| Literature DB >> 24415481 |
Sonja Siljak-Yakovlev1, Fatima Pustahija, Vedrana Vicic, Odile Robin.
Abstract
Fluorochrome banding (chromomycin, Hoechst, and DAPI) and fluorescence in situ hybridization (FISH) are excellent molecular cytogenetic tools providing various possibilities in the study of chromosomal evolution and genome organization. The constitutive heterochromatin and rRNA genes are the most widely used FISH markers. The rDNA is organized into two distinct gene families (18S-5.8S-26S and 5S) whose number and location vary within the complex of closely related species. Therefore, they are widely used as chromosomal landmarks to provide valuable evidence concerning genome evolution at chromosomal levels.Entities:
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Year: 2014 PMID: 24415481 DOI: 10.1007/978-1-62703-767-9_15
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745