Literature DB >> 2867473

Primary structure and expression of a functional human glucocorticoid receptor cDNA.

S M Hollenberg, C Weinberger, E S Ong, G Cerelli, A Oro, R Lebo, E B Thompson, M G Rosenfeld, R M Evans.   

Abstract

Identification of complementary DNAs encoding the human glucocorticoid receptor predicts two protein forms, of 777 (alpha) and 742 (beta) amino acids, which differ at their carboxy termini. The proteins contain a cysteine/lysine/arginine-rich region which may define the DNA-binding domain. Pure radiolabelled glucocorticoid receptor, synthesized in vitro, is immunoreactive and possesses intrinsic steroid-binding activity characteristic of the native glucocorticoid receptor.

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Year:  1985        PMID： 2867473      PMCID： PMC6165583          DOI： 10.1038/318635a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  62 in total

Review 1.  Current models of steroid hormone action: a critique.

Authors:  J Gorski; F Gannon
Journal:  Annu Rev Physiol       Date:  1976       Impact factor: 19.318

Review 2.  Steroid receptors: elements for modulation of eukaryotic transcription.

Authors:  K R Yamamoto; B M Alberts
Journal:  Annu Rev Biochem       Date:  1976       Impact factor: 23.643

3.  Immunochemical analysis of the glucocorticoid receptor: identification of a third domain separate from the steroid-binding and DNA-binding domains.

Authors:  J Carlstedt-Duke; S Okret; O Wrange; J A Gustafsson
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

Review 4.  Variety in the level of gene control in eukaryotic cells.

Authors:  J E Darnell
Journal:  Nature       Date:  1982-06-03       Impact factor: 49.962

5.  Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells.

Authors:  R Miesfeld; S Okret; A C Wikström; O Wrange; J A Gustafsson; K R Yamamoto
Journal:  Nature       Date:  1984 Dec 20-1985 Jan 2       Impact factor: 49.962

6.  Characterization of a monoclonal antibody to the rat liver glucocorticoid receptor.

Authors:  B Gametchu; R W Harrison
Journal:  Endocrinology       Date:  1984-01       Impact factor: 4.736

7.  Characterization of the purified activated glucocorticoid receptor from rat liver cytosol.

Authors:  O Wrange; S Okret; M Radojćić; J Carlstedt-Duke; J A Gustafsson
Journal:  J Biol Chem       Date:  1984-04-10       Impact factor: 5.157

8.  Metallothionein mRNA induction in HeLa cells in response to zinc or dexamethasone is a primary induction response.

Authors:  M Karin; R D Andersen; E Slater; K Smith; H R Herschman
Journal:  Nature       Date:  1980-07-17       Impact factor: 49.962

9.  The glucocorticoid receptor binds to defined nucleotide sequences near the promoter of mouse mammary tumour virus.

Authors:  C Scheidereit; S Geisse; H M Westphal; M Beato
Journal:  Nature       Date:  1983 Aug 25-31       Impact factor: 49.962

10.  Monoclonal antibodies to the rat liver glucocorticoid receptor.

Authors:  H M Westphal; G Moldenhauer; M Beato
Journal:  EMBO J       Date:  1982       Impact factor: 11.598
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  318 in total

Review 1.  Molecular mechanisms of glucocorticoid action: what is important?

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Journal:  Thorax       Date:  2000-07       Impact factor: 9.139

Review 2.  Clinical pharmacology of inflammatory bowel disease therapies.

Authors:  W J Sandborn; W A Faubion
Journal:  Curr Gastroenterol Rep       Date:  2000-12

Review 3.  Glucocorticoid-resistant asthma.

Authors:  Tuck-Kay Loke; Ana R Sousa; Christopher J Corrigan; Tak H Lee
Journal:  Curr Allergy Asthma Rep       Date:  2002-03       Impact factor: 4.806

4.  Mutations in the hormone regulatory element of mouse mammary tumor virus differentially affect the response to progestins, androgens, and glucocorticoids.

Authors:  P L Gowland; E Buetti
Journal:  Mol Cell Biol       Date:  1989-09       Impact factor: 4.272

Review 5.  Role of central mineralocorticoid receptors in cardiovascular disease.

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Journal:  Curr Hypertens Rep       Date:  2001-06       Impact factor: 5.369

6.  Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.

Authors:  Florian P Limbourg; Zhihong Huang; Jean-Christophe Plumier; Tommaso Simoncini; Masayuki Fujioka; Jan Tuckermann; Günther Schütz; Michael A Moskowitz; James K Liao
Journal:  J Clin Invest       Date:  2002-12       Impact factor: 14.808

7.  Circadian rhythms of glucocorticoid hormone actions in target tissues: potential clinical implications.

Authors:  Tomoshige Kino
Journal:  Sci Signal       Date:  2012-10-02       Impact factor: 8.192

8.  Structural characterization of a minimal functional transactivation domain from the human glucocorticoid receptor.

Authors:  K Dahlman-Wright; H Baumann; I J McEwan; T Almlöf; A P Wright; J A Gustafsson; T Härd
Journal:  Proc Natl Acad Sci U S A       Date:  1995-02-28       Impact factor: 11.205

Review 9.  The Roles of Xenobiotic Receptors: Beyond Chemical Disposition.

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Journal:  Drug Metab Dispos       Date:  2018-05-14       Impact factor: 3.922

10.  Phosphorylation of immunopurified rat liver glucocorticoid receptor by the catalytic subunit of cAMP-dependent protein kinase.

Authors:  T Haske; M Nakao; V K Moudgil
Journal:  Mol Cell Biochem       Date:  1994-03-30       Impact factor: 3.396
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