| Literature DB >> 3754034 |
S Green, P Walter, V Kumar, A Krust, J M Bornert, P Argos, P Chambon.
Abstract
We have cloned and sequenced the complete complementary DNA of the oestrogen receptor (ER) present in the breast cancer cell line MCF-7. The expression of the ER cDNA in HeLa cells produces a protein that has the same relative molecular mass and binds oestradiol with the same affinity as the MCF-7 ER. There is extensive homology between the ER and the erb-A protein of the oncogenic avian erythroblastosis virus.Entities:
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Year: 1986 PMID： 3754034 DOI： 10.1038/320134a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962