Literature DB >> 24270443

Epigenetics, vitamin supplements and cellular reprogramming.

Martin F Pera1.   

Abstract

The simple addition of vitamin C to cell culture medium can induce extensive remodeling of the cellular epigenome and facilitates reprogramming of somatic cells to pluripotency. A new study shows that the activity of the enzyme TET1 can inhibit or enhance reprogramming efficiency, dependent on the presence or absence of vitamin C.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 24270443     DOI： 10.1038/ng.2834

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  11 in total

Review 1.  Genetic and epigenetic stability of human pluripotent stem cells.

Authors:  Riikka J Lund; Elisa Närvä; Riitta Lahesmaa
Journal:  Nat Rev Genet       Date:  2012-09-11       Impact factor: 53.242

2.  The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner.

Authors:  Tao Wang; Keshi Chen; Xiaoming Zeng; Jianguo Yang; Yun Wu; Xi Shi; Baoming Qin; Lingwen Zeng; Miguel Angel Esteban; Guangjin Pan; Duanqing Pei
Journal:  Cell Stem Cell       Date:  2011-11-17       Impact factor: 24.633

3.  Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.

Authors:  Hao Wu; Ana C D'Alessio; Shinsuke Ito; Kai Xia; Zhibin Wang; Kairong Cui; Keji Zhao; Yi Eve Sun; Yi Zhang
Journal:  Nature       Date:  2011-03-30       Impact factor: 49.962

Review 4.  Breathing-in epigenetic change with vitamin C.

Authors:  Asun Monfort; Anton Wutz
Journal:  EMBO Rep       Date:  2013-03-15       Impact factor: 8.807

5.  Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming.

Authors:  Yawei Gao; Jiayu Chen; Ke Li; Tong Wu; Bo Huang; Wenqiang Liu; Xiaochen Kou; Yu Zhang; Hua Huang; Yonghua Jiang; Chao Yao; Xiaolei Liu; Zhiwei Lu; Zijian Xu; Lan Kang; Jun Chen; Hailin Wang; Tao Cai; Shaorong Gao
Journal:  Cell Stem Cell       Date:  2013-03-14       Impact factor: 24.633

6.  Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.

Authors:  Meelad M Dawlaty; Achim Breiling; Thuc Le; Günter Raddatz; M Inmaculada Barrasa; Albert W Cheng; Qing Gao; Benjamin E Powell; Zhe Li; Mingjiang Xu; Kym F Faull; Frank Lyko; Rudolf Jaenisch
Journal:  Dev Cell       Date:  2013-01-24       Impact factor: 12.270

7.  Vitamin C modulates TET1 function during somatic cell reprogramming.

Authors:  Jiekai Chen; Lin Guo; Lei Zhang; Haoyu Wu; Jiaqi Yang; He Liu; Xiaoshan Wang; Xiao Hu; Tianpeng Gu; Zhiwei Zhou; Jing Liu; Jiadong Liu; Hongling Wu; Shi-Qing Mao; Kunlun Mo; Yingying Li; Keyu Lai; Jing Qi; Hongjie Yao; Guangjin Pan; Guo-Liang Xu; Duanqing Pei
Journal:  Nat Genet       Date:  2013-10-27       Impact factor: 38.330

Review 8.  Ten eleven translocation enzymes and 5-hydroxymethylation in mammalian development and cancer.

Authors:  Shannon R Morey Kinney; Sriharsa Pradhan
Journal:  Adv Exp Med Biol       Date:  2013       Impact factor: 2.622

9.  Vitamin C enhances the generation of mouse and human induced pluripotent stem cells.

Authors:  Miguel Angel Esteban; Tao Wang; Baoming Qin; Jiayin Yang; Dajiang Qin; Jinglei Cai; Wen Li; Zhihui Weng; Jiekai Chen; Su Ni; Keshi Chen; Yuan Li; Xiaopeng Liu; Jianyong Xu; Shiqiang Zhang; Feng Li; Wenzhi He; Krystyna Labuda; Yancheng Song; Anja Peterbauer; Susanne Wolbank; Heinz Redl; Mei Zhong; Daozhang Cai; Lingwen Zeng; Duanqing Pei
Journal:  Cell Stem Cell       Date:  2009-12-31       Impact factor: 24.633

10.  NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

Authors:  Yael Costa; Junjun Ding; Thorold W Theunissen; Francesco Faiola; Timothy A Hore; Pavel V Shliaha; Miguel Fidalgo; Arven Saunders; Moyra Lawrence; Sabine Dietmann; Satyabrata Das; Dana N Levasseur; Zhe Li; Mingjiang Xu; Wolf Reik; José C R Silva; Jianlong Wang
Journal:  Nature       Date:  2013-02-10       Impact factor: 49.962
View more
  4 in total

Review 1.  Micro but mighty-Micronutrients in the epigenetic regulation of adaptive immune responses.

Authors:  Heng-Yi Chen; Michael Hsu; Chan-Wang Jerry Lio
Journal:  Immunol Rev       Date:  2021-11-24       Impact factor: 12.988

2.  Sensing risk, fearing uncertainty: systems science approach to change.

Authors:  Ivo P Janecka
Journal:  Front Comput Neurosci       Date:  2014-03-31       Impact factor: 2.380

3.  Vitamin C alleviates aging defects in a stem cell model for Werner syndrome.

Authors:  Ying Li; Weizhou Zhang; Liang Chang; Yan Han; Liang Sun; Xiaojun Gong; Hong Tang; Zunpeng Liu; Huichao Deng; Yanxia Ye; Yu Wang; Jian Li; Jie Qiao; Jing Qu; Weiqi Zhang; Guang-Hui Liu
Journal:  Protein Cell       Date:  2016-06-06       Impact factor: 14.870

Review 4.  Who Rules the Cell? An Epi-Tale of Histone, DNA, RNA, and the Metabolic Deep State.

Authors:  Jeffrey Leung; Valérie Gaudin
Journal:  Front Plant Sci       Date:  2020-03-05       Impact factor: 5.753
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.