| Literature DB >> 24355094 |
H T Lynch1, C Snyder, M Stacey, B Olson, S K Peterson, S Buxbaum, T Shaw, P M Lynch.
Abstract
When a cancer predisposing germline mutation is detected in an index case, the presence of the underlying syndrome is confirmed and the potential for predictive testing of at-risk relatives is established. However, the reporting of a positive family history does not routinely lead to communication of information about risk to close, much less distant relatives. This review summarizes information technology utilized to address penetration or 'reach' of knowledge of risk within extended families, including the use of telephone and video counseling to reach distant patients, and anticipate novel internet-based processes for communication between investigators and relatives.Entities:
Keywords: Lynch syndrome; colorectal cancer; familial cancer; genetic counseling; genetic testing; hereditary cancer; hereditary non-polyposis colorectal cancer; information technology
Mesh:
Year: 2013 PMID: 24355094 PMCID: PMC4371849 DOI: 10.1111/cge.12317
Source DB: PubMed Journal: Clin Genet ISSN: 0009-9163 Impact factor: 4.438