Literature DB >> 24393198

The 2-year cost-effectiveness of 3 options to treat lumbar spinal stenosis patients.

Belinda L Udeh1, Shrif Costandi, Jarrod E Dalton, Raktim Ghosh, Hani Yousef, Nagy Mekhail.   

Abstract

Lumbar spinal stenosis (LSS) may result from degenerative changes of the spine, which lead to neural ischemia, neurogenic claudication, and a significant decrease in quality of life. Treatments for LSS range from conservative management including epidural steroid injections (ESI) to laminectomy surgery. Treatments vary greatly in cost and success. ESI is the least costly treatment may be successful for early stages of LSS but often must be repeated frequently. Laminectomy surgery is more costly and has higher complication rates. Minimally invasive lumbar decompression (mild(®) ) is an alternative. Using a decision-analytic model from the Medicare perspective, a cost-effectiveness analysis was performed comparing mild(®) to ESI or laminectomy surgery. The analysis population included patients with LSS who have moderate to severe symptoms and have failed conservative therapy. Costs included initial procedure, complications, and repeat/revision or alternate procedure after failure. Effects measured as change in quality-adjusted life years (QALY) from preprocedure to 2 years postprocedure. Incremental cost-effectiveness ratios were determined, and sensitivity analysis conducted. The mild(®) strategy appears to be the most cost-effective ($43,760/QALY), with ESI the next best alternative at an additional $37,758/QALY. Laminectomy surgery was the least cost-effective ($125,985/QALY).
© 2014 World Institute of Pain.

Entities:  

Keywords:  cost-effectiveness; economics; lower back pain; lumbar spinal stenosis; mild procedure; quality-adjusted life years; surgical procedures

Mesh:

Substances:

Year:  2014        PMID: 24393198      PMCID: PMC4786075          DOI: 10.1111/papr.12160

Source DB:  PubMed          Journal:  Pain Pract        ISSN: 1530-7085            Impact factor:   3.183


  26 in total

1.  Cost-effectiveness of fusion with and without instrumentation for patients with degenerative spondylolisthesis and spinal stenosis.

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Journal:  Spine (Phila Pa 1976)       Date:  2000-05-01       Impact factor: 3.468

Review 2.  Thinking outside the box: recent advances in the analysis and presentation of uncertainty in cost-effectiveness studies.

Authors:  Andrew H Briggs; Bernie J O'Brien; Gordon Blackhouse
Journal:  Annu Rev Public Health       Date:  2001-10-25       Impact factor: 21.981

3.  A double-blind, randomized, prospective study of epidural steroid injection vs. the mild® procedure in patients with symptomatic lumbar spinal stenosis.

Authors:  Lora L Brown
Journal:  Pain Pract       Date:  2012-01-25       Impact factor: 3.183

Review 4.  Recommendations of the Panel on Cost-effectiveness in Health and Medicine.

Authors:  M C Weinstein; J E Siegel; M R Gold; M S Kamlet; L B Russell
Journal:  JAMA       Date:  1996-10-16       Impact factor: 56.272

5.  A prospective evaluation of complications of 10,000 fluoroscopically directed epidural injections.

Authors:  Laxmaiah Manchikanti; Yogesh Malla; Bradley W Wargo; Kimberly A Cash; Vidyasagar Pampati; Bert Fellows
Journal:  Pain Physician       Date:  2012 Mar-Apr       Impact factor: 4.965

6.  Cost-effectiveness of multilevel hemilaminectomy for lumbar stenosis-associated radiculopathy.

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Journal:  Spine J       Date:  2011-06-08       Impact factor: 4.166

7.  Epidural steroid injections are associated with less improvement in patients with lumbar spinal stenosis: a subgroup analysis of the Spine Patient Outcomes Research Trial.

Authors:  Kris Radcliff; Christopher Kepler; Alan Hilibrand; Jeffrey Rihn; Wenyan Zhao; Jon Lurie; Tor Tosteson; Alexander Vaccaro; Todd Albert; James Weinstein
Journal:  Spine (Phila Pa 1976)       Date:  2013-02-15       Impact factor: 3.468

8.  Trends, major medical complications, and charges associated with surgery for lumbar spinal stenosis in older adults.

Authors:  Richard A Deyo; Sohail K Mirza; Brook I Martin; William Kreuter; David C Goodman; Jeffrey G Jarvik
Journal:  JAMA       Date:  2010-04-07       Impact factor: 56.272

9.  Surgical treatment of spinal stenosis with and without degenerative spondylolisthesis: cost-effectiveness after 2 years.

