan Vreemann; Wouter H Nijhof; Vincent J H M van Driel; Ivo A C van der Bilt Journal: Ther Adv Cardiovasc Dis Date: 2022 Jan-Dec