Literature DB >> 24120985

Sexual functioning and sex hormones in persons with extreme obesity and seeking surgical and nonsurgical weight loss.

David B Sarwer1, Jacqueline C Spitzer, Thomas A Wadden, Raymond C Rosen, James E Mitchell, Kathy Lancaster, Anita Courcoulas, William Gourash, Nicholas J Christian.   

Abstract

BACKGROUND: Many individuals with obesity are motivated to lose weight to improve weight-related co-morbidities or psychosocial functioning, including sexual functioning. Few studies have documented rates of sexual dysfunction in persons with obesity. This study investigated sexual functioning, sex hormones, and relevant psychosocial constructs in individuals with obesity who sought surgical and nonsurgical weight loss.
METHODS: One hundred forty-one bariatric surgery patients (median BMI [25th percentile, 75th percentile] 44.6 [41.4, 50.1]) and 109 individuals (BMI = 40.0 [38.0, 44.0]) who sought nonsurgical weight loss participated. Sexual functioning was assessed by the Female Sexual Function Index (FSFI) and the International Index of Erectile Function (IIEF). Hormones were assessed by blood assay. Quality of life, body image, depressive symptoms, and marital adjustment were assessed by validated questionnaires.
RESULTS: Fifty-one percent of women presenting for bariatric surgery reported a sexual dysfunction; 36% of men presenting for bariatric surgery reported erectile dysfunction (ED). This is in contrast to 41% of women who sought nonsurgical weight loss and reported a sexual dysfunction and 20% of men who sought nonsurgical weight loss and reported ED. These differences were not statistically significant. Sexual dysfunction was strongly associated with psychosocial distress in women; these relationships were less strong and less consistent among men. Sexual dysfunction was unrelated to sex hormones, except for sex hormone binding globulin (SHGB) in women.
CONCLUSION: Women and men who present for bariatric surgery, compared with individuals who sought nonsurgical weight loss, were not significantly more likely to experience a sexual dysfunction. There were few differences in reproductive hormones and psychosocial constructs between candidates for bariatric surgery and individuals interested in nonsurgical weight loss.
Copyright © 2013 American Society for Metabolic and Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Obesity; Quality of life; Sexual functioning

Mesh:

Substances:

Year:  2013        PMID: 24120985      PMCID: PMC3864660          DOI: 10.1016/j.soard.2013.07.003

Source DB:  PubMed          Journal:  Surg Obes Relat Dis        ISSN: 1550-7289            Impact factor:   4.734


  27 in total

1.  The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function.

Authors:  R Rosen; C Brown; J Heiman; S Leiblum; C Meston; R Shabsigh; D Ferguson; R D'Agostino
Journal:  J Sex Marital Ther       Date:  2000 Apr-Jun

2.  Sexual desire and the female sexual function index (FSFI): a sexual desire cutpoint for clinical interpretation of the FSFI in women with and without hypoactive sexual desire disorder.

Authors:  Eric P Gerstenberger; Raymond C Rosen; Jessica V Brewer; Cindy M Meston; Lori A Brotto; Markus Wiegel; Michael Sand
Journal:  J Sex Med       Date:  2010-09       Impact factor: 3.802

3.  Development of a brief measure to assess quality of life in obesity.

Authors:  R L Kolotkin; R D Crosby; K D Kosloski; G R Williams
Journal:  Obes Res       Date:  2001-02

Review 4.  A review of the relationships between extreme obesity, quality of life, and sexual function.

Authors:  David B Sarwer; Megan Lavery; Jacqueline C Spitzer
Journal:  Obes Surg       Date:  2012-04       Impact factor: 4.129

5.  Does hypertension and its pharmacotherapy affect the quality of sexual function in women?

Authors:  L E Duncan; C Lewis; P Jenkins; T A Pearson
Journal:  Am J Hypertens       Date:  2000-06       Impact factor: 2.689

Review 6.  Sexual functioning and obesity: a review.

Authors:  Ronette L Kolotkin; Christie Zunker; Truls Østbye
Journal:  Obesity (Silver Spring)       Date:  2012-04-23       Impact factor: 5.002

7.  Prevalence and degree of sexual dysfunction in a sample of women seeking bariatric surgery.

Authors:  Dale S Bond; Siva Vithiananthan; Tricia M Leahey; J Graham Thomas; Harry C Sax; Dieter Pohl; Beth A Ryder; G Dean Roye; Jeannine Giovanni; Rena R Wing
Journal:  Surg Obes Relat Dis       Date:  2009-07-24       Impact factor: 4.734

8.  Relationship of body mass index with demographic and clinical characteristics in the Longitudinal Assessment of Bariatric Surgery (LABS).

Authors:  Steven H Belle; William Chapman; Anita P Courcoulas; David R Flum; Michel Gagner; William B Inabnet; Wendy C King; James E Mitchell; Emma J Patterson; Richard Thirlby; Bruce M Wolfe; Susan Z Yanovski
Journal:  Surg Obes Relat Dis       Date:  2008-06-02       Impact factor: 4.734

9.  Erectile dysfunction in type 2 diabetic men: relationship to exercise fitness and cardiovascular risk factors in the Look AHEAD trial.

