Literature DB >> 24416545

Measurement verification of dose distributions in pulsed-dose rate brachytherapy in breast cancer.

Patrycja Mantaj1, Grzegorz Zwierzchowski2.   

Abstract

AIM: The aim of the study was to verify the dose distribution optimisation method in pulsed brachytherapy.
BACKGROUND: The pulsed-dose rate brachytherapy is a very important method of breast tumour treatment using a standard brachytheraphy equipment. The appropriate dose distribution round an implant is an important issue in treatment planning. Advanced computer systems of treatment planning are equipped with algorithms optimising dose distribution.
MATERIALS AND METHODS: The wax-paraffin phantom was constructed and seven applicators were placed within it. Two treatment plans (non-optimised, optimised) were prepared. The reference points were located at a distance of 5 mm from the applicators' axis. Thermoluminescent detectors were placed in the phantom at suitable 35 chosen reference points.
RESULTS: The dosimetry verification was carried out in 35 reference points for the plans before and after optimisation. Percentage difference for the plan without optimisation ranged from -8.5% to 1.4% and after optimisation from -8.3% to 0.01%. In 16 reference points, the calculated percentage difference was negative (from -8.5% to 1.3% for the plan without optimisation and from -8.3% to 0.8% for the optimised plan). In the remaining 19 points percentage difference was from 9.1% to 1.4% for the plan without optimisation and from 7.5% to 0.01% for the optimised plan. No statistically significant differences were found between calculated doses and doses measured at reference points in both dose distribution non-optimised treatment plans and optimised treatment plans.
CONCLUSIONS: No statistically significant differences were found in dose values at reference points between doses calculated by the treatment planning system and those measured by TLDs. This proves the consistency between the measurements and the calculations.

Entities:  

Keywords:  Gafchromic EBT dosimetry; Implant; Pulse brachytherapy; Thermoluminescent detectors

Year:  2013        PMID: 24416545      PMCID: PMC3863283          DOI: 10.1016/j.rpor.2013.03.001

Source DB:  PubMed          Journal:  Rep Pract Oncol Radiother        ISSN: 1507-1367


  12 in total

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Authors:  J F Dempsey; D A Low; A S Kirov; J F Williamson
Journal:  Med Phys       Date:  1999-08       Impact factor: 4.071

2.  In-phantom response of LiF TLD-100 for dosimetry of 192Ir HDR source.

Authors:  A S Pradhan; U Quast
Journal:  Med Phys       Date:  2000-05       Impact factor: 4.071

3.  Radiochromic film dosimetry in water phantoms.

Authors:  M J Butson; T Cheung; P K Yu
Journal:  Phys Med Biol       Date:  2001-01       Impact factor: 3.609

4.  Use of multiple layers of Gafchromic film to increase sensitivity.

Authors:  T Cheung; M J Butso; P K Yu
Journal:  Phys Med Biol       Date:  2001-10       Impact factor: 3.609

5.  High sensitivity radiochromic film dose comparisons.

Authors:  Martin J Butson; Peter K N Yu; Tsang Cheung; Peter Metcalfe
Journal:  Phys Med Biol       Date:  2002-11-21       Impact factor: 3.609

6.  Polarization effects on a high-sensitivity radiochromic film.

Authors:  Martin J Butson; Peter K N Yu; Tsang Cheung; Dean Inwood
Journal:  Phys Med Biol       Date:  2003-08-07       Impact factor: 3.609

7.  Radiochromic film measurement of anisotropy function for high-dose-rate Ir-192 brachytherapy source.

Authors:  S D Sharma; C Bianchi; L Conte; R Novario; B C Bhatt
Journal:  Phys Med Biol       Date:  2004-09-07       Impact factor: 3.609

8.  GafChromic MD-55: investigated as a precision dosimeter.

Authors:  N V Klassen; L van der Zwan; J Cygler
Journal:  Med Phys       Date:  1997-12       Impact factor: 4.071

9.  Dosimetric characteristics of an improved radiochromic film.

Authors:  A S Meigooni; M F Sanders; G S Ibbott; S R Szeglin
Journal:  Med Phys       Date:  1996-11       Impact factor: 4.071

10.  Comparison of dose response of radiochromic film measured with He-Ne laser, broadband, and filtered light densitometers.

Authors:  L E Reinstein; G R Gluckman
Journal:  Med Phys       Date:  1997-09       Impact factor: 4.071

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