Literature DB >> 24106508

Morphometrical dimensions of the sheep thoracolumbar vertebrae as seen on digitised CT images.

Mahmoud Mageed1, Dagmar Berner, Henriette Jülke, Christian Hohaus, Walter Brehm, Kerstin Gerlach.   

Abstract

The sheep spine is widely used as a model for preclinical research in human medicine to test new spinal implants and surgical procedures. Therefore, precise morphometric data are needed. The present study aimed to provide computed tomographic (CT) morphometry of sheep thoracolumbar spine. Five adult normal Merino sheep were included in this study. Sheep were anaesthetised and positioned in sternal recumbency. Subsequently, transverse and sagittal images were obtained using a multi-detector-row helical CT scanner. Measurements of the vertebral bodies, pedicles, intervertebral disc and transverse processes were performed with dedicated software. Vertebral bodies and the spinal canal were wider than they were deep, most obviously in the lumbar vertebrae. The intervertebral discs were as much as 57.4% thicker in the lumbar than in the thoracic spine. The pedicles were higher and longer than they were wide over the entire thoracolumbar spine. In conclusion, the generated data can serve as a CT reference for the ovine thoracolumbar spine and may be helpful in using sheep spine as a model for human spinal research.

Entities:  

Keywords:  Ovine; animal model; computed tomography; reference values; spine anatomy

Year:  2013        PMID: 24106508      PMCID: PMC3791347          DOI: 10.5625/lar.2013.29.3.138

Source DB:  PubMed          Journal:  Lab Anim Res        ISSN: 1738-6055


  41 in total

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Review 5.  Spinal biomechanics and functional anatomy.

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Journal:  Vet Clin North Am Equine Pract       Date:  1999-04       Impact factor: 1.792

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Journal:  Spine (Phila Pa 1976)       Date:  1995-01-15       Impact factor: 3.468

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Journal:  Clin Biomech (Bristol, Avon)       Date:  1994-05       Impact factor: 2.063

9.  Experiences with sheep as an animal model for shoulder surgery: strengths and shortcomings.

Authors:  A Simon Turner
Journal:  J Shoulder Elbow Surg       Date:  2007-05-15       Impact factor: 3.019

Review 10.  The potential of sheep for the study of osteopenia: current status and comparison with other animal models.

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Journal:  Bone       Date:  1995-04       Impact factor: 4.398

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  7 in total

1.  Morphometry of lumbar spinous process via three dimensional CT reconstruction in a Chinese population.

Authors:  Bo Ran; Qiang Li; Baoqing Yu; Xiangyang Chen; Kaijin Guo
Journal:  Int J Clin Exp Med       Date:  2015-01-15

2.  Percutaneous posterolateral approach for the simulation of a far-lateral disc herniation in an ovine model.

Authors:  Stefan Schwan; Christopher Ludtka; Ingo Wiesner; Andre Baerthel; Andrea Friedmann; Felix Göhre
Journal:  Eur Spine J       Date:  2017-10-27       Impact factor: 3.134

3.  Is sheep lumbar spine a suitable alternative model for human spinal researches? Morphometrical comparison study.

Authors:  Mahmoud Mageed; Dagmar Berner; Henriette Jülke; Christian Hohaus; Walter Brehm; Kerstin Gerlach
Journal:  Lab Anim Res       Date:  2013-12-20

4.  Intervertebral Disc Regeneration Injection of a Cell-Loaded Collagen Hydrogel in a Sheep Model.

Authors:  Andrea Friedmann; Andre Baertel; Christine Schmitt; Christopher Ludtka; Javorina Milosevic; Hans-Joerg Meisel; Felix Goehre; Stefan Schwan
Journal:  Int J Mol Sci       Date:  2021-04-19       Impact factor: 5.923

Review 5.  The Translational Benefits of Sheep as Large Animal Models of Human Neurological Disorders.

Authors:  Samantha J Murray; Nadia L Mitchell
Journal:  Front Vet Sci       Date:  2022-02-15

6.  Safe corridor for the implantation of thoracolumbar pedicle screws in growing pigs: A morphometric study.

Authors:  Thibaut Cachon; Paul Pillard; Thierry Odent; Claude Carozzo; Eric Viguier
Journal:  PLoS One       Date:  2017-10-23       Impact factor: 3.240

7.  A morphometric analysis of thoracolumbar vertebrae in goat by computed tomography.

Authors:  Josephine Roels; Roy Hassoun; M Massenzio; S Ronel; Y Lafon; Eric Viguier; Thibaut Cachon
Journal:  Vet Anim Sci       Date:  2022-01-17
  7 in total

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