Literature DB >> 2398904

The promoter and first, untranslated exon of the human glucocorticoid receptor gene are GC rich but lack consensus glucocorticoid receptor element sites.

J Zong1, J Ashraf, E B Thompson.   

Abstract

Glucocorticoid receptor mRNA is regulated by glucocorticoids. We found no consensus glucocorticoid response element, TATA box, or CAAT box but many GC boxes in approximately 3 kilobases of the 5'-flanking sequence of the human glucocorticoid receptor gene. We identified several transcription start sites, an untranslated exon 1, and the coding content of exon 2.

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Year:  1990        PMID： 2398904      PMCID： PMC361279          DOI： 10.1128/mcb.10.10.5580-5585.1990

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  39 in total

1.  Glucocorticoid effects on myeloma cells in culture: correlation of growth inhibition with induction of glucocorticoid receptor messenger RNA.

Authors:  M Gomi; K Moriwaki; S Katagiri; Y Kurata; E B Thompson
Journal:  Cancer Res       Date:  1990-03-15       Impact factor: 12.701

2.  Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A.

Authors:  S Green; P Walter; V Kumar; A Krust; J M Bornert; P Argos; P Chambon
Journal:  Nature       Date:  1986 Mar 13-19       Impact factor: 49.962

3.  Purification and biochemical characterization of the promoter-specific transcription factor, Sp1.

Authors:  M R Briggs; J T Kadonaga; S P Bell; R Tjian
Journal:  Science       Date:  1986-10-03       Impact factor: 47.728

4.  Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins.

Authors:  W S Dynan; R Tjian
Journal:  Nature       Date:  1985 Aug 29-Sep 4       Impact factor: 49.962

Review 5.  Glucocorticoid receptor regulation.

Authors:  F Svec
Journal:  Life Sci       Date:  1985-06-24       Impact factor: 5.037

6.  Modulation of glucocorticoid receptors by mitogenic stimuli, glucocorticoids and retinoids in normal human cultured T cells.

Authors:  A Lacroix; G D Bonnard; M E Lippman
Journal:  J Steroid Biochem       Date:  1984-07       Impact factor: 4.292

7.  Functional domains of the human glucocorticoid receptor.

Authors:  V Giguère; S M Hollenberg; M G Rosenfeld; R M Evans
Journal:  Cell       Date:  1986-08-29       Impact factor: 41.582

8.  Stress down-regulates corticosterone receptors in a site-specific manner in the brain.

Authors:  R M Sapolsky; L C Krey; B S McEwen
Journal:  Endocrinology       Date:  1984-01       Impact factor: 4.736

9.  Triamcinolone acetonide regulates glucocorticoid-receptor levels by decreasing the half-life of the activated nuclear-receptor form.

Authors:  W R McIntyre; H H Samuels
Journal:  J Biol Chem       Date:  1985-01-10       Impact factor: 5.157

10.  Primary structure and expression of a functional human glucocorticoid receptor cDNA.

Authors:  S M Hollenberg; C Weinberger; E S Ong; G Cerelli; A Oro; R Lebo; E B Thompson; M G Rosenfeld; R M Evans
Journal:  Nature       Date:  1985-12-19       Impact factor: 49.962
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  21 in total

1.  At least three promoters direct expression of the mouse glucocorticoid receptor gene.

Authors:  U Strähle; A Schmidt; G Kelsey; A F Stewart; T J Cole; W Schmid; G Schütz
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-01       Impact factor: 11.205

2.  Characterization of the DNA target site for the yeast ARGR regulatory complex, a sequence able to mediate repression or induction by arginine.

Authors:  M De Rijcke; S Seneca; B Punyammalee; N Glansdorff; M Crabeel
Journal:  Mol Cell Biol       Date:  1992-01       Impact factor: 4.272

3.  The glucocorticoid receptor and c-jun promoters contain AP-1 sites that bind different AP-1 transcription factors.

Authors:  M B Breslin; W V Vedeckis
Journal:  Endocrine       Date:  1996-08       Impact factor: 3.633

4.  Attenuation of glucocorticoid receptor levels by the H-ras oncogene.

Authors:  V R Martins; M M Brentani; P R Housley
Journal:  Endocrine       Date:  1995-04       Impact factor: 3.633

5.  A new, lineage specific, autoup-regulation mechanism for human glucocorticoid receptor gene expression in 697 pre-B-acute lymphoblastic leukemia cells.

Authors:  Chuan-dong Geng; Wayne V Vedeckis
Journal:  Mol Endocrinol       Date:  2010-11-17

6.  DNA Methylation Profiles of Protease Nexin 1 (SERPINE2) Gene in Human Cell Lines.

Authors:  Shan Gao; Peter A Andreasen
Journal:  Chin J Cancer Res       Date:  2011-06       Impact factor: 5.087

7.  Sexual dimorphism of stress response and immune/ inflammatory reaction: the corticotropin releasing hormone perspective.

Authors:  N V Vamvakopoulos
Journal:  Mediators Inflamm       Date:  1995       Impact factor: 4.711

8.  Regulation of the glucocorticoid receptor gene by the AP-1 transcription factor.

Authors:  P Wei; W V Vedeckis
Journal:  Endocrine       Date:  1997-12       Impact factor: 3.633

9.  A conserved molecular mechanism is responsible for the auto-up-regulation of glucocorticoid receptor gene promoters.

Authors:  Chuan-dong Geng; Jason R Schwartz; Wayne V Vedeckis
Journal:  Mol Endocrinol       Date:  2008-10-22

10.  Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer.

Authors:  Dmitri V Rozanov; Alexei Y Savinov; Roy Williams; Kang Liu; Vladislav S Golubkov; Stan Krajewski; Alex Y Strongin
Journal:  Cancer Res       Date:  2008-06-01       Impact factor: 12.701
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