Authors:  Anna N A Tosteson; Jon D Lurie; Tor D Tosteson; Jonathan S Skinner; Harry Herkowitz; Todd Albert; Scott D Boden; Keith Bridwell; Michael Longley; Gunnar B Andersson; Emily A Blood; Margaret R Grove; James N Weinstein
Journal:  Ann Intern Med       Date:  2008-12-16       Impact factor: 25.391

10.  Predicting SF-6D utility scores from the Oswestry disability index and numeric rating scales for back and leg pain.

Authors:  Leah Y Carreon; Steven D Glassman; Christine M McDonough; Raja Rampersaud; Sigurd Berven; Michael Shainline
Journal:  Spine (Phila Pa 1976)       Date:  2009-09-01       Impact factor: 3.468

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1.  Cost-effectiveness of conservative versus surgical treatment strategies of lumbar spinal stenosis in the Swiss setting: analysis of the prospective multicenter Lumbar Stenosis Outcome Study (LSOS).

Authors:  A Aichmair; J M Burgstaller; M Schwenkglenks; J Steurer; F Porchet; F Brunner; M Farshad
Journal:  Eur Spine J       Date:  2016-12-31       Impact factor: 3.134

2.  Complications associated with L4-5 anterior retroperitoneal trans-psoas interbody fusion: a single institution series.

Authors:  Saeed S Sadrameli; Vitaliy Davidov; Meng Huang; Jonathan J Lee; Srivathsan Ramesh; Jaime R Guerrero; Marcus S Wong; Zain Boghani; Adriana Ordonez; Sean M Barber; Todd W Trask; Andrew C Roeser; Paul J Holman
Journal:  J Spine Surg       Date:  2020-09

3.  Systematic Review of Cost-Effectiveness Analyses Comparing Open and Minimally Invasive Lumbar Spinal Surgery.

Authors:  Kelechi Eseonu; Uche Oduoza; Mohamed Monem; Mohamed Tahir
Journal:  Int J Spine Surg       Date:  2022-07-14

Review 4.  Spinal Cord Stimulation, MILD Procedure, and Regenerative Medicine, Novel Interventional Nonopioid Therapies in Chronic Pain.

Authors:  Ken P Ehrhardt; Susan M Mothersele; Andrew J Brunk; Jeremy B Green; Mark R Jones; Craig B Billeaud; Alan David Kaye
Journal:  Curr Pain Headache Rep       Date:  2018-03-19

5.  The Influence of Exercise on Perceived Pain and Disability in Patients With Lumbar Spinal Stenosis: A Systematic Review of Randomized Controlled Trials.

Authors:  Jarrett Slater; Morey J Kolber; Kristen C Schellhase; Chetan K Patel; Carey E Rothschild; Xinliang Liu; William J Hanney
Journal:  Am J Lifestyle Med       Date:  2015-02-16

6.  The durability of minimally invasive lumbar decompression procedure in patients with symptomatic lumbar spinal stenosis: Long-term follow-up.

Authors:  Nagy Mekhail; Shrif Costandi; George Nageeb; Catherine Ekladios; Ogena Saied
Journal:  Pain Pract       Date:  2021-05-13       Impact factor: 3.079

7.  The Impact of Age on the Outcomes of Minimally Invasive Lumbar Decompression for Lumbar Spinal Stenosis.

Authors:  Nagy A Mekhail; Shrif J Costandi; Sherif Armanyous; Ricardo Vallejo; Lawrence R Poree; Lora L Brown; Stanley Golovac; Timothy R Deer
Journal:  Med Devices (Auckl)       Date:  2020-06-04

8.  Sex-Dependent Differences in Symptom-Related Disability Due to Lumbar Spinal Stenosis.

Authors:  Raffael Peteler; Paul Schmitz; Martin Loher; Petra Jansen; Joachim Grifka; Achim Benditz
Journal:  J Pain Res       Date:  2021-03-16       Impact factor: 3.133

9.  Preoperative Cognitive Impairment as a Predictor of Postoperative Outcomes in Elderly Patients Undergoing Spinal Surgery for Degenerative Spinal Disease.

Authors:  Hyung Cheol Kim; Seong Bae An; Hyeongseok Jeon; Tae Woo Kim; Jae Keun Oh; Dong Ah Shin; Seong Yi; Keung Nyun Kim; Phil Hyu Lee; Suk Yun Kang; Yoon Ha
Journal:  J Clin Med       Date:  2021-03-30       Impact factor: 4.241

10.  Effects of calcitonin addition on epidural injection in patients with degenerative spinal canal stenosis: a randomized double blind clinical trial.

Authors:  Poupak Rahimzadeh; Seyed Mani Mahdavi; Kamran Mahmoudi; Hassan Ghandhari; Ali Babashahi; Parvaneh Zandi; Seyed Hamid Reza Faiz
Journal:  Turk J Anaesthesiol Reanim       Date:  2021-12
  10 in total

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