| Literature DB >> 2416779 |
Abstract
A near full-length cDNA encoding the human vitamin D-binding protein (hDBP) was isolated from a human liver mRNA expression library. Complete sequence analysis of this clone predicts the full-length amino acid sequence of the pre-hDBP. Comparison of the sequence of the hDBP mRNA and protein to existing protein and nucleic acid data banks demonstrates a strong and highly characteristic homology of the hDBP with human albumin (hALB) and human alpha-fetoprotein (hAFP). Based upon this structural comparison, we establish that DBP is a member of the ALB and AFP gene family.Entities:
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Year: 1985 PMID: 2416779 PMCID: PMC424397 DOI: 10.1172/JCI112256
Source DB: PubMed Journal: J Clin Invest ISSN: 0021-9738 Impact factor: 14.808