Authors:  Raymond C Rosen; Rena R Wing; Stephen Schneider; Thomas A Wadden; Gary D Foster; Delia Smith West; Abbas E Kitabchi; Frederick L Brancati; Barbara J Maschak-Carey; Judy L Bahnson; Cora E Lewis; Isaias N Gendrano Iii
Journal:  J Sex Med       Date:  2009-01-31       Impact factor: 3.802

10.  Relationship between sexual function and quality of life in obese persons seeking weight reduction.

Authors:  Reneé H Moore; David B Sarwer; Jeffrey A Lavenberg; Ilana B Lane; Joanna L Evans; Sheri Volger; Thomas A Wadden
Journal:  Obesity (Silver Spring)       Date:  2013-05-31       Impact factor: 5.002

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  19 in total

Review 1.  Change in Sexual Dysfunction Following Bariatric Surgery.

Authors:  Laura R Wingfield; Myutan Kulendran; Georgia Laws; Harvinder Chahal; Samantha Scholtz; Sanjay Purkayastha
Journal:  Obes Surg       Date:  2016-02       Impact factor: 4.129

2.  Changes in Dietary Intake and Eating Behavior in Adolescents After Bariatric Surgery: an Ancillary Study to the Teen-LABS Consortium.

Authors:  David B Sarwer; Rebecca J Dilks; Jacqueline C Spitzer; Robert I Berkowitz; Thomas A Wadden; Renee H Moore; Jesse L Chittams; Mary L Brandt; Mike K Chen; Anita P Courcoulas; Carroll M Harmon; Michael A Helmrath; Marc P Michalsky; Stavra A Xanthakos; Meg H Zeller; Todd M Jenkins; Thomas H Inge
Journal:  Obes Surg       Date:  2017-12       Impact factor: 4.129

3.  Sexual functioning of men and women with severe obesity before bariatric surgery.

Authors:  Kristine J Steffen; Wendy C King; Gretchen E White; Leslee L Subak; James E Mitchell; Anita P Courcoulas; David R Flum; Gladys Strain; David B Sarwer; Ronette L Kolotkin; Walter Pories; Alison J Huang
Journal:  Surg Obes Relat Dis       Date:  2016-09-28       Impact factor: 4.734

Review 4.  A review of the psychosocial aspects of clinically severe obesity and bariatric surgery.

Authors:  David B Sarwer; Leslie J Heinberg
Journal:  Am Psychol       Date:  2020 Feb-Mar

5.  4-Year Changes in Sex Hormones, Sexual Functioning, and Psychosocial Status in Women Who Underwent Bariatric Surgery.

Authors:  David B Sarwer; Thomas A Wadden; Jacqueline C Spitzer; James E Mitchell; Kathy Lancaster; Anita Courcoulas; William Gourash; Raymond C Rosen; Nicholas J Christian
Journal:  Obes Surg       Date:  2018-04       Impact factor: 4.129

6.  Bariatric Surgery Candidates' Peer and Romantic Relationships and Associations with Health Behaviors.

Authors:  Keeley J Pratt; Elizabeth K Balk; Megan Ferriby; Lorraine Wallace; Sabrena Noria; Bradley Needleman
Journal:  Obes Surg       Date:  2016-11       Impact factor: 4.129

7.  Implanted Muscle-Derived Stem Cells Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes, but Their Repair Capacity Is Impaired by Their Prior Exposure to the Diabetic Milieu.

Authors:  Istvan Kovanecz; Dolores Vernet; Maryam Masouminia; Robert Gelfand; Leila Loni; James Aboagye; James Tsao; Jacob Rajfer; Nestor F Gonzalez-Cadavid
Journal:  J Sex Med       Date:  2016-05       Impact factor: 3.802

8.  Association Between Body Mass Index and Female Sexual Dysfunction: A Cross-sectional Study from the Data Registry on Experiences of Aging, Menopause, and Sexuality.

Authors:  Stephanie S Faubion; Flavia Fairbanks; Carol L Kuhle; Richa Sood; Juliana M Kling; Jennifer A Vencill; Kristin C Mara; Ekta Kapoor
Journal:  J Sex Med       Date:  2020-08-06       Impact factor: 3.802

Review 9.  Obesity and Sexual Functioning.

Authors:  David B Sarwer; Alexis J Hanson; Jessica Voeller; Kristine Steffen
Journal:  Curr Obes Rep       Date:  2018-12

10.  Influence of Gastric Bypass on Obese Women Sexual Function-a Prospective Study.

Authors:  Mariano de Almeida Menezes; Fernando Augusto Mardiros Herbella; Guilherme de Godoy Dos Santos; Antônio Carlos Valezi
Journal:  Obes Surg       Date:  2021-06-09       Impact factor: 4.129

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