Literature DB >> 24416555

Volumetric modulated arc therapy for prostate cancer patients with hip prosthesis.

Ramachandran Prabhakar1, Milind Kumar2, Suja Cheruliyil2, Silpa Jayakumar2, Satheesan Balasubramanian2, Jim Cramb1.   

Abstract

AIM: To study the use of RapidArc techniques in the treatment of prostate cancer patients with hip prosthesis.
BACKGROUND: An important aspect of treatment planning is to achieve dose homogeneity inside the planning target volume (PTV). Especially for those patients presenting with hip prosthesis, it becomes a challenging task to achieve dose uniformity inside the PTV.
MATERIALS AND METHODS: Five prostate patients presenting with hip prosthesis who had undergone radical radiotherapy were selected for this study. Depending on the composition of prosthesis, a predefined set of Hounsfield values were assigned to each study set. RapidArc plans were generated on an Eclipse treatment planning system. Two arcs that include clockwise and counter-clockwise arcs were used in all these cases. To avoid beams passing through the prosthesis, a simple structure was defined around it with 1 cm margin and a strict dose constraint applied to the block during VMAT optimization.
RESULTS: The mean D2/D98 ratio of PTV for all the patients was 1.06 ± 0.01. The mean percentage rectum volume receiving 50 Gy, 60 Gy, 70 Gy and 75 Gy for all the patients were 33.1 ± 5.9, 21.7 ± 5.5, 13.8 ± 4.4 and 9.5 ± 3.0, respectively.
CONCLUSIONS: This study shows that using a double arc RapidArc technique is a simple and effective treatment method of treating prostate cancer in patients presenting with a hip prosthesis. The definition of a beam avoidance structure encompassing the prosthesis and applying strict dose constraints to it reduces the beam contribution to the prosthesis.

Entities:  

Keywords:  Prostate cancer; Prosthesis; Radiotherapy; Treatment planning; VMAT

Year:  2013        PMID: 24416555      PMCID: PMC3863326          DOI: 10.1016/j.rpor.2013.03.006

Source DB:  PubMed          Journal:  Rep Pract Oncol Radiother        ISSN: 1507-1367


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