Christian Seitz1, Harun Fajkovic. 1. Department of Urology, Vienna General Hospital, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria, drseitz@gmx.at.
Abstract
PURPOSE: The incidence of urolithiasis is worldwide increasing and contributes to a rising economic and health care burden. The objective of this review is to identify gender differences in urolithiasis epidemiology in Europe and the USA as well as gender-specific risk factors for urolithiasis. EVIDENCE ACQUISITION: A systematic review of the present literature was performed including English journals without a time limit. The MeSH terms used were as follows: ("Sex Characteristics"[Mesh]) AND "Urolithiasis"[Mesh] or ("Epidemiology"[Mesh]) AND "Urolithiasis"[Mesh]. Additionally, reference search of retrieved papers identified additional references. The MEDLINE database was searched. EVIDENCE SYNTHESIS: The prevalence of urolithiasis is rising worldwide including both genders in different age groups. Especially women face an increase in prevalence in the USA. Overweight seems to be an important cause for this development. Additionally insulin resistance and hypertonia, conditions present in the metabolic syndrome complex, contribute to this phenomenon. CONCLUSION: Stone prevalence across all age groups and both genders is increasing. Lifestyle changes along with increasing prevalence of obesity are key factors for this development. Female gender did significantly differ in the risk ratio of stone development in different variables including body mass index, hyperinsulinemia, and hypertension. It is important to inform the public on measures how to change lifestyle and dietary measures for preventing or lowering events of stone disease.
PURPOSE: The incidence of urolithiasis is worldwide increasing and contributes to a rising economic and health care burden. The objective of this review is to identify gender differences in urolithiasis epidemiology in Europe and the USA as well as gender-specific risk factors for urolithiasis. EVIDENCE ACQUISITION: A systematic review of the present literature was performed including English journals without a time limit. The MeSH terms used were as follows: ("Sex Characteristics"[Mesh]) AND "Urolithiasis"[Mesh] or ("Epidemiology"[Mesh]) AND "Urolithiasis"[Mesh]. Additionally, reference search of retrieved papers identified additional references. The MEDLINE database was searched. EVIDENCE SYNTHESIS: The prevalence of urolithiasis is rising worldwide including both genders in different age groups. Especially women face an increase in prevalence in the USA. Overweight seems to be an important cause for this development. Additionally insulin resistance and hypertonia, conditions present in the metabolic syndrome complex, contribute to this phenomenon. CONCLUSION: Stone prevalence across all age groups and both genders is increasing. Lifestyle changes along with increasing prevalence of obesity are key factors for this development. Female gender did significantly differ in the risk ratio of stone development in different variables including body mass index, hyperinsulinemia, and hypertension. It is important to inform the public on measures how to change lifestyle and dietary measures for preventing or lowering events of stone disease.
Authors: Armando Luis Negri; Francisco Rodolfo Spivacow; Elisa Elena Del Valle; Mariano Forrester; Gabriela Rosende; Irene Pinduli Journal: Urol Res Date: 2008-11-05
Authors: J Mueller; N Riechert-Mühe; A J Schrader; A Leitenberger; J Steinestel; M A Kuczyk; S Steffens; R Hofmann; J Sotelino Journal: Urologe A Date: 2014-11 Impact factor: 0.639
Authors: M Özsoy; Ö Acar; K Sarica; Z Saratlija-Novakovic; H Fajkovic; D Librenjak; T Esen; N Scheffbuch; C Seitz Journal: World J Urol Date: 2014-11-12 Impact factor: 4.226
Authors: Ranan Dasgupta; Sarah Cameron; Lorna Aucott; Graeme MacLennan; Mary M Kilonzo; Thomas Bl Lam; Ruth Thomas; John Norrie; Alison McDonald; Ken Anson; James N'Dow; Neil Burgess; Charles T Clark; Francis X Keeley; Sara J MacLennan; Kath Starr; Samuel McClinton Journal: Health Technol Assess Date: 2022-03 Impact factor: 4.014
Authors: Tim Nestler; Kai Nestler; Andreas Neisius; Hendrik Isbarn; Christopher Netsch; Stephan Waldeck; Hans U Schmelz; Christian Ruf Journal: World J Urol Date: 2018-08-03 Impact factor: 4.226