Literature DB >> 24287638

Osteolysis in cemented total hip arthroplasty involving the OptiPlug cement restrictor: more than an incident?

N M A I Hanssen1, M G M Schotanus, A D Verburg.   

Abstract

The case report of a severe osteolytic reaction surrounding the OptiPlug cement restrictor in a 74-year-old male patient initiated a retrospective case series and closer investigation into the OptiPlug and its active compound, PolyActive. Not only did we find several cases of severe osteolysis in our own study population of 284 patients, several articles have lately described potential harmful side effects of the PolyActive material in humans. Although none of the articles have been based on large databases, we cannot guarantee the safety of this product. More research would help in our understanding of this phenomenon. Until then, we cannot recommend the use of the OptiPlug cement restrictor.

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Year:  2013        PMID： 24287638     DOI： 10.1007/s00590-013-1366-z

Source DB:  PubMed          Journal:  Eur J Orthop Surg Traumatol        ISSN： 1633-8065


  24 in total

1.  In vitro performance of intramedullary cement restrictors in total hip arthroplasty.

Authors:  C Heisel; T Norman; R Rupp; M Pritsch; V Ewerbeck; S J Breusch
Journal:  J Biomech       Date:  2003-06       Impact factor: 2.712

2.  Poor results with the Shuttle Stop: resorbable versus nonresorbable intramedullar cement restrictor in a prospective and randomized study with a 2-year follow-up.

Authors:  Knud Gade Freund; Niels Herold; Niels D Røck; Per Riegels-Nielsen
Journal:  Acta Orthop Scand       Date:  2003-02

3.  Periprosthetic femoral fracture due to biodegradable cement restrictor.

Authors:  Rohit Kumar Dhawan; David C Mangham; Niall M Graham
Journal:  J Arthroplasty       Date:  2012-04-20       Impact factor: 4.757

4.  Missing osteoconductive effect of a resorbable PEO/PBT copolymer in human bone defects: a clinically relevant pilot study with contrary results to previous animal studies.

Authors:  M Roessler; A Wilke; P Griss; H Kienapfel
Journal:  J Biomed Mater Res       Date:  2000

5.  Femoral canal occlusion in total hip replacement using a resorbable and flexible cement restrictor.

Authors:  S K Bulstra; R G Geesink; D Bakker; T H Bulstra; S J Bouwmeester; A J van der Linden
Journal:  J Bone Joint Surg Br       Date:  1996-11

6.  Interface reactions to PEO/PBT copolymers (Polyactive) after implantation in cortical bone.

Authors:  A M Radder; H Leenders; C A van Blitterswijk
Journal:  J Biomed Mater Res       Date:  1994-02

7.  Bone growth in biomimetic apatite coated porous Polyactive 1000PEGT70PBT30 implants.

Authors:  C Du; G J Meijer; C van de Valk; R E Haan; J M Bezemer; S C Hesseling; F Z Cui; K de Groot; P Layrolle
Journal:  Biomaterials       Date:  2002-12       Impact factor: 12.479

8.  Quantitative histological analysis of bony ingrowth within the biomaterial Polyactive implanted in different bone locations: an experimental study in rabbits.

Authors:  S J Bouwmeester; R Kuijer; M M Sollie-Drees; A J van der Linden; S K Bulstra
Journal:  J Mater Sci Mater Med       Date:  1998-04       Impact factor: 3.896

9.  PEOT/PBT based scaffolds with low mechanical properties improve cartilage repair tissue formation in osteochondral defects.

Authors:  Edwin J P Jansen; Jeroen Pieper; Marion J J Gijbels; Nick A Guldemond; Jens Riesle; Lodewijk W Van Rhijn; Sjoerd K Bulstra; Roel Kuijer
Journal:  J Biomed Mater Res A       Date:  2009-05       Impact factor: 4.396

10.  A comparison of distal canal restrictors in primary cemented femoral hip arthroplasty.

Authors:  Eric L Smith; Kurt P Wohlrab; Elizabeth G Matzkin; Bertram C Providence
Journal:  Orthopedics       Date:  2004-08       Impact factor: 1.390
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  1 in total

1.  Osteolytic changes around biodegradable cement restrictors in hip surgery.

Authors:  Matthias Erschbamer; Vilijam Zdravkovic; Johannes Erhardt; Christian Öhlschlegel; Karl Grob
Journal:  Acta Orthop       Date:  2016-02-24       Impact factor: 3.717
  1 in total